M
Marc A. Pfeffer
Researcher at Brigham and Women's Hospital
Publications - 815
Citations - 143710
Marc A. Pfeffer is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 166, co-authored 765 publications receiving 133043 citations. Previous affiliations of Marc A. Pfeffer include Partners HealthCare & University of Miami.
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Journal ArticleDOI
International Geographic Variation in Event Rates in Trials of Heart Failure With Preserved and Reduced Ejection Fraction
Søren Lund Kristensen,Lars Køber,Pardeep S. Jhund,Scott D. Solomon,John Kjekshus,Robert S. McKelvie,Michael R. Zile,Christopher B. Granger,John Wikstrand,Michel Komajda,Peter E. Carson,Marc A. Pfeffer,Karl Swedberg,Hans Wedel,Salim Yusuf,John J.V. McMurray +15 more
TL;DR: The differences in event rates observed suggest there is international geographic variation in 1 or more of the definition and diagnosis of HF-PEF, the risk profile of patients enrolled, and the threshold for hospitalization, which has implications for the conduct of future global trials.
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Influence of Albuminuria on Cardiovascular Risk in Patients With Stable Coronary Artery Disease
Scott D. Solomon,Julie Lin,Caren G. Solomon,Kathleen A. Jablonski,Madeline Murguia Rice,Michael W. Steffes,Michael J. Domanski,Judith Hsia,Bernard J. Gersh,J. Malcolm O. Arnold,Jean L. Rouleau,Eugene Braunwald,Marc A. Pfeffer +12 more
TL;DR: It is shown that albuminuria, even in low levels within the normal range, is an independent predictor of cardiovascular and all-cause mortality.
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Which Inhibitor of the Renin–Angiotensin System Should Be Used in Chronic Heart Failure and Acute Myocardial Infarction?
TL;DR: The evaluation of the effects of ARBs in CHF and AMI has been challenging because of the incontrovertible role of ACE inhibitors, raising questions about trial design, dose selection, statistics, and even ethics.
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Prevalence and prognostic importance of precipitating factors leading to heart failure hospitalization: recurrent hospitalizations and mortality.
Elke Platz,Pardeep S. Jhund,Brian Claggett,Marc A. Pfeffer,Karl Swedberg,Karl Swedberg,Christopher B. Granger,Salim Yusuf,Scott D. Solomon,John J.V. McMurray +9 more
TL;DR: Hospitalizations for heart failure are common and are associated with significant morbidity, mortality and cost, but precipitating factors leading to HF hospitalization and their importance with respect to subsequent outcomes are not well understood.
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Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: The TOPCAT Trial
Maja Cikes,Brian Claggett,Amil M. Shah,Akshay S. Desai,Eldrin F. Lewis,Sanjiv J. Shah,Inder S. Anand,Eileen O'Meara,Jean L. Rouleau,Nancy K. Sweitzer,James C. Fang,Sanjeev Saksena,Bertram Pitt,Marc A. Pfeffer,Scott D. Solomon +14 more
TL;DR: AF at enrollment was associated with increased cardiovascular risk in HFpEF patients in the TOPCAT study and spironolactone influenced post-randomization AF was not influenced.