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Marc A. Pfeffer

Researcher at Brigham and Women's Hospital

Publications -  815
Citations -  143710

Marc A. Pfeffer is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 166, co-authored 765 publications receiving 133043 citations. Previous affiliations of Marc A. Pfeffer include Partners HealthCare & University of Miami.

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Left ventricular diastolic pressure-volume relations in rats with healed myocardial infarction. Effects on systolic function.

TL;DR: An impairment of cardiac performance correlated with the infarct size-related increase in diastolic volume, which served to offset the reduction in flow generating capacity caused by systolic dysfunction, while contributing directly to the impairment of pressure generating capacity.
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2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials.

TL;DR: This publication describes uniform definitions for cardiovascular and stroke outcomes developed by the Standardized Data Collection for Cardiovascular Trials Initiative and the US Food and Drug Administration.
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Effect of Pravastatin on Cardiovascular Events in People With Chronic Kidney Disease

TL;DR: Pravastatin reduces cardiovascular event rates in people with or at risk for coronary disease and concomitant moderate CKD, many of whom have serum creatinine levels within the normal range, and the absolute benefit that resulted from use of pravastsatin was greater than in those with normal renal function.
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Cardiovascular Outcomes in the Irbesartan Diabetic Nephropathy Trial of Patients with Type 2 Diabetes and Overt Nephropathy

TL;DR: The analysis of the cardiovascular end points that were monitored as secondary end points in the Irbesartan Diabetic Nephropathy Trial (IDNT) was reported to assess whether an angiotensin II receptor blocker or a calcium-channel blocker alters the risk for cardiovascular events beyond those observed by blood pressure reduction alone without such agents.