Marc A. Pfeffer

TL;DR: It is hypothesized that this remodeling of the infarcted left ventricle was a response to an increase in both systolic and diastolic wall stresses and that captopril, by reducing wall stress, would attenuate the process, and that the potential exists for the attenuation of progressive ventricular enlargement and improved survival of patients recovering from a myocardial infarction.

TL;DR: Treatment with a high-dose folic acid, B6, and B12 multivitamin in kidney transplant recipients did not reduce a composite cardiovascular disease outcome, all-cause mortality, or dialysis-dependent kidney failure despite significant reduction in homocysteine level.

TL;DR: Stage 2 or early stage 3 CKD and diabetes both are associated with higher cardiovascular risk, and pravastatin reduces cardiovascular event rates in people with neither, one, or both characteristics.

TL;DR: The present results support the early use of ACEi in acute MI, irrespective of whether or not ASA is being given, and both ASA and ACEi are beneficial in acuteMI.

TL;DR: Angiotensin receptor blockers appear to be as effective as ACE inhibitors in reducing atherosclerotic events, even when used in addition to other secondary preventive treatments, and support the hypothesis that adding an ARB to an ACE inhibitor may have a small additional anti-infarction effect.