M
Marc A. Pfeffer
Researcher at Brigham and Women's Hospital
Publications - 815
Citations - 143710
Marc A. Pfeffer is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 166, co-authored 765 publications receiving 133043 citations. Previous affiliations of Marc A. Pfeffer include Partners HealthCare & University of Miami.
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Patent
Use of angiotensin antagonist (at1) for reducing post myocardial infarct mobidity and mortality
TL;DR: In this paper, a method for treating a human survivor of a heart attack and providing further improvement in survival following the heart attack by the early initiation and long-term administration of a renin-angiotensin system inhibitor, preferably an angio-ensin converting enzyme inhibitor.
Journal ArticleDOI
Right Ventricular Function and Coupling to Pulmonary Circulation in Heart Failure with Preserved Ejection Fraction: The PARAGON-HF Trial.
Riccardo M. Inciardi,Martin Hongieh Abanda,Amil M. Shah,Maja Cikes,Brian Claggett,Hicham Skali,Muthiah Vaduganathan,Narayana Prasad,Sheldon E. Litwin,Béla Merkely,Annamaria Kosztin,Klaudia Vivien Nagy,Wilfred Mullens,Michael R. Zile,Carolyn S.P. Lam,Marc A. Pfeffer,John J.V. McMurray,Scott D. Solomon +17 more
TL;DR: The PARAGON-HF trial as mentioned in this paper was used to assess the clinical implications of right ventricular (RV) function and the association with N-terminal pro-B-type natriuretic-peptide (NT-proBNP) and the risk for adverse events among left ventricular ejection fraction (HFpEF) patients.
Journal ArticleDOI
OR-37: Omapatrilat reduces pulse pressure and proximal aortic stiffness in patients with systolic hypertension. Results of the conduit hemodynamics of omapatrilat international research (CHOIR) study
Gary F. Mitchell,Yves Lacourcière,Jean-Pascal Ouellet,Joseph L. Izzo,Joel M. Neutel,Chunlin Qian,Linda J. Kerwin,Alan J. Block,Marc A. Pfeffer +8 more
TL;DR: Greater reductions in pulse pressure and Zc in hypertensive subjects treated with omapatrilat compared with enalapril suggest that aortic stiffness is maintained by specific, partially reversible mechanisms and underscore a potential role for pharmacological modulation of natriuretic peptides in the treatment of hypertension.
Journal ArticleDOI
Candesartán reduce moderadamente los ingresos hospitalarios en pacientes con insuficiencia cardíaca crónica y función sistólica preservada
Salim Yusuf,Marc A. Pfeffer,Karl Swedberg,C.B. Granger,P. Held,Jjv McMurray,José M. Lobos Bejarano +6 more
TL;DR: Los pacientes fueron aleatorizados para recibir candesartan y el objetivo primario principal fue the mortalidad of causa cardiovascular u hospitalizacion por IC.