M
Marc A. Pfeffer
Researcher at Brigham and Women's Hospital
Publications - 815
Citations - 143710
Marc A. Pfeffer is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 166, co-authored 765 publications receiving 133043 citations. Previous affiliations of Marc A. Pfeffer include Partners HealthCare & University of Miami.
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Journal ArticleDOI
Opposing Effects of β Blockers and Angiotensin-Converting Enzyme Inhibitors on Development of New-Onset Diabetes Mellitus in Patients With Stable Coronary Artery Disease
Orly Vardeny,Hajime Uno,Eugene Braunwald,Jean L. Rouleau,Bernard J. Gersh,Aldo P. Maggioni,Michael J. Domanski,Marc A. Pfeffer,Scott D. Solomon +8 more
TL;DR: It is suggested that ACE inhibition may attenuate the risk for glucose abnormalities observed in patients taking β blockers, and this risk was decreased in patients treated concurrently with an ACE inhibitor.
Journal ArticleDOI
Composite outcomes: weighting component events according to severity assisted interpretation but reduced statistical power.
TL;DR: The composite score provides a more informative measure of disease burden and may avoid overestimating the evidence supporting a treatment effect when that evidence is largely from less severe early events.
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Circumstances and Outcomes of Sudden Unexpected Death in Patients With High-Risk Myocardial Infarction Implications for Prevention
Siqin Ye,Matthew Grunnert,Jens Jakob Thune,Kent Stephenson,Hajime Uno,Peter V. Finn,John J.V. McMurray,Eric J. Velazquez,Robert M. Califf,Marc A. Pfeffer,Scott D. Solomon +10 more
TL;DR: A high proportion of SD events after high-risk myocardial infarction occurred at home, but in-hospital events were more common early on.
Journal ArticleDOI
Prior Pacemaker Implantation and Clinical Outcomes in Patients With Heart Failure and Preserved Ejection Fraction.
Li Shen,Pardeep S. Jhund,Kieran F. Docherty,Mark C. Petrie,Inder S. Anand,Peter E. Carson,Akshay S. Desai,Christopher B. Granger,Michel Komajda,Robert S. McKelvie,Marc A. Pfeffer,Scott D. Solomon,Karl Swedberg,Michael R. Zile,John J.V. McMurray,John J.V. McMurray +15 more
TL;DR: Findings raise the possibility that right ventricular pacing-induced left ventricular dyssynchrony may be detrimental in patients with heart failure with preserved ejection fraction (HFpEF).
Journal ArticleDOI
Clinical characteristics and outcomes of patients with angina and heart failure in the CHARM (Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity) Programme.
Athar A. Badar,Athar A. Badar,Ana Cristina Perez-Moreno,Nathaniel M. Hawkins,Alan P.T. Brunton,Pardeep S. Jhund,Chih M. Wong,Scott D. Solomon,Christopher B. Granger,Salim Yusuf,Marc A. Pfeffer,Karl Swedberg,Karl Swedberg,Roy S. Gardner,Roy S. Gardner,Mark C. Petrie,Mark C. Petrie,John J.V. McMurray +17 more
TL;DR: To investigate the relationship between angina pectoris and fatal and non‐fatal clinical outcomes in heart failure with reduced and preserved ejection fraction (HF‐REF and HF‐PEF, respectively).