M
Maria Carolina Amezcua Vesely
Researcher at Yale University
Publications - 21
Citations - 1549
Maria Carolina Amezcua Vesely is an academic researcher from Yale University. The author has contributed to research in topics: Immune system & Cytokine. The author has an hindex of 13, co-authored 19 publications receiving 1037 citations. Previous affiliations of Maria Carolina Amezcua Vesely include National Scientific and Technical Research Council & National University of Cordoba.
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Journal ArticleDOI
Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation
Nicola Gagliani,Maria Carolina Amezcua Vesely,Andrea Iseppon,Leonie Brockmann,Hao Xu,Noah W. Palm,Marcel R. de Zoete,Paula Licona-Limón,Ricardo Paiva,Travers Ching,Casey T. Weaver,Xiaoyuan Zi,Xinghua Pan,Rong Fan,Lana X. Garmire,Matthew J. Cotton,Yotam Drier,Bradley E. Bernstein,Jens Geginat,Brigitta Stockinger,Enric Esplugues,Samuel Huber,Richard A. Flavell +22 more
TL;DR: Two new fate-mapping mouse models are used to show that CD4+ T cells that formerly expressed IL-17A go on to acquire an anti-inflammatory phenotype and suggest that Th17 cell instability and plasticity is a therapeutic opportunity for inflammatory diseases.
Journal ArticleDOI
m 6 A mRNA methylation sustains Treg suppressive functions
Journal ArticleDOI
IL-17RA signaling reduces inflammation and mortality during Trypanosoma cruzi infection by recruiting suppressive IL-10-producing neutrophils.
Jimena Tosello Boari,Maria Carolina Amezcua Vesely,Daniela A. Bermejo,María Cecilia Ramello,Carolina L. Montes,Hugo Cejas,Adriana Gruppi,Eva Virginia Acosta Rodriguez +7 more
TL;DR: The role of IL-17RA is underscored in the modulation of IFN-γ-mediated inflammatory responses during infections and a previously unrecognized regulatory mechanism that involves the IL- 17RA-mediated recruitment of suppressive IL-10-producing neutrophils is uncovered.
Journal ArticleDOI
Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection.
Maria Carolina Amezcua Vesely,Paris Pallis,Piotr Bielecki,Jun Siong Low,Jun Zhao,Christian C. D. Harman,Lina Kroehling,Ruaidhri Jackson,Will Bailis,Paula Licona-Limón,Hao Xu,Norifumi Iijima,Padmini S. Pillai,Daniel H. Kaplan,Casey T. Weaver,Yuval Kluger,Monika S. Kowalczyk,Akiko Iwasaki,João Pereira,Enric Esplugues,Nicola Gagliani,Nicola Gagliani,Nicola Gagliani,Richard A. Flavell +23 more
TL;DR: It is found that a significant fraction of lung CD4 TRM cells derive from IL-17A-producing effector (TH17) cells following immunization with heat-killed Klebsiella pneumonia (Kp).
Journal ArticleDOI
Skin-resident innate lymphoid cells converge on a pathogenic effector state.
Piotr Bielecki,Samantha J. Riesenfeld,Samantha J. Riesenfeld,Jan-Christian Hütter,Elena Torlai Triglia,Monika S. Kowalczyk,Roberto R. Ricardo-Gonzalez,Mi Lian,Mi Lian,Maria Carolina Amezcua Vesely,Maria Carolina Amezcua Vesely,Lina Kroehling,Hao Xu,Michal Slyper,Christoph Muus,Christoph Muus,Leif S. Ludwig,Elena Christian,Liming Tao,Amanda J. Kedaigle,Holly R. Steach,Autumn G. York,Mathias H. Skadow,Parastou Yaghoubi,Danielle Dionne,Abigail Jarret,Heather M. McGee,Heather M. McGee,Caroline B. M. Porter,Paula Licona-Limón,Paula Licona-Limón,Will Bailis,Will Bailis,Will Bailis,Ruaidhri Jackson,Nicola Gagliani,Georg Gasteiger,Richard M. Locksley,Richard M. Locksley,Aviv Regev,Richard A. Flavell,Richard A. Flavell +41 more
TL;DR: In this paper, the authors show that the induction of psoriasis in mice by IL-23 or imiquimod reconfigures a spectrum of skin ILCs, which converge on a pathogenic ILC3-like state.