M
Meena Kumari
Researcher at University of Essex
Publications - 434
Citations - 57017
Meena Kumari is an academic researcher from University of Essex. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 97, co-authored 407 publications receiving 49488 citations. Previous affiliations of Meena Kumari include Kansas State University & University of Copenhagen.
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Journal ArticleDOI
PLA2G7 Genotype, Lipoprotein-Associated Phospholipase A2 Activity, and Coronary Heart Disease Risk in 10 494 Cases and 15 624 Controls of European Ancestry
Juan P. Casas,Ewa Ninio,Andrie G. Panayiotou,Jutta Palmen,Jackie A. Cooper,Sally L. Ricketts,Reecha Sofat,Andrew N. Nicolaides,James P. Corsetti,F. Gerry R. Fowkes,Ioanna Tzoulaki,Meena Kumari,Eric J. Brunner,Mika Kivimäki,Michael Marmot,Michael Hoffmann,Karl Winkler,Winfred März,Shu Ye,Heide A. Stirnadel,S. Matthijs Boekholdt,Kay-Tee Khaw,Steve E. Humphries,Manjinder S. Sandhu,Aroon D. Hingorani,Philippa J. Talmud +25 more
TL;DR: Larger association studies, identification of single-nucleotide polymorphisms with larger effects, or randomized trials of specific Lp-PLA2 inhibitors are needed to confirm or refute a contributory role for Lp -PLA2 in CHD.
Journal ArticleDOI
Genetics of cortisol secretion and depressive symptoms: A candidate gene and genome wide association approach
Fleur P. Velders,Maris Kuningas,Meena Kumari,Marieke J. H. J. Dekker,André G. Uitterlinden,Clemens Kirschbaum,Karin Hek,Albert Hofman,Frank C. Verhulst,Mika Kivimäki,Cornelia M. van Duijn,Brian R. Walker,Henning Tiemeier +12 more
TL;DR: Variation in the FKBP5 gene is associated with both cortisol(AUC) and the likelihood of depressive symptoms and a genome wide association study of cortisol (GWAS) findings suggest this.
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Anne E. Justice,Thomas W. Winkler,Mary F. Feitosa,Misa Graff,Virginia Fisher,Kristin L. Young,Llilda Barata,Xuan Deng,Jacek Czajkowski,David Hadley,Julius S. Ngwa,Tarunveer S. Ahluwalia,Audrey Y. Chu,Nancy L. Heard-Costa,Elise Lim,Jeremiah Perez,John D. Eicher,Zoltán Kutalik,Luting Xue,Anubha Mahajan,Frida Renström,Joseph M. Wu,Qibin Qi,Shafqat Ahmad,Tamuno Alfred,Najaf Amin,Lawrence F. Bielak,Amélie Bonnefond,Jennifer Bragg,Gemma Cadby,Martina Chittani,Scott Coggeshall,Tanguy Corre,Nese Direk,Joel Eriksson,Krista Fischer,Mathias Gorski,Marie Neergaard Harder,Momoko Horikoshi,Tao Huang,Jennifer E. Huffman,Anne U. Jackson,Johanne Marie Justesen,Stavroula Kanoni,Leena Kinnunen,Marcus E. Kleber,Pirjo Komulainen,Meena Kumari,Unhee Lim,Jian'an Luan,Leo-Pekka Lyytikäinen,Massimo Mangino,Ani Manichaikul,Jonathan Marten,Rita P. S. Middelberg,Martina Mueller-Nurasyid,Pau Navarro,Louis Pérusse,Natalia Pervjakova,Cinzia Sarti,Albert V. Smith,Jennifer A. Smith,Alena Stančáková,Rona J. Strawbridge,Heather M. Stringham,Yun Ju Sung,Toshiko Tanaka,Alexander Teumer,Stella Trompet,Sander W. van der Laan,Peter J. van der Most,Jana V. van Vliet-Ostaptchouk,Sailaja Vedantam,Niek Verweij,Jacqueline M. Vink,Veronique Vitart,Ying Wu,Loic Yengo,Weihua Zhang,Jing Hua Zhao,Martina E. Zimmermann,Niha Zubair,Gonçalo R. Abecasis,Linda S. Adair,Saima Afaq,Uzma Afzal,Stephan J. L. Bakker,Traci M. Bartz,John Beilby,Richard N. Bergman,Sven Bergmann,Reiner Biffar,John Blangero,Eric Boerwinkle,Lori L. Bonnycastle,Erwin P. Bottinger,Daniele Braga,Brendan M. Buckley,Steve Buyske,Harry Campbell,John C. Chambers,Francis S. Collins,Joanne E. Curran,Gert J. de Borst,Anton J. M. de Craen,Eco J. C. de Geus,George Dedoussis,Graciela E. Delgado,Hester M. den Ruijter,Gudny Eiriksdottir,Anna Eriksson,Tõnu Esko,Jessica D. Faul,Ian Ford,Terrence Forrester,Karl Gertow,Bruna Gigante,Nicola Glorioso,Jian Gong,Harald Grallert,Tanja B. Grammer,Niels Grarup,Saskia Haitjema,Göran Hallmans,Anders Hamsten,Torben Hansen,Tamara B. Harris,Catharina A. Hartman,Maija Hassinen,Nicholas D. Hastie,Andrew Heath,Dena G. Hernandez,Lucia A. Hindorff,Lynne J. Hocking,Mette Hollensted,Oddgeir L. Holmen,Georg Homuth,Jouke-Jan Hottenga,Jie Huang,Joseph Hung,Nina Hutri-Kähönen,Erik Ingelsson,Alan James,John-Olov Jansson,Marjo-Riitta Järvelin,Min A. Jhun,Marit E. Jørgensen,Markus Juonala,Mika Kähönen,Magnus Karlsson,Heikki A. Koistinen,Ivana Kolcic,Genovefa Kolovou,Charles Kooperberg,Bernhard K. Krämer,Johanna Kuusisto,Kirsti Kvaløy,Timo A. Lakka,Claudia Langenberg,Lenore J. Launer,Karin Leander,Nanette R. Lee,Lars Lind,Cecilia M. Lindgren,Allan Linneberg,Stéphane Lobbens,Marie Loh,Mattias Lorentzon,Robert Luben,Gitta H. Lubke,Anja Ludolph-Donislawski,Sara Lupoli,Pamela A. F. Madden,Reija Männikkö,Pedro Marques-Vidal,Nicholas G. Martin,Colin A. McKenzie,Barbara McKnight,Dan Mellström,Cristina Menni,Grant W. Montgomery,Arthur W. Musk,Narisu Narisu,Matthias Nauck,Ilja M. Nolte,Albertine J. Oldehinkel,Matthias Olden,Ken K. Ong,Sandosh Padmanabhan,Patricia A. Peyser,Charlotta Pisinger,David J. Porteous,Olli T. Raitakari,Tuomo Rankinen,Dabeeru C. Rao,Laura J. Rasmussen-Torvik,Rajesh Rawal,Treva Rice,Paul M. Ridker,Lynda M. Rose,Stephanie A. Bien,Igor Rudan,Serena Sanna,Mark A. Sarzynski,Naveed Sattar,Kai Savonen,David Schlessinger,Salome Scholtens,Claudia Schurmann,Robert A. Scott,Bengt Sennblad,Marten A. Siemelink,Günther Silbernagel,P. Eline Slagboom,Harold Snieder,Jan A. Staessen,David J. Stott,Morris A. Swertz,Amy J. Swift,Kent D. Taylor,Bamidele O. Tayo,Barbara Thorand,Dorothée Thuillier,Jaakko Tuomilehto,André G. Uitterlinden,Liesbeth Vandenput,Marie-Claude Vohl,Henry Völzke,Judith M. Vonk,Gérard Waeber,Melanie Waldenberger,Rudi G. J. Westendorp,Sarah H. Wild,Gonneke Willemsen,Bruce H. R. Wolffenbuttel,Andrew Wong,Alan F. Wright,Wei Zhao,M. Carola Zillikens,Damiano Baldassarre,Beverley Balkau,Stefania Bandinelli,Carsten A. Böger,Dorret I. Boomsma,Claude Bouchard,Marcel Bruinenberg,Daniel I. Chasman,Yii-Der Ida Chen,Peter S. Chines,Richard S. Cooper,Francesco Cucca,Daniele Cusi,Ulf de Faire,Luigi Ferrucci,Paul W. Franks,Philippe Froguel,Penny Gordon-Larsen,Hans-Jörgen Grabe,Vilmundur Gudnason,Christopher A. Haiman,Caroline Hayward,Kristian Hveem,Andrew D. Johnson,Wouter Jukema,Sharon L.R. Kardia,Mika Kivimäki,Jaspal S. Kooner,Diana Kuh,Markku Laakso,Terho Lehtimäki,Loic Le Marchand,Winfried März,Mark I. McCarthy,Andres Metspalu,Andrew P. Morris,Claes Ohlsson,Lyle J. Palmer,Gerard Pasterkamp,Oluf Pedersen,Annette Peters,Ulrike Peters,Ozren Polasek,Bruce M. Psaty,Lu Qi,Rainer Rauramaa,Blair H. Smith,Thorkild I. A. Sørensen,Konstantin Strauch,Henning Tiemeier,Elena Tremoli,Pim van der Harst,Henrik Vestergaard,Peter Vollenweider,Nicholas J. Wareham,David R. Weir,John Whitfield,James F. Wilson,Jessica Tyrrell,Timothy M. Frayling,Inês Barroso,Michael Boehnke,Panagiotis Deloukas,Caroline S. Fox,Joel N. Hirschhorn,David J. Hunter,Tim D. Spector,David P. Strachan,Cornelia M. van Duijn,Iris M. Heid,Karen L. Mohlke,Jonathan Marchini,Ruth J. F. Loos,Tuomas O. Kilpeläinen,Ching-Ti Liu,Ingrid B. Borecki,Kari E. North,L. Adrienne Cupples +316 more
TL;DR: In this paper, the authors used GWAS data from 51,080 current smokers and 190,178 nonsmokers (87% European descent) to identify loci influencing BMI and central adiposity, measured as waist circumference and waist-to-hip ratio both adjusted for BMI.
Journal ArticleDOI
Separating the Mechanism-Based and Off-Target Actions of Cholesteryl Ester Transfer Protein Inhibitors With CETP Gene Polymorphisms
Reecha Sofat,Aroon D. Hingorani,Liam Smeeth,Steve E. Humphries,Philippa J. Talmud,Jackie A. Cooper,Tina Shah,Manjinder S. Sandhu,Sally L. Ricketts,S. Matthijs Boekholdt,S. Matthijs Boekholdt,Nicholas J. Wareham,Kay-Tee Khaw,Meena Kumari,Mika Kivimäki,Michael Marmot,Folkert W. Asselbergs,Pim van der Harst,Robin P. F. Dullaart,Gerjan Navis,Dirk J. van Veldhuisen,Wiek H. van Gilst,John F. Thompson,Pamela A. McCaskie,Lyle J. Palmer,Marcello Arca,Fabiana Quagliarini,Carlo Gaudio,François Cambien,Viviane Nicaud,Odette Poirer,Vilmundur Gudnason,Aaron Isaacs,Jacqueline C.M. Witteman,Cornelia M. van Duijn,Michael J. Pencina,Ramachandran S. Vasan,Ralph B. D'Agostino,Jose M. Ordovas,Tricia Li,Sakari Kakko,Heikki Kauma,Markku J. Savolainen,Y. Antero Kesäniemi,A. Sandhofer,Bernhard Paulweber,José V. Sorlí,Akimoto Goto,Shinji Yokoyama,Kenji Okumura,Benjamin D. Horne,Chris J. Packard,Dilys J. Freeman,Ian Ford,Naveed Sattar,Valerie McCormack,Debbie A Lawlor,Shah Ebrahim,George Davey Smith,John J.P. Kastelein,John E. Deanfield,Juan P. Casas,Juan P. Casas +62 more
TL;DR: In this paper, the effect of single-nucleotide polymorphisms and torcetrapib treatment on lipid fractions, blood pressure, and electrolytes in up to 67 687 individuals from genetic studies and 17 911 from randomized trials was compared.
Journal ArticleDOI
Minireview Mechanisms by Which the Metabolic Syndrome and Diabetes Impair Memory
TL;DR: How diabetes and the biological changes that occur with diabetes such as hyperglycemia, changes in insulin concentration, hypertension, and changes in lipid levels might lead to alterations in cognitive functioning is examined, with an emphasis on the mechanisms leading to changes in memory.