M
Michael Goggins
Researcher at Johns Hopkins University
Publications - 378
Citations - 52451
Michael Goggins is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 111, co-authored 358 publications receiving 45785 citations. Previous affiliations of Michael Goggins include Johns Hopkins University School of Medicine & Fred Hutchinson Cancer Research Center.
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Journal ArticleDOI
A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts
Simeon Springer,Yuxuan Wang,Marco Dal Molin,David L. Masica,Yuchen Jiao,Isaac Kinde,Amanda L. Blackford,Siva P. Raman,Christopher L. Wolfgang,Tyler M. Tomita,Noushin Niknafs,Christopher Douville,Janine Ptak,Lisa Dobbyn,Peter J. Allen,David S. Klimstra,Mark A. Schattner,C. Max Schmidt,Michele T. Yip-Schneider,Oscar W. Cummings,Randall E. Brand,Herbert J. Zeh,Aatur D. Singhi,Aldo Scarpa,Roberto Salvia,Giuseppe Malleo,Giuseppe Zamboni,Massimo Falconi,Jin-Young Jang,Sun Whe Kim,Wooil Kwon,Seung-Mo Hong,Ki Byung Song,Song Cheol Kim,Niall Swan,Jean Murphy,Justin Geoghegan,William R. Brugge,Carlos Fernandez-del Castillo,Mari Mino-Kenudson,Richard D. Schulick,Barish H. Edil,Volkan Adsay,Jorge Paulino,Jeanin E. van Hooft,Shinichi Yachida,Satoshi Nara,Nobuyoshi Hiraoka,Kenji Yamao,Susuma Hijioka,Schalk Van der Merwe,Michael Goggins,Marcia I. Canto,Nita Ahuja,Kenzo Hirose,Martin A. Makary,Matthew J. Weiss,John L. Cameron,Meredith E. Pittman,James R. Eshleman,Luis A. Diaz,Nickolas Papadopoulos,Kenneth W. Kinzler,Rachel Karchin,Ralph H. Hruban,Bert Vogelstein,Anne Marie Lennon +66 more
TL;DR: A panel of molecular markers and clinical features that show promise for the accurate classification of cystic neoplasms of the pancreas and identification of cysts that require surgery are identified.
Journal Article
Discovery of Novel Targets for Aberrant Methylation in Pancreatic Carcinoma Using High-Throughput Microarrays
Norihiro Sato,Noriyoshi Fukushima,Anirban Maitra,Hiroyuki Matsubayashi,Charles J. Yeo,John L. Cameron,Ralph H. Hruban,Michael Goggins +7 more
TL;DR: A substantial number of genes are induced by 5Aza-dC treatment of pancreatic cancer cells, and many of them may represent novel targets for aberrant methylation in pancreatic carcinoma.
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NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 1.2020.
Mary B. Daly,Robert Pilarski,Matthew B. Yurgelun,Michael Berry,Saundra S. Buys,Patricia I. Dickson,Susan M. Domchek,Ahmed Elkhanany,Susan Hatters Friedman,Judy Garber,Michael Goggins,Mollie L. Hutton,Seema A. Khan,Catherine Klein,Wendy Kohlmann,Allison W. Kurian,Christine Laronga,Jennifer K. Litton,Julie S. Mak,Carolyn S. Menendez,Sofia D. Merajver,Barbara S. Norquist,Kenneth Offit,Tuya Pal,Holly J. Pederson,Gwen Reiser,Kristen M. Shannon,Kala Visvanathan,Jeffrey N. Weitzel,Myra J. Wick,Kari B. Wisinski,Mary A. Dwyer,Susan Darlow +32 more
TL;DR: These NCCN Guidelines Insights summarize the panel's discussion and most recent recommendations regarding criteria for high-penetrance genes associated with breast and ovarian cancer beyond BRCA1/2, pancreas screening and genesassociated with pancreatic cancer, genetic testing for the purpose of systemic therapy decision-making, and testing for people with Ashkenazi Jewish ancestry.
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Mesothelin-specific CD8+ T Cell Responses Provide Evidence of In Vivo Cross-Priming by Antigen-Presenting Cells in Vaccinated Pancreatic Cancer Patients
Amy Morck Thomas,Lynn M. Santarsiero,Eric R. Lutz,Todd D. Armstrong,Yi-Cheng Chen,Lan Qing Huang,Daniel A. Laheru,Michael Goggins,Ralph H. Hruban,Elizabeth M. Jaffee +9 more
TL;DR: The consistent induction of CD8+ T cell responses to multiple HLA-A2, A3, and A24-restricted mesothelin epitopes exclusively in the three patients with vaccine-induced DTH responses is reported.
Journal Article
Discovery of New Markers of Cancer through Serial Analysis of Gene Expression Prostate Stem Cell Antigen Is Overexpressed in Pancreatic Adenocarcinoma
Pedram Argani,Christophe Rosty,Robert E. Reiter,Robb E. Wilentz,Selva R. Murugesan,Steven D. Leach,Byungwoo Ryu,Halcyon G. Skinner,Michael Goggins,Elizabeth M. Jaffee,Charles J. Yeo,John L. Cameron,Scott E. Kern,Ralph H. Hruban +13 more
TL;DR: PSCA is a novel tumor marker for pancreatic carcinoma that has potential diagnostic and therapeutic implications and establishes the validity of analyses of SAGE databases to identify novel tumor markers.