Michel Goedert

TL;DR: This is the first example of the successful generation of iNs from skin cells retrieved post-mortem, which affects both protein function and alternative mRNA splicing in frontotemporal dementia and parkinsonism linked to chromosome 17.

TL;DR: The dopamine receptor antagonist fluphenazine decanoate, when administered for a total period of 10 months, produced a large increase in neurotensin-like immunoreactivity in dopamine-rich brain areas, such as the nucleus accumbens, the striatum and the frontal cortex, providing further evidence in favour of a functional interaction between neurotens in and dopamine in the central nervous system.

TL;DR: An overview of Tau filaments and their positron emission tomography ligands is provided to conclude that the pathological pathway is central to the development of all cases of disease, even if there are multiple reasons for Tau assembly.

TL;DR: In this article, the authors compared the abilities of brain extracts from multiple system atrophy (MSA) and Parkinson's disease (PD) patients to induce neuronal α-synuclein assembly and neurodegeneration following intracerebral injection in heterozygous mice transgenic for human mutant A53T.

TL;DR: It is concluded that they involve a small population of neurons, sensitive to short-term NGF deprivation whereas the majority of the neurons can withstand deprivation for up to 48 h without sustaining irreversible damage.