N. Lackner

TL;DR: A genome-wide association study of lithium response in 2,563 patients collected by 22 participating sites from the International Consortium on Lithium Genetics (ConLiGen); the largest attempted so far finds a single locus of four linked SNPs on chromosome 21 met genome- wide significance criteria for association with lithium response.

TL;DR: A two-stage meta-analysis of GWAS of bipolar disorder patients and controls revealed genome-wide significant associations at two novel loci, adding to a growing list of common autosomal variants involved in BD and illustrating the power of comparing well-characterized cases to an excess of controls in GWAS.

TL;DR: The first preliminary report of the BIPFAT study is presented, which explored shared hypothesized pathophysiological pathways between being overweight and having BD.

TL;DR: Euthymic bipolar adults exhibit peripheral evidence of a disturbed biosignature of oxidative stress and antioxidative defense as well as males with concurrent metabolic disorders with concurrent overweight or obesity and/or comorbid metabolic syndrome.

TL;DR: In bipolar individuals, (abdominal) obesity was significantly associated with a poor cognitive performance and associations with measures of verbal learning and memory were found; in bipolar males, associations with poor performance in the TMT-A/B and in the Stroop interference task were demonstrated.