P
Peter Pickkers
Researcher at Radboud University Nijmegen
Publications - 551
Citations - 24686
Peter Pickkers is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Sepsis & Intensive care. The author has an hindex of 70, co-authored 501 publications receiving 17971 citations. Previous affiliations of Peter Pickkers include Radboud University Nijmegen Medical Centre & Waikato Hospital.
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Journal ArticleDOI
Relationships Between Systemic Inflammation, Intestinal Damage and Postoperative Organ Dysfunction in Adults Undergoing Low-Risk Cardiac Surgery.
Quirine L.M. Habes,Niels Kant,Remi Beunders,Roger van Groenendael,Jelle Gerretsen,Matthijs Kox,Peter Pickkers +6 more
TL;DR: In this article , the authors measured circulating levels of the intestinal damage marker intestinal fatty acid binding protein (I-FABP) and of the inflammatory cytokines tumour necrosis factor (TNF)-α, interleukin (IL)-6, IL-8 and IL-10, and MIP-1β in 180 patients undergoing on-pump cardiac surgery.
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Inflammatory biomarkers to predict the prognosis of acute bacterial and viral infections.
TL;DR: In this article , the authors provide an overview of the value of various inflammatory biomarkers for the prediction of mortality in bacterial and viral infections, and suggest novel strategies for patient stratification and treatment (predictive enrichment) through precision medicine approaches.
Cystatin C is not a reliable marker of residual glomerular filtration rate during continuous renal replacement therapy
TL;DR: In this article, the authors showed that higher levels of cystatin C do not predict the development of acute kidney injury (AKI) nor the need for renal replacement therapy (RRT).
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No elevation of glutathione S-transferase-a1-1 by amiodarone loading in intensive care unit patients with atrial fibrillation.
TL;DR: Amiodarone does not cause elevation of GSTA1-1 as a marker of subclinical liver injury in haemodynamically stable intensive care unit patients with atrial fibrillation, and there was no significant elevation of transaminases or bilirubin during the observation period of 24 hours.
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Potential New Markers of Inflammation-Induced Renal Injury Subside when Endotoxin Tolerance Develops in Humans
Rosalinde Masereeuw,Annelies Draisma,Suzanne Heemskerk,Martijn P.W.J.M. Bouw,Coby M. Laarakkers,Johannes G. van der Hoeven,Peter Pickkers +6 more
TL;DR: Renal injury occurs during repeated endotoxemia and can be predicted by new urinary markers using proteome research, as well as the development of LPS tolerance, which restored renal function when the inflammation-induced renal injury subsided.