P
Peter Pickkers
Researcher at Radboud University Nijmegen
Publications - 551
Citations - 24686
Peter Pickkers is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Sepsis & Intensive care. The author has an hindex of 70, co-authored 501 publications receiving 17971 citations. Previous affiliations of Peter Pickkers include Radboud University Nijmegen Medical Centre & Waikato Hospital.
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Journal ArticleDOI
Lipid-enriched and protein-enriched enteral nutrition limits inflammation in a human endotoxemia model
Matthijs Kox,Tim Lubbers,J. de Haan,JW Greve,Jan C. Pompe,Bart P. Ramakers,Peter Pickkers,Wim A. Buurman +7 more
TL;DR: Enteral administration of lipid-enriched nutrition was previously shown to attenuate inflammation and organ damage via a cholecystokinin-mediated vagovagal reflex in animal studies, and this proof-of-principle study investigates the immunomodulatory potential of enteral lipid- enriched and protein-en enriched nutrition during experimental human endotoxemia.
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Sustainability of clinical pathway guided care in cardiac surgery ICU patients; 9-years experience in over 7500 patients
TL;DR: The use of a CP for all post-operative cardiac surgery patients in the ICU is sustainable, and while more complex patients were treated according to the CP, clinical outcome improved in the CP group.
Journal ArticleDOI
0900. Effects of oxygen status on the innate immune response in humans in vivo
Dorien Kiers,Aaron John,Emmy Janssen,G.J. Scheffer,H. van der Hoeven,Peter Pickkers,Matthijs Kox +6 more
TL;DR: The interplay between oxygen status adjustment and the innate immune response in humans in vivo has not been investigated and hypoxia and hyperoxia could be cheap, non-pharmacological,non-invasive treatment modalities to modulate inflammatory conditions.
Journal Article
Calcitonin gene-related peptide induced vasodilation does not depend on the activation of potassium channels in man
Journal ArticleDOI
Etiologies and Outcomes of Acute Respiratory Failure in Solid Organ Transplant Recipients: Insight Into the EFRAIM Multicenter Cohort.
Jonathan Messika,Michael Darmon,Hervé Mal,Peter Pickkers,Marcio Soares,Emmanuel Canet,Jordi Rello,Philippe R. Bauer,Andry Van de Louw,Virginie Lemiale,Fabio Silvio Taccone,Ignacio Martin Loeches,Peter Schellongowski,Sangeeta Mehta,Massimo Antonelli,Achille Kouatchet,Andreas Barratt-Due,Miia Valkonen,Fabrice Bruneel,Frédéric Pène,Victoria Metaxa,Anne Sophie Moreau,Gastón Burghi,Luca Montini,François Barbier,Lene B. Nielsen,Djamel Mokart,Sylvie Chevret,Lara Zafrani,Elie Azoulay,Efraim investigators +30 more
TL;DR: ICU management of hypoxemic acute respiratory failure in SOT recipients translated into a low ICU mortality rate, whatever the transplanted organ or the acute respiratory fail cause.