P
Peter Pickkers
Researcher at Radboud University Nijmegen
Publications - 551
Citations - 24686
Peter Pickkers is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Sepsis & Intensive care. The author has an hindex of 70, co-authored 501 publications receiving 17971 citations. Previous affiliations of Peter Pickkers include Radboud University Nijmegen Medical Centre & Waikato Hospital.
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Journal ArticleDOI
Kinetics of Neutrophil Subsets in Acute, Subacute, and Chronic Inflammation.
Suzanne H Bongers,Na Chen,Erinke van Grinsven,Selma van Staveren,Marwan Hassani,Roy Spijkerman,Lilian Hesselink,Adèle T. Lo Tam Loi,Corneli van Aalst,Guus P. Leijte,Matthijs Kox,Peter Pickkers,Falco Hietbrink,Luke P. H. Leenen,Leo Koenderman,Nienke Vrisekoop +15 more
TL;DR: In this paper, the changes in kinetics of neutrophils phenotypes in inflammatory conditions were studied, characterized by an increase in CD16dim bands and CD62Llow bands during acute inflammation.
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The challenge of Clostridium difficile infection: Overview of clinical manifestations, diagnostic tools and therapeutic options
TL;DR: The concurrent increase in multiresistant colonisation and increasing numbers of asymptomatic carriers of C. difficile will lead to an increase of the situation in which patients with severe infections, treated with broad-spectrum antibiotics, will develop concurrent severe CDI.
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Lysine methyltransferase G9a is an important modulator of trained immunity.
Vera P. Mourits,Jelmer H. van Puffelen,Boris Novakovic,Mariolina Bruno,Anaisa V. Ferreira,Anaisa V. Ferreira,Rob J.W. Arts,Laszlo Groh,Tania O Crișan,Jelle Zwaag,Elisa Jentho,Elisa Jentho,Matthijs Kox,Peter Pickkers,Frank L. van de Veerdonk,Sebastian Weis,Egbert Oosterwijk,Sita H. Vermeulen,Mihai G. Netea,Mihai G. Netea,Leo A. B. Joosten,Leo A. B. Joosten +21 more
TL;DR: In this paper, the role of Histone methyltransferase G9a in the induction of trained immunity, a de facto innate immune memory, and its effects in non-muscle-invasive bladder cancer (NMIBC) patients treated with intravesical Bacillus Calmette-Guerin (BCG).
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Body Mass Index and Mortality in Coronavirus Disease 2019 and Other Diseases: A Cohort Study in 35,506 ICU Patients.
Emma J. Kooistra,Sylvia Brinkman,Peter H. J. van der Voort,Peter H. J. van der Voort,Nicolette F. de Keizer,Dave A. Dongelmans,Matthijs Kox,Peter Pickkers +7 more
TL;DR: In this paper, the authors investigated the relationship between body mass index and inhospital mortality in critically ill patients and in cohorts of ICU patients with non-severe acute respiratory syndrome coronavirus 2 viral pneumonia, bacterial pneumonia, and multiple trauma.
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The Role of Outcome Expectancies for a Training Program Consisting of Meditation, Breathing Exercises, and Cold Exposure on the Response to Endotoxin Administration: A Proof-Of-Principle Study
TL;DR: This proof-of-principle study provides first indications for potential innovative treatments to change immune-modulating responses by means of psychological mechanisms and may be used for predicting training responses and potentiate their effects by Means of optimism-inducing interventions in patients with immune-mediated rheumatic conditions.