P
Peter Pickkers
Researcher at Radboud University Nijmegen
Publications - 551
Citations - 24686
Peter Pickkers is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Sepsis & Intensive care. The author has an hindex of 70, co-authored 501 publications receiving 17971 citations. Previous affiliations of Peter Pickkers include Radboud University Nijmegen Medical Centre & Waikato Hospital.
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Journal ArticleDOI
Pooled Population Pharmacokinetic Analysis for Exploring Ciprofloxacin Pharmacokinetic Variability in Intensive Care Patients
Tingjie Guo,Alan Abdulla,Birgit C. P. Koch,J. G. Coen van Hasselt,Henrik Endeman,Jeroen Schouten,Paul W. G. Elbers,Roger J. M. Brüggemann,Reinier M. van Hest,Luca F. Roggeveen,Lucas M. Fleuren,Nicole G. M. Hunfeld,Tim M J Ewoldt,Anouk E. Muller,Annemieke Dijkstra,Dylan W. de Lange,Emilie M Gieling,Peter Pickkers,Jaap ten Oever +18 more
TL;DR: In this paper , a pooled population pharmacokinetic (PK) analysis of ciprofloxacin after intravenous administration using individual patient data from three studies was performed.
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Gender-specific differences in outcome after trauma may be explained by differences in immunity
TL;DR: This theory supports the currently prevailing idea that an adequate proinflammatory cytokine response is of benefit, rather than harmful, especially after the initial resuscitation phase of trauma, and may account for the shorter ICU stay observed in women.
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Pharmacokinetics, safety and tolerability of human recombinant alkaline phosphatase in healthy volunteers
TL;DR: A phase I clinical trial is conducted to evaluate tolerability, safety and pharmacokinetics of recAP in healthy volunteers.
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Carboxyhemoglobin levels during human inflammation
TL;DR: It is illustrated that infl ammation does increase CO in humans in vivo, and Cove and Pinsky’s claim that an increase of CO is due to an increase in inhalation is unlikely.
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Safety, Tolerability and Plasmodium Falciparum Transmission-Reducing Activity of Monoclonal Antibody TB31F: An Open-Label, First-in-Human, Trial in Healthy Malaria-Naïve Adults
Saskia C. van der Boor,Merel Smit,Stijn W van Beek,Jordache Ramjith,Karina Teelen,Marga van de Vegte‑Bolmer,Geert-Jan van Gemert,Peter Pickkers,Yimin Wu,Emily Locke,Shwu-Maan. Lee,C. Richter King,Ashley J. Birkett,Kazutoyo Miura,Morolayo A. Ayorinde,Robert W. Sauerwein,Rob ter Heine,Christian F. Ockenhouse,Teun Bousema,Matthijs M. Jore,Matthew B. B. McCall +20 more