P
Peter Pickkers
Researcher at Radboud University Nijmegen
Publications - 551
Citations - 24686
Peter Pickkers is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Sepsis & Intensive care. The author has an hindex of 70, co-authored 501 publications receiving 17971 citations. Previous affiliations of Peter Pickkers include Radboud University Nijmegen Medical Centre & Waikato Hospital.
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Journal ArticleDOI
Age Moderates the Effect of Obesity on Mortality Risk in Critically Ill Patients With COVID-19: A Nationwide Observational Cohort Study*
Corstiaan A. den Uil,Fabian Termorshuizen,Wim J. R. Rietdijk,Roos S G Sablerolles,H. M. van der Kuy,Lenneke E M Haas,Peter H. J. van der Voort,Dylan W. de Lange,Peter Pickkers,Nicolette F. de Keizer +9 more
TL;DR: In this article , a nationwide registry analysis of critically ill patients with COVID-19 registered in the National Intensive Care Evaluation registry showed that a higher BMI may be favorably associated with a lower mortality among those less than 45 years old.
Journal ArticleDOI
How can you mend a broken heart
TL;DR: The results suggest that survival is better, compared to both placebo and dobutamine, and levosimendan should be considered a first-line therapy for critically ill patients with low cardiac output states.
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Risk factors for the deterioration of oxygenation ratio in ventilated intensive care unit patients: a retrospective cohort study.
Ilma W.F. Fick,Myrthe M. Tijdink,F. J. J. Halbertsma,Johannes G. van der Hoeven,Peter Pickkers +4 more
TL;DR: In patients treated with a mean tidal volume of 7.9 mL/kg, controlled ventilation is a major risk factor and lung injury exacerbates during mechanical ventilation.
Journal ArticleDOI
The role of obesity and plasma adipocytokines in immune dysregulation in sepsis patients
Aline H. de Nooijer,Nikolaos Antonakos,D. Markopoulou,Inge Grondman,Matthijs Kox,Peter Pickkers,Evangelos J. Giamarellos-Bourboulis,Mihai G. Netea +7 more
TL;DR: In this paper , the authors investigated the association between obesity, circulating adipocytokine concentrations, immune dysregulation, and outcome in sepsis patients and found that resistin is associated with immunological endotypes, with the highest levels found in hyperinflammatory patients (P < 0.001).
Journal ArticleDOI
Personalised immunotherapy in sepsis: a scoping review protocol
Marleen A. Slim,Niels van Mourik,Joanna C. Dionne,Simon Oczkowski,Mihai G. Netea,Peter Pickkers,Evangelos J. Giamarellos-Bourboulis,Marcella C.A. Müller,T. van der Poll,W. Joost Wiersinga,Alexander P.J. Vlaar,Lonneke A. van Vught +11 more
TL;DR: This scoping review provides a comprehensive overview of current available literature on immunostimulatory and immunosuppressive therapies against sepsis and describes and summarises current literature evaluating immunotherapy in adult patients with sepsi.