P
Peter Pickkers
Researcher at Radboud University Nijmegen
Publications - 551
Citations - 24686
Peter Pickkers is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Sepsis & Intensive care. The author has an hindex of 70, co-authored 501 publications receiving 17971 citations. Previous affiliations of Peter Pickkers include Radboud University Nijmegen Medical Centre & Waikato Hospital.
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Journal ArticleDOI
Reduced rate of MDROs after introducing ‘water-free patient care’ on a large intensive care unit in the Netherlands
Joost Hopman,R Bos,Andreas Voss,Eva Kolwijck,Patrick D. J. Sturm,Peter Pickkers,Alma Tostmann,Hvd Hoeven +7 more
TL;DR: Sinks and the proximity of water in the patient zone are associated with outbreaks and environmental contamination of the patient surroundings is considered of importance in acquiring hospital-associated infections.
Journal ArticleDOI
The influence of hypoxia on platelet function and plasmatic coagulation during systemic inflammation in humans in vivo.
Dorien Kiers,Rahajeng N. Tunjungputri,Rahajeng N. Tunjungputri,Rowie Borkus,Gert Jan Scheffer,Philip G. de Groot,Philip G. de Groot,Rolf T. Urbanus,André J. A. M. van der Ven,Peter Pickkers,Quirijn de Mast,Matthijs Kox +11 more
TL;DR: Hypoxia attenuates the endotoxemia-induced increases in platelet–monocyte formation and platelet reactivity, while leaving parameters of plasmatic coagulation unaffected.
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Prophylactic Haloperidol Effects on Long-term Quality of Life in Critically Ill Patients at High Risk for Delirium: Results of the REDUCE Study.
Paul J T Rood,Marieke Zegers,Arjen J. C. Slooter,Albert Beishuizen,Koen S. Simons,Peter H. J. van der Voort,Meta van der Woude,Peter E. Spronk,Johannes G. van der Hoeven,Peter Pickkers,Mark van den Boogaard +10 more
TL;DR: Prophylactic haloperidol use does not affect long-term quality of life in critically ill patients at high risk for delirium, and several factors, including the modifiable factor number of sedation-induced coma days, are associated with decline in long- term outcomes.
Journal ArticleDOI
Endotoxemia-Induced Release of Pro-inflammatory Mediators Are Associated With Increased Glomerular Filtration Rate in Humans in vivo .
Remi Beunders,Maren J Schütz,Roger van Groenendael,Guus P. Leijte,Matthijs Kox,Lucas T. van Eijk,Peter Pickkers +6 more
TL;DR: Concentrations of pro-inflammatory cytokines, but not blood pressure, are correlated with the endotoxemia-induced increase in GFR in healthy volunteers, suggesting that inflammatory mediators orchestrate the augmented GFR observed in a subgroup of sepsis patients.
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Human in vivo neuroimaging to detect reprogramming of the cerebral immune response following repeated systemic inflammation.
Annemieke M. Peters van Ton,Guus P. Leijte,Gerben M. Franssen,Niklas Bruse,Jan Booij,Janine Doorduin,Mark Rijpkema,Matthijs Kox,Wilson F. Abdo,Peter Pickkers +9 more
TL;DR: In this paper, the trajectory of the immune response systemically and within the brain following repeated lipopolysaccharide (LPS) challenges was examined in healthy volunteers and the systemic immune response was assessed by measuring plasma cytokine levels.