S
Serpil C. Erzurum
Researcher at Cleveland Clinic Lerner Research Institute
Publications - 406
Citations - 34734
Serpil C. Erzurum is an academic researcher from Cleveland Clinic Lerner Research Institute. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 87, co-authored 353 publications receiving 29654 citations. Previous affiliations of Serpil C. Erzurum include Pulmonary Vascular Research Institute & National Institutes of Health.
Papers
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Proceedings ArticleDOI
MicroRNA Processing Is Dysregulated by Mutations Associated with Pulmonary Arterial Hypertension
Proceedings ArticleDOI
Imaging Inflammation With 99mTc-HMPAO SPECT/CT In Asthma
Suphagaphan Ratanamaneechat,Deepa George,Donald R. Neumann,Frank P. DiFilippo,Suzy A.A. Comhair,Mark A. Aronica,Kewal Asosingh,Sudakshina Ghosh,JoAnne Baran,Serpil C. Erzurum +9 more
Journal ArticleDOI
Urinary total conjugated 3-bromotyrosine, asthma severity and exacerbation risk.
Zeneng Wang,Weiling Xu,Suzy A. A. Comhair,Xiaoming Fu,Zhili Shao,Rebecca Bearden,Joe Zein,Eugene R. Bleecker,Mario Castro,Loren C. Denlinger,John V. Fahy,Elliot Israel,Bruce D. Levy,Nizar N. Jarjour,Wendy C. Moore,Sally E. Wenzel,David T. Mauger,Benjamin Gaston,Stanley L. Hazen,Serpil C. Erzurum +19 more
TL;DR: Urinary total conjugated bromotyrosine was independently associated with asthma severity, correlated with the number of asthma exacerbations, and served as a predictor of asthmaacerbation risk over one-year of follow-up.
Posted ContentDOI
A comprehensive SARS-CoV-2-human protein-protein interactome network reveals novel pathobiology and host-targeting therapies for COVID-19
Yadi Zhou,Yun Liu,Shagun Gupta,Mauricio Paramo,Yuan Hou,Chengsheng Mao,Yuan Luo,Julius Judd,Shayne D. Wierbowski,Marta Bertolotti,M Nerkar,Lara Jehi,Nir Drayman,Vlad Nicolaescu,Haley Gula,Savaş Tay,Glenn Randall,John T. Lis,Cédric Feschotte,Serpil C. Erzurum,Feixiong Cheng,Haiyuan Yu +21 more
TL;DR: High-throughput yeast two-hybrid and affinity purification followed by mass spectrometry is used to generate a comprehensive SARS-CoV-2-human protein-protein interactome network consisting of both binary and co-complex interactions, demonstrating the value of large-scale network systems biology approaches for extracting biological insight from complex biological processes.
Journal ArticleDOI
Preclinical 4-Dimensional Functional Lung Imaging and Quantification of Regional Airflow: A New Standard in Lung Function Evaluation in Murine Models.
Kewal Asosingh,Matthew Frimel,Violetta Zlojutro,Dillon Grant,O. Stephens,David Wenger,Andreas Fouras,Frank P. DiFilippo,Serpil C. Erzurum +8 more
TL;DR: The approach reveals repeatable and consistent differences in regional airflow between lung lobes in all models of asthma, suggesting that asthma is characterized by regional airway dysfunctions that are often not detectable in composite measure of lung function.