S
Serpil C. Erzurum
Researcher at Cleveland Clinic Lerner Research Institute
Publications - 406
Citations - 34734
Serpil C. Erzurum is an academic researcher from Cleveland Clinic Lerner Research Institute. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 87, co-authored 353 publications receiving 29654 citations. Previous affiliations of Serpil C. Erzurum include Pulmonary Vascular Research Institute & National Institutes of Health.
Papers
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Journal ArticleDOI
Eosinophil Peroxidase Catalyzed Protein Carbamylation Participates in Asthma.
Zeneng Wang,Joseph A. DiDonato,Jennifer A. Buffa,Suzy A.A. Comhair,Mark A. Aronica,Raed A. Dweik,Nancy A. Lee,James J. Lee,Mary Jane Thomassen,Mani S. Kavuru,Serpil C. Erzurum,Stanley L. Hazen +11 more
TL;DR: EPO-mediated protein carbamylation is promoted during allergen-induced asthma exacerbation, and can both modulate immune responses and trigger a cascade of many of the inflammatory signals present in asthma.
Journal ArticleDOI
Relationship between Right Ventricular Longitudinal Strain, Invasive Hemodynamics, and Functional Assessment in Pulmonary Arterial Hypertension
Jae-Hyeong Park,Jae-Hyeong Park,Kenya Kusunose,Kenya Kusunose,Deborah H Kwon,Margaret M. Park,Margaret M. Park,Serpil C. Erzurum,Serpil C. Erzurum,James D. Thomas,Richard A. Grimm,Brian P. Griffin,Thomas H. Marwick,Thomas H. Marwick,Zoran B. Popović +14 more
TL;DR: RVLS correlates with functional and invasive hemodynamic parameters in PAH patients and decrease of mPAP and PVR as a result of treatment was associated with improvement of RVLS.
Journal ArticleDOI
Benefits of Airway Androgen Receptor Expression in Human Asthma.
Joe Zein,Joe Zein,Jeffrey M. McManus,Nima Sharifi,Serpil C. Erzurum,Serpil C. Erzurum,Nadzeya Marozkina,Timothy Lahm,Olivia K Giddings,Michael D. Davis,Mark D. DeBoer,Suzy A. A. Comhair,Suzy A. A. Comhair,Peter Bazeley,Peter Bazeley,Hyun Jo Kim,William W. Busse,William J. Calhoun,Mario Castro,Kian Fan Chung,John V. Fahy,John V. Fahy,Elliot Israel,Nizar N. Jarjour,Bruce D. Levy,David T. Mauger,Wendy C. Moore,Victor E. Ortega,Michael C. Peters,Eugene R. Bleecker,Deborah A. Meyers,Yi Zhao,Sally E. Wenzel,Benjamin Gaston +33 more
TL;DR: In this paper, Androgens are potentially beneficial in asthma, but AR (androgen receptor) has not been studied in human airways and its ligands are associated with hum...
Journal ArticleDOI
TRAF4-SMURF2–Mediated DAZAP2 Degradation Is Critical for IL-25 Signaling and Allergic Airway Inflammation
Jarod A. Zepp,Ling Wu,Wen Qian,Wenjun Ouyang,Mark A. Aronica,Serpil C. Erzurum,Xiaoxia Li,Xiaoxia Li +7 more
TL;DR: This study indicates that TRAF4-SMURF2–mediated DAZAP2 degradation is a crucial initiating event for the IL-25 response.
Journal ArticleDOI
Gene expression profile of human airway epithelium induced by hyperoxia in vivo.
Arnaud Chambellan,Paul J. Cruickshank,Patrick McKenzie,Steven B. Cannady,Katalin Szabo,Suzy A.A. Comhair,Serpil C. Erzurum +6 more
TL;DR: The human airway early response to hyperoxia relies predominantly upon induction of cytoprotective chaperones and the ubiquitin-proteasome-dependent protein degradation system to maintain airway homeostatic integrity.