S
Serpil C. Erzurum
Researcher at Cleveland Clinic Lerner Research Institute
Publications - 406
Citations - 34734
Serpil C. Erzurum is an academic researcher from Cleveland Clinic Lerner Research Institute. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 87, co-authored 353 publications receiving 29654 citations. Previous affiliations of Serpil C. Erzurum include Pulmonary Vascular Research Institute & National Institutes of Health.
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Journal ArticleDOI
Asthma Is Associated with a Lower Risk of Sepsis and Sepsis-related Mortality.
TL;DR: Authors' contributions: JGZ, TEL, SCE have made substantial contributions to conception and design and to the analysis and interpretation of data.
Journal ArticleDOI
Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity.
Xingnan Li,Stefano Guerra,Julie G. Ledford,Monica Kraft,Huashi Li,Annette T. Hastie,Mario Castro,Loren C. Denlinger,Serpil C. Erzurum,John V. Fahy,Benjamin Gaston,Elliot Israel,Nizar N. Jarjour,Bruce D. Levy,David T. Mauger,Wendy C. Moore,Joe Zein,Naftali Kaminski,Sally E. Wenzel,Prescott G. Woodruff,Deborah A. Meyers,Eugene R. Bleecker +21 more
TL;DR: Low CC16 mRNA expression levels in BEC were significantly associated with asthma susceptibility and asthma severity, high systemic corticosteroids use, high retrospective and prospective asthma exacerbations, and low pulmonary function.
Journal Article
Nitric oxide synthase in the human airway epithelium.
Journal ArticleDOI
Low levels of nitric oxide promotes heme maturation into several hemeproteins and is also therapeutic
Arnab Ghosh,Mamta P. Sumi,Blair Tupta,Toshihiro Okamoto,Kulwant S. Aulak,Masato Tsutsui,Hiroaki Shimokawa,Serpil C. Erzurum,Dennis J. Stuehr +8 more
TL;DR: In this paper , the effects of low NO levels on heme-maturation of hemoglobin and myoglobin were investigated in all three nitric oxide synthases (iNOS, nNOS and eNOS) and Myeloperoxidase (MPO).
Journal ArticleDOI
Single-cell transcriptomic profile of human pulmonary artery endothelial cells in health and pulmonary arterial hypertension
Kewal Asosingh,Suzy A.A. Comhair,Lori Mavrakis,Weiling Xu,Dean J. Horton,Ian A. Taylor,Svyatoslav Tkachenko,Bo Hu,Serpil C. Erzurum +8 more
TL;DR: In this paper, single-cell RNA sequencing technology was used to decipher the cellular heterogeneity among PAEC in the human pulmonary arteries isolated from explanted lungs from three patients with PAH undergoing lung transplantation and three healthy donor lungs not utilized for transplantation.