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Serpil C. Erzurum
Researcher at Cleveland Clinic Lerner Research Institute
Publications - 406
Citations - 34734
Serpil C. Erzurum is an academic researcher from Cleveland Clinic Lerner Research Institute. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 87, co-authored 353 publications receiving 29654 citations. Previous affiliations of Serpil C. Erzurum include Pulmonary Vascular Research Institute & National Institutes of Health.
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Journal ArticleDOI
Natural killer cell-mediated inflammation resolution is disabled in severe asthma.
Melody G. Duvall,Melody G. Duvall,Cindy Barnig,Manuela Cernadas,Isabell Ricklefs,Nandini Krishnamoorthy,Nicole L. Grossman,Nirav R. Bhakta,John V. Fahy,Eugene R. Bleecker,Mario Castro,Serpil C. Erzurum,Benjamin Gaston,Nizar N. Jarjour,David T. Mauger,Sally E. Wenzel,Suzy A.A. Comhair,Andrea M. Coverstone,Merritt L. Fajt,Annette T. Hastie,Mats W. Johansson,Michael C. Peters,Brenda R. Phillips,Elliot Israel,Bruce D. Levy +24 more
TL;DR: The findings indicate that the immunology of the severe asthma airway is characterized by decreased NK cell cytotoxicity with increased numbers of target leukocytes, which is exacerbated by corticosteroids that further disable NK cell function.
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High levels of nitric oxide in individuals with pulmonary hypertension receiving epoprostenol therapy
TL;DR: No may be a useful noninvasive marker of pulmonary hypertension severity and response to prostacyclin therapy and may serve as a sensitive and specific marker of disease progression and/or severity.
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Surfactant suppresses NF-kappa B activation in human monocytic cells.
TL;DR: Results are the first to suggest that surfactant's suppressive effects on inflammatory cytokine production may involve transcriptional regulation through inhibition of NF-kappa B activation.
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Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma
Mark D. DeBoer,Brenda R. Phillips,David T. Mauger,Joe Zein,Serpil C. Erzurum,Anne M. Fitzpatrick,Benjamin Gaston,Ross Myers,Kristie R. Ross,James F. Chmiel,Min Jie Lee,John V. Fahy,Michael C. Peters,Ngoc P. Ly,Sally E. Wenzel,Merritt L. Fajt,Fernando Holguin,Wendy C. Moore,Stephen P. Peters,Deborah A. Meyers,Eugene R. Bleecker,Mario Castro,Andrea M. Coverstone,Leonard B. Bacharier,Nizar N. Jarjour,Ronald L. Sorkness,Sima K. Ramratnam,Anne Marie Irani,Elliot Israel,Bruce D. Levy,Wanda Phipatanakul,Jonathan M. Gaffin,W. Gerald Teague +32 more
TL;DR: These results support beneficial effects of androgens on lung function and symptom control and weak deleterious effects of estradiol on lungfunction in children with asthma.
Journal ArticleDOI
Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report.
Serpil C. Erzurum,Sharon Rounds,Troy Stevens,Micheala A. Aldred,Jason M. Aliotta,Stephen L. Archer,Kewal Asosingh,Robert S. Balaban,Natalie N. Bauer,Jahar Bhattacharya,Harm Jan Bogaard,Gaurav Choudhary,Gerald W. Dorn,Raed A. Dweik,Karen A. Fagan,Michael B. Fallon,Toren Finkel,Mark W. Geraci,Mark T. Gladwin,Paul M. Hassoun,Marc Humbert,Naftali Kaminski,Steven M. Kawut,Joseph Loscalzo,Donald M. McDonald,Ivan F. McMurtry,John H. Newman,Mark R. Nicolls,Marlene Rabinovitch,J. Shizuru,Masahiko Oka,Peter Polgar,David M. Rodman,Paul T. Schumacker,Kurt R. Stenmark,Rubin M. Tuder,Norbert F. Voelkel,Eugene J. Sullivan,Richard M. Weinshilboum,Mervin C. Yoder,Yingming Zhao,Dorothy B. Gail,Timothy Moore +42 more
TL;DR: A workshop to identify priority areas and strategic goals to enhance and accelerate research that will result in improved understanding of the lung vasculature, translational research needs, and ultimately the care of patients with pulmonary vascular diseases held.