S
Serpil C. Erzurum
Researcher at Cleveland Clinic Lerner Research Institute
Publications - 406
Citations - 34734
Serpil C. Erzurum is an academic researcher from Cleveland Clinic Lerner Research Institute. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 87, co-authored 353 publications receiving 29654 citations. Previous affiliations of Serpil C. Erzurum include Pulmonary Vascular Research Institute & National Institutes of Health.
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Journal ArticleDOI
Primary pulmonary hypertension: update on pathogenesis and novel therapies.
TL;DR: Primary pulmonary hypertension is a progressive and fatal disease that chiefly affects young adults and although its etiology is a mystery, recent research has uncovered several biochemical derangements in this disorder, and new therapies are prolonging survival.
Journal ArticleDOI
Genomics and proteomics of lung disease: conference summary
J. Usha Raj,Constantin F. Aliferis,Richard M. Caprioli,Allen W. Cowley,Peter F. Davies,Mark W. Duncan,David J. Erle,Serpil C. Erzurum,Patricia W. Finn,Harry Ischiropoulos,Naftali Kaminski,Steven R. Kleeberger,George D. Leikauf,James E. Loyd,Thomas R. Martin,Sadis Matalon,Jason H. Moore,John Quackenbush,Tara Sabo-Attwood,Steve D. Shapiro,Jan E. Schnitzer,David A. Schwartz,Lisa M. Schwiebert,Dean Sheppard,Lorraine B. Ware,Scott T. Weiss,J. A. Whitsett,Mark M. Wurfel,Michael A. Matthay +28 more
TL;DR: Genomics is the sequencing and analysis of all genes and transcripts in an organism and Proteomics refers to the analysis of genomes.
No evidence that androgen regulation of pulmonary TMPRSS2 explains sex-discordant COVID-19 outcomes
Mehdi Baratchian,Jeffrey M. McManus,Mike Berk,Fumihiko Nakamura,Serpil C. Erzurum,Sanjay Mukhopadhyay,Judy Drazba,John W. Peterson,B.M. Gaston,Nima Sharifi +9 more
TL;DR: In this article, androgen regulation of pulmonary TMPRSS2, the host co-receptor for SARS-CoV-2, was investigated in the lungs of males compared to females in humans or mice.
Journal ArticleDOI
Angioplasticity in asthma.
Kewal Asosingh,Serpil C. Erzurum +1 more
TL;DR: A recent review as discussed by the authors summarizes the current view of angioplasticity in adult lungs and highlights yet unresolved areas of potential interest, concluding that a pro-angiogenic milieu is not a consequence of, but rather dictates the chronic inflammation of asthma.
Journal ArticleDOI
Development and initial validation of the Asthma Severity Scoring System (ASSESS).
Anne M. Fitzpatrick,Stanley J. Szefler,Stanley J. Szefler,David T. Mauger,Brenda R. Phillips,Loren C. Denlinger,Wendy C. Moore,Ronald L. Sorkness,Sally E. Wenzel,Peter J. Gergen,Eugene R. Bleecker,Mario Castro,Serpil C. Erzurum,John V. Fahy,Benjamin Gaston,Elliot Israel,Bruce D. Levy,Deborah A. Meyers,W. Gerald Teague,Leonard B. Bacharier,Ngoc P. Ly,Wanda Phipatanakul,Kristie R. Ross,Joe Zein,Nizar N. Jarjour +24 more
TL;DR: The Asthma Severity Scoring System (ASSESS) is an objective measure that may be useful in epidemiologic and clinical research studies for quantification of treatment response in individual patients and in phenotypic groups, however, validation studies are warranted.