S
Serpil C. Erzurum
Researcher at Cleveland Clinic Lerner Research Institute
Publications - 406
Citations - 34734
Serpil C. Erzurum is an academic researcher from Cleveland Clinic Lerner Research Institute. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 87, co-authored 353 publications receiving 29654 citations. Previous affiliations of Serpil C. Erzurum include Pulmonary Vascular Research Institute & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
Tracheobronchopathy From Inhaled Corticosteroids
TL;DR: Inhaled corticosteroids have become the mainstay of asthma control and are recommended as an add‐on therapy to long‐acting beta agonists and anticholinergics in moderate to severe COPD with recurrent exacerbations.
Journal ArticleDOI
Visualizing inducible nitric-oxide synthase in living cells with a heme-binding fluorescent inhibitor.
Koustubh Panda,Mamta Chawla-Sarkar,Cecile Santos,Thomas Koeck,Serpil C. Erzurum,John Parkinson,Dennis J. Stuehr +6 more
TL;DR: This work characterized a fluorescent inducible NOS (iNOS) inhibitor called PIF (pyrimidine imidazole FITC) and examined its utility for microscopic imaging of iNOS in living cells, revealing that fluorescent probes like PIF will be valuable for studying iNos cell biology and in understanding the pathophysiology of diseases that involve dysfunctional iN OS expression.
Journal ArticleDOI
Baseline sputum eosinophil+neutrophil subgroups’ clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) Cohort
Annette T. Hastie,David T. Mauger,Loren C. Denlinger,Andrea M. Coverstone,Mario Castro,Serpil C. Erzurum,Nijar Jarjour,Bruce D. Levy,Deborah A. Meyers,Wendy C. Moore,Brenda R. Phillips,Sally E. Wenzel,John V. Fahy,Elliot Israel,Eugene R. Bleecker,Nhlbi Sarp Investigators +15 more
TL;DR: Combined elevated sputum eosinophils+neutrophils in asthma associated with lowest lung function, greater healthcare utilization, and longitudinally, further spirometric loss, implicating cell-cell interactions or overlapping inflammatory pathways while increased eos inophils or neutrophils alone show less effect.
Journal ArticleDOI
Mitochondrial Haplogroups and Risk of Pulmonary Arterial Hypertension.
Samar Farha,Bo Hu,Suzy A.A. Comhair,Joe Zein,Raed A. Dweik,Raed A. Dweik,Serpil C. Erzurum,Serpil C. Erzurum,Micheala A. Aldred,Micheala A. Aldred +9 more
TL;DR: The findings suggest that mitochondrial haplogroups influence risk of PAH and that a vulnerability to PAH may have emerged under the selective enrichment of specific haplog groups that occurred with the migration of populations out of Africa.
Journal ArticleDOI
Novel therapeutic approaches to preserve the right ventricle.
TL;DR: The differences between the RV and LV are summarized and novel therapies targeting the RV are investigated in an attempt to improve right-ventricular adaptation to cardiovascular diseases.