S
Serpil C. Erzurum
Researcher at Cleveland Clinic Lerner Research Institute
Publications - 406
Citations - 34734
Serpil C. Erzurum is an academic researcher from Cleveland Clinic Lerner Research Institute. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 87, co-authored 353 publications receiving 29654 citations. Previous affiliations of Serpil C. Erzurum include Pulmonary Vascular Research Institute & National Institutes of Health.
Papers
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Journal ArticleDOI
Ventricular geometry, strain, and rotational mechanics in pulmonary hypertension.
Sarinya Puwanant,Margaret M. Park,Zoran B. Popović,W.H. Wilson Tang,Samar Farha,Deepa George,Jacqueline Sharp,Jirapa Puntawangkoon,James E. Loyd,Serpil C. Erzurum,James D. Thomas +10 more
TL;DR: Chronic RV pressure overload further influences IVS and LV geometry, which impairs LV torsion and segmental LS and CS, more for the IVS than for the free wall of the LV.
Journal ArticleDOI
Hypoxia Inducible-Factor1α Regulates the Metabolic Shift of Pulmonary Hypertensive Endothelial Cells
Iwona Fijalkowska,Weiling Xu,Suzy A. A. Comhair,Allison J. Janocha,Lori Mavrakis,Balaji Krishnamachary,Lijie Zhen,Thianzi Mao,Amy Richter,Serpil C. Erzurum,Serpil C. Erzurum,Rubin M. Tuder,Rubin M. Tuder +12 more
TL;DR: Findings indicate that alterations of nitric oxide and MnSOD contribute to pathological HIF-1alpha expression and account for lower numbers of mitochondria in IPAH-ECs.
Journal ArticleDOI
Asthma is Different in Women
Joe Zein,Serpil C. Erzurum +1 more
TL;DR: Gender differences in asthma incidence, prevalence and severity have been reported worldwide, and it is suggested that after puberty, asthma becomes more prevalent and severe in women, and is highest in women with early menarche or with multiple gestations.
Journal ArticleDOI
Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data
Wei Wu,Eugene R. Bleecker,Wendy C. Moore,William W. Busse,Mario Castro,Kian Fan Chung,William J. Calhoun,Serpil C. Erzurum,Benjamin Gaston,Elliot Israel,Douglas Curran-Everett,Sally E. Wenzel,Sally E. Wenzel +12 more
TL;DR: In this paper, an unsupervised clustering approach was used to identify subphenotypes of asthma by using blood, bronchoscopic, exhaled nitric oxide, and clinical data from the Severe Asthma Research Program.
Journal ArticleDOI
Biochemical Reaction Products of Nitric Oxide as Quantitative Markers of Primary Pulmonary Hypertension
F. Takao Kaneko,Alejandro C. Arroliga,Raed A. Dweik,Suzy A.A. Comhair,Daniel Laskowski,Rita Oppedisano,Mary Jane Thomassen,Serpil C. Erzurum +7 more
TL;DR: NO and oxidant reactions in the lung are related to the increased pulmonary artery pressures in PPH and the findings of the study show that NO and oxidation products are formed through interactions between oxidants and NO.