S
Silvano Sozzani
Researcher at Sapienza University of Rome
Publications - 352
Citations - 47443
Silvano Sozzani is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Chemokine & Chemokine receptor. The author has an hindex of 98, co-authored 335 publications receiving 43598 citations. Previous affiliations of Silvano Sozzani include University of Turin & Brescia University.
Papers
More filters
Journal Article
Thioredoxin specifically cross-desensitizes monocytes to MCP-1.
Sabrina Pagliei,Pietro Ghezzi,Cinzia Bizzarri,Vilma Sabbatini,Giada Frascaroli,Silvano Sozzani,Gianfranco Caselli,Riccardo Bertini +7 more
TL;DR: It is suggested that Trx inhibits monocyte responses to chemokines by acting downstream of the chemokine receptors, since there are high concentrations of circulating Trx in infection and inflammatory diseases, this might act as an inhibitor of monocyte migration in vivo.
Journal ArticleDOI
The effect of Biostim (RU 41.740) on natural killer activity in different mouse organs.
TL;DR: It is shown that NK cells can also be a target of Biostim, and this results can contribute to a better understanding of the mode of action of this immunomodulator.
Journal ArticleDOI
Chronic inflammatory diseases: Do immunological patterns drive the choice of biotechnology drugs? A critical review
Silvano Sozzani,Maria P. Abbracchio,Vito Annese,Silvio Danese,Ornella De Pità,Giovambattista De Sarro,Sabatino Maione,Ignazio Olivieri,Aurora Parodi,Piercarlo Sarzi-Puttini +9 more
TL;DR: The purpose of this analysis is to address the most critical issues raised by the rapid advancements in this field over recent years, and to acknowledge the potentially valuable gains brought about by the increasing availability of these new biologic agents.
Dendritic Cells Production by Myeloid and Plasmacytoid Cutting Edge: Differential Chemokine
TL;DR: This article cites 29 articles, 18 of which you can access for free at: Subscriptions http://jimmunol.org/content/169/12/6673J Immunol€2002; 169:6673-6676; ;References
Up-Regulation of CCR1 and CCR3 and Induction of Chemotaxis to CC Chemokines by IFN-g in Human
Raffaella Bonecchi,Nadia Polentarutti,Walter Luini,Alessandro Borsatti,Sergio Bernasconi,M. Locati,Christine Power,Amanda Proudfoot,Timothy N. C. Wells,Charles R. Mackay,Alberto Mantovani,Silvano Sozzani +11 more
TL;DR: The results suggest that the selectivity of certain chemokines for their target cells may be altered by cytokines produced within an inflammatory context.