S
Silvano Sozzani
Researcher at Sapienza University of Rome
Publications - 352
Citations - 47443
Silvano Sozzani is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Chemokine & Chemokine receptor. The author has an hindex of 98, co-authored 335 publications receiving 43598 citations. Previous affiliations of Silvano Sozzani include University of Turin & Brescia University.
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Journal Article
Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines.
Silvano Sozzani,Federica Sallusto,Walter Luini,Dan Zhou,Lorenzo Piemonti,Paola Allavena,J. Van Damme,Salvatore Valitutti,Antonio Lanzavecchia,Alberto Mantovani +9 more
TL;DR: FMLP, C5a, and the C-C chemokines monocyte chemotactic protein (MCP)-3, MIP-1 alpha/LD78, and RANTES elicited chemotact migration and a rise of intracellular free calcium in dendritic cells, and Chemoattractants were inactive as chemoattractant.
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1,25-Dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells.
Giuseppe Penna,Susana Amuchastegui,Nadia Giarratana,Kenn C. Daniel,Marisa Vulcano,Silvano Sozzani,Luciano Adorini +6 more
TL;DR: Interestingly, 1,25(OH)2D3 inhibited NF-κB p65 phosphorylation and nuclear translocation in M-DCs but not P-DC’s, suggesting a mechanism for the inability of 1, 25(OH), 2D3 to modulate tolerogenic properties in P- DCs.
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The detection and localization of monocyte chemoattractant protein-1 (MCP-1) in human ovarian cancer.
Rupert P. M. Negus,Gordon Stamp,Michele G. Relf,Frances Burke,Saleem T. A. Malik,Sergio Bernasconi,Paola Allavena,Silvano Sozzani,Alberto Mantovani,Frances R. Balkwill +9 more
TL;DR: It is concluded that the macrophage chemoattractant MCP-1 is produced by epithelial ovarian cancer and that the tumor cells themselves are probably a major source.
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Induction of natural killer cell migration by monocyte chemotactic protein−1, −2 and −3
Paola Allavena,Giancarlo Bianchi,Dan Zhou,Jo Van Damme,Petr Jílek,Silvano Sozzani,Alberto Mantovani +6 more
TL;DR: Investigation of the responsiveness of NK cells to the prototypic C‐C chemokine, monocyte chemotactic protein‐1 (MCP‐1) found that it induced migration across filters of interleukin (IL)‐2‐activated NK cells, whereas it was a weak attractant for unstimulated cells.
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Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment.
Cristina Albanesi,Claudia Scarponi,Sabatino Pallotta,Roberta Daniele,Roberta Daniele,Daniela Bosisio,Stefania Madonna,Paola Fortugno,Safiyè Gonzalvo-Feo,Jean-Denis Franssen,Marc Parmentier,Ornella De Pità,Giampiero Girolomoni,Silvano Sozzani +13 more
TL;DR: Chemerin expression specifically marks the early phases of evolving skin psoriatic lesions and is temporally strictly associated with pDC, which support a role for the chemerin/ChemR23 axis in theEarly phases of psoriasis development.