S
Stefan Schwarz
Researcher at Friedrich Loeffler Institute
Publications - 264
Citations - 13947
Stefan Schwarz is an academic researcher from Friedrich Loeffler Institute. The author has contributed to research in topics: Plasmid & Gene. The author has an hindex of 59, co-authored 207 publications receiving 12184 citations. Previous affiliations of Stefan Schwarz include Free University of Berlin & University of Giessen.
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Journal ArticleDOI
A field guide to pandemic, epidemic and sporadic clones of methicillin-resistant Staphylococcus aureus
Stefan Monecke,Geoffrey W. Coombs,Anna C. Shore,David C. Coleman,Patrick Eberechi Akpaka,Michael Borg,Henry Chow,Margaret Ip,Lutz Jatzwauk,Daniel Jonas,Kristina Kadlec,Angela M. Kearns,Frédéric Laurent,Frances G. O'Brien,Julie C. Pearson,Antje Ruppelt,Stefan Schwarz,E. Scicluna,Peter Slickers,Hui-Leen Tan,Stefan Weber,Ralf Ehricht +21 more
TL;DR: A high level of biodiversity among MRSA, especially among strains harbouring SCCmec IV and V elements is shown, and the data indicate a high rate of genetic recombination in MRSA involving SCC elements, bacteriophages or other mobile genetic elements and large-scale chromosomal replacements.
Journal ArticleDOI
Staphylococcus aureus CC398: Host Adaptation and Emergence of Methicillin Resistance in Livestock
Lance B. Price,Marc Stegger,Henrik Hasman,Maliha Aziz,Jesper Larsen,Paal Skytt Andersen,Talima Pearson,Andrew E. Waters,Jeffrey T. Foster,James M. Schupp,John D. Gillece,Elizabeth M. Driebe,Cindy M. Liu,Cindy M. Liu,Burkhard Springer,Irena Zdovc,Antonio Battisti,Alessia Franco,Jacek Żmudzki,Stefan Schwarz,Patrick Butaye,Eric Jouy,Constança Pomba,M. Concepción Porrero,Raymond Ruimy,Tara C. Smith,D. Ashley Robinson,J. Scott Weese,Carmen Sofia Arriola,Fangyou Yu,Frédéric Laurent,Paul Keim,Paul Keim,Robert Skov,Frank Møller Aarestrup +34 more
TL;DR: The results strongly suggest that livestock-associated MRSA CC398 originated in humans as MSSA, which appears to have undergone a rapid radiation in conjunction with the jump from humans to livestock, where it subsequently acquired tetracycline and methicillin resistance.
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Molecular basis of bacterial resistance to chloramphenicol and florfenicol.
TL;DR: This review presents an overview of the different mechanisms responsible for resistance to Cm and Ff with particular focus on the two different types of chloramphenicol acetyltransferases (CATs), specific exporters and multidrug transporters.
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Use of antimicrobial agents in veterinary medicine and food animal production.
TL;DR: An overview of the use of antimicrobial agents in animals for therapeutic, metaphylactic, prophylactic and growth promotion purposes is presented with particular reference to the role of animals as a reservoir of resistance genes or resistant bacterial pathogens which may cause diseases in humans.
Journal ArticleDOI
Clonal spread of methicillin-resistant Staphylococcus pseudintermedius in Europe and North America: an international multicentre study
Vincent Perreten,Kristina Kadlec,Stefan Schwarz,Ulrika Grönlund Andersson,Maria Finn,Christina Greko,Arshnee Moodley,Stephen A. Kania,Linda A. Frank,David A. Bemis,Alessia Franco,Manuela Iurescia,Antonio Battisti,Birgitta Duim,Jaap A. Wagenaar,Engeline van Duijkeren,J. Scott Weese,J. Ross Fitzgerald,Alexandra Rossano,Luca Guardabassi +19 more
TL;DR: Two major clonal MRSP lineages have disseminated in Europe and North America and regardless of their geographical or clonal origin, the isolates displayed resistance to the major classes of antibiotics used in veterinary medicine and thus infections caused by MRSP isolates represent a serious therapeutic challenge.