S
Stephanie A. Rosse
Researcher at Fred Hutchinson Cancer Research Center
Publications - 10
Citations - 878
Stephanie A. Rosse is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Genome-wide association study & Colorectal cancer. The author has an hindex of 9, co-authored 10 publications receiving 770 citations. Previous affiliations of Stephanie A. Rosse include Los Angeles Biomedical Research Institute & University of Washington.
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Journal ArticleDOI
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis
Ulrike Peters,Ulrike Peters,Shuo Jiao,Fredrick R. Schumacher,Carolyn M. Hutter,Carolyn M. Hutter,Aaron K. Aragaki,John A. Baron,Sonja I. Berndt,Stéphane Bézieau,Hermann Brenner,Katja Butterbach,Bette J. Caan,Peter T. Campbell,Christopher S. Carlson,Christopher S. Carlson,Graham Casey,Andrew T. Chan,Jenny Chang-Claude,Stephen J. Chanock,Lin Chen,Gerhard A. Coetzee,Simon G. Coetzee,David V. Conti,Keith R. Curtis,David Duggan,Todd L. Edwards,Charles S. Fuchs,Steven Gallinger,Edward Giovannucci,Stephanie M. Gogarten,Stephen B. Gruber,Robert W. Haile,Tabitha A. Harrison,Richard B. Hayes,Brian E. Henderson,Michael Hoffmeister,John L. Hopper,Thomas J. Hudson,Thomas J. Hudson,David J. Hunter,Rebecca D. Jackson,Sun Ha Jee,Mark A. Jenkins,Wei Hua Jia,Laurence N. Kolonel,Charles Kooperberg,Sébastien Küry,Andrea Z. LaCroix,Cathy C. Laurie,Cecelia A. Laurie,Loic Le Marchand,Mathieu Lemire,David K. Levine,Noralane M. Lindor,Yan Liu,Jing Ma,Karen W. Makar,Keitaro Matsuo,Polly A. Newcomb,Polly A. Newcomb,John D. Potter,John D. Potter,Ross L. Prentice,Conghui Qu,Thomas E. Rohan,Stephanie A. Rosse,Stephanie A. Rosse,Robert E. Schoen,Daniela Seminara,Martha J. Shrubsole,Xiao-Ou Shu,Martha L. Slattery,Darin Taverna,Stephen N. Thibodeau,Cornelia M. Ulrich,Emily White,Emily White,Yong-Bing Xiang,Brent W. Zanke,Yi Xin Zeng,Ben Zhang,Wei Zheng,Li Hsu +83 more
TL;DR: In a large genome-wide association study, polymorphisms close to nucleic acid binding protein 1 (which encodes a DNA-binding protein involved in DNA repair) with colorectal tumor risk and polymorphisms in laminin gamma 1, cyclin D2, and T-box 3 are associated.
Journal ArticleDOI
Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants.
Hongmei Nan,Carolyn M. Hutter,Yi Lin,Eric J. Jacobs,Cornelia M. Ulrich,Cornelia M. Ulrich,Emily White,Emily White,John A. Baron,Sonja I. Berndt,Hermann Brenner,Katja Butterbach,Bette J. Caan,Peter T. Campbell,Christopher S. Carlson,Graham Casey,Jenny Chang-Claude,Stephen J. Chanock,Michelle Cotterchio,David Duggan,Jane C. Figueiredo,Charles S. Fuchs,Edward Giovannucci,Jian Gong,Robert W. Haile,Tabitha A. Harrison,Richard B. Hayes,Michael Hoffmeister,John L. Hopper,Thomas J. Hudson,Thomas J. Hudson,Mark A. Jenkins,Shuo Jiao,Noralane M. Lindor,Mathieu Lemire,Loic Le Marchand,Polly A. Newcomb,Shuji Ogino,Bethann M. Pflugeisen,John D. Potter,John D. Potter,Conghui Qu,Stephanie A. Rosse,Anja Rudolph,Robert E. Schoen,Fredrick R. Schumacher,Daniela Seminara,Martha L. Slattery,Stephen N. Thibodeau,Fridtjof Thomas,Mark D. Thornquist,Greg S. Warnick,Brent W. Zanke,W. James Gauderman,Ulrike Peters,Ulrike Peters,Li Hsu,Li Hsu,Andrew T. Chan +58 more
TL;DR: In this genome-wide investigation of gene × environment interactions, use of aspirin and/or NSAIDs was associated with lower risk of colorectal cancer, and this association differed according to genetic variation at 2 SNPs at chromosomes 12 and 15.
Journal ArticleDOI
Genome-wide association study of colorectal cancer identifies six new susceptibility loci
Fredrick R. Schumacher,Stephanie L. Schmit,Shuo Jiao,Christopher K. Edlund,Hansong Wang,Ben Zhang,Li Hsu,Shu Chen Huang,Christopher P. Fischer,John F. Harju,Gregory Idos,Flavio Lejbkowicz,Frank J. Manion,Kevin McDonnell,Caroline McNeil,Marilena Melas,Hedy S. Rennert,Wei Shi,Duncan C. Thomas,David Van Den Berg,Carolyn M. Hutter,Aaron K. Aragaki,Katja Butterbach,Bette J. Caan,Christopher S. Carlson,Stephen J. Chanock,Keith R. Curtis,Charles S. Fuchs,Manish Gala,Edward L. Giocannucci,Stephanie M. Gogarten,Richard B. Hayes,Brian E. Henderson,David J. Hunter,Rebecca D. Jackson,Laurence N. Kolonel,Charles Kooperberg,Sebastian Kury,Andrea Z. LaCroix,Cathy C. Laurie,Cecelia A. Laurie,Mathiew Lemire,David K. Levine,Jing Ma,Karen W. Makar,Conghui Qu,Darin Taverna,Cornelia M. Ulrich,Cornelia M. Ulrich,Cornelia M. Ulrich,Kana Wu,Suminori Kono,Dee W. West,Sonja I. Berndt,Stéphane Bézieau,Hermann Brenner,Peter T. Campbell,Andrew T. Chan,Jenny Chang-Claude,Gerhard A. Coetzee,David V. Conti,David Duggan,Jane C. Figueiredo,Barbara K. Fortini,Steven Gallinger,W. James Gauderman,Graham G. Giles,Roger C. Green,Robert W. Haile,Tabitha A. Harrison,Michael Hoffmeister,John L. Hopper,Thomas J. Hudson,Eric J. Jacobs,Motoki Iwasaki,Sun Ha Jee,Mark A. Jenkins,Wei Hua Jia,Amit Joshi,Li Li,N. M. Lindor,Keitaro Matsuo,Victor Moreno,Bhramar Mukherjee,Polly A. Newcomb,John D. Potter,Leon Raskin,Leon Raskin,Gad Rennert,Stephanie A. Rosse,Gianluca Severi,Robert E. Schoen,Daniela Seminara,Xiao-Ou Shu,Martha L. Slattery,Shoichiro Tsugane,Emily White,Yong-Bing Xiang,Brent W. Zanke,Wei Zheng,Loic Le Marchand,Graham Casey,Stephen B. Gruber,Ulrike Peters +103 more
TL;DR: Six new susceptibility loci reaching a genome-wide threshold of P<5.0E-08 are described, providing additional insight into the underlying biological mechanisms of colorectal cancer and demonstrating the scientific value of large consortia-based genetic epidemiology studies.
Journal ArticleDOI
Genome-Wide Diet-Gene Interaction Analyses for Risk of Colorectal Cancer
Jane C. Figueiredo,Li Hsu,Carolyn M. Hutter,Yi Lin,Peter T. Campbell,John A. Baron,Sonja I. Berndt,Shuo Jiao,Graham Casey,Barbara K. Fortini,Andrew T. Chan,Michelle Cotterchio,Mathieu Lemire,Steven Gallinger,Tabitha A. Harrison,Loic Le Marchand,Polly A. Newcomb,Martha L. Slattery,Bette J. Caan,Christopher S. Carlson,Brent W. Zanke,Stephanie A. Rosse,Hermann Brenner,Edward Giovannucci,Kana Wu,Jenny Chang-Claude,Stephen J. Chanock,Keith R. Curtis,David Duggan,Jian Gong,Robert W. Haile,Richard B. Hayes,Michael Hoffmeister,John L. Hopper,Mark A. Jenkins,Laurence N. Kolonel,Conghui Qu,Anja Rudolph,Robert E. Schoen,Fredrick R. Schumacher,Daniela Seminara,Deanna L. Stelling,Stephen N. Thibodeau,Mark D. Thornquist,Greg S. Warnick,Brian E. Henderson,Cornelia M. Ulrich,Cornelia M. Ulrich,W. James Gauderman,John D. Potter,John D. Potter,Emily White,Ulrike Peters +52 more
TL;DR: The results identify a novel gene-diet interaction with processed meat for colorectal cancer, highlighting that diet may modify the effect of genetic variants on disease risk, which may have important implications for prevention.
Journal ArticleDOI
Fine Mapping and Identification of BMI Loci in African Americans
Jian Gong,Fredrick R. Schumacher,Unhee Lim,Lucia A. Hindorff,Jeffrey Haessler,Steven Buyske,Christopher S. Carlson,Stephanie A. Rosse,Petra Bůžková,Myriam Fornage,Myron D. Gross,Nathan Pankratz,James S. Pankow,Pamela J. Schreiner,Richard S. Cooper,Georg Ehret,Georg Ehret,C. Charles Gu,Denise K. Houston,Marguerite R. Irvin,Rebecca D. Jackson,Lew Kuller,Brian E. Henderson,Iona Cheng,Lynne R. Wilkens,Mark Leppert,Cora E. Lewis,Rongling Li,Khanh-Dung H. Nguyen,Robert Goodloe,Eric Farber-Eger,Jonathan Boston,Holli H. Dilks,Marylyn D. Ritchie,Jay H. Fowke,Loreall Pooler,Misa Graff,Lindsay Fernández-Rhodes,Barbara Cochrane,Eric Boerwinkle,Charles Kooperberg,Tara C. Matise,Loic Le Marchand,Dana C. Crawford,Christopher A. Haiman,Kari E. North,Ulrike Peters +46 more
TL;DR: Fine mapping in AAs is a powerful approach for both narrowing in on the underlying causal variants in known loci and discovering BMI-related loci.