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Shu Chen Huang
Researcher at University of Michigan
Publications - 8
Citations - 566
Shu Chen Huang is an academic researcher from University of Michigan. The author has contributed to research in topics: Genome-wide association study & Cancer. The author has an hindex of 7, co-authored 8 publications receiving 458 citations. Previous affiliations of Shu Chen Huang include University of Southern California.
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Journal ArticleDOI
Genome-wide association study of colorectal cancer identifies six new susceptibility loci
Fredrick R. Schumacher,Stephanie L. Schmit,Shuo Jiao,Christopher K. Edlund,Hansong Wang,Ben Zhang,Li Hsu,Shu Chen Huang,Christopher P. Fischer,John F. Harju,Gregory Idos,Flavio Lejbkowicz,Frank J. Manion,Kevin McDonnell,Caroline McNeil,Marilena Melas,Hedy S. Rennert,Wei Shi,Duncan C. Thomas,David Van Den Berg,Carolyn M. Hutter,Aaron K. Aragaki,Katja Butterbach,Bette J. Caan,Christopher S. Carlson,Stephen J. Chanock,Keith R. Curtis,Charles S. Fuchs,Manish Gala,Edward L. Giocannucci,Stephanie M. Gogarten,Richard B. Hayes,Brian E. Henderson,David J. Hunter,Rebecca D. Jackson,Laurence N. Kolonel,Charles Kooperberg,Sebastian Kury,Andrea Z. LaCroix,Cathy C. Laurie,Cecelia A. Laurie,Mathiew Lemire,David K. Levine,Jing Ma,Karen W. Makar,Conghui Qu,Darin Taverna,Cornelia M. Ulrich,Cornelia M. Ulrich,Cornelia M. Ulrich,Kana Wu,Suminori Kono,Dee W. West,Sonja I. Berndt,Stéphane Bézieau,Hermann Brenner,Peter T. Campbell,Andrew T. Chan,Jenny Chang-Claude,Gerhard A. Coetzee,David V. Conti,David Duggan,Jane C. Figueiredo,Barbara K. Fortini,Steven Gallinger,W. James Gauderman,Graham G. Giles,Roger C. Green,Robert W. Haile,Tabitha A. Harrison,Michael Hoffmeister,John L. Hopper,Thomas J. Hudson,Eric J. Jacobs,Motoki Iwasaki,Sun Ha Jee,Mark A. Jenkins,Wei Hua Jia,Amit Joshi,Li Li,N. M. Lindor,Keitaro Matsuo,Victor Moreno,Bhramar Mukherjee,Polly A. Newcomb,John D. Potter,Leon Raskin,Leon Raskin,Gad Rennert,Stephanie A. Rosse,Gianluca Severi,Robert E. Schoen,Daniela Seminara,Xiao-Ou Shu,Martha L. Slattery,Shoichiro Tsugane,Emily White,Yong-Bing Xiang,Brent W. Zanke,Wei Zheng,Loic Le Marchand,Graham Casey,Stephen B. Gruber,Ulrike Peters +103 more
TL;DR: Six new susceptibility loci reaching a genome-wide threshold of P<5.0E-08 are described, providing additional insight into the underlying biological mechanisms of colorectal cancer and demonstrating the scientific value of large consortia-based genetic epidemiology studies.
Journal ArticleDOI
Elevated Risk of Prostate Cancer Among Men With Lynch Syndrome
Victoria M. Raymond,Bhramar Mukherjee,Fei Wang,Shu Chen Huang,Elena M. Stoffel,Fay Kastrinos,Fay Kastrinos,Sapna Syngal,Kathleen A. Cooney,Stephen B. Gruber,Stephen B. Gruber +10 more
TL;DR: The cumulative lifetime risk of prostate cancer in individuals with LS is two-fold higher than in the general population and is slightly higher in carriers diagnosed before age 60 years (HR, 2.48; 95% CI, 1.34 to 4.59).
Journal ArticleDOI
Novel Common Genetic Susceptibility Loci for Colorectal Cancer
Stephanie L. Schmit,Christopher K. Edlund,Fredrick R. Schumacher,Jian Gong,Tabitha A. Harrison,Jeroen R. Huyghe,Chenxu Qu,Marilena Melas,David Van Den Berg,Hansong Wang,Stephanie Tring,Sarah J. Plummer,Demetrius Albanes,M. Henar Alonso,Christopher I. Amos,Kristen Anton,Aaron K. Aragaki,Volker Arndt,Elizabeth L. Barry,Sonja I. Berndt,Stéphane Bézieau,Stephanie A. Bien,Amanda Bloomer,Juergen Boehm,Marie-Christine Boutron-Ruault,Marie-Christine Boutron-Ruault,Hermann Brenner,Stefanie Brezina,Daniel D. Buchanan,Daniel D. Buchanan,Katja Butterbach,Bette J. Caan,Peter T. Campbell,Chris S. Carlson,Jose E. Castelao,Andrew T. Chan,Jenny Chang-Claude,Jenny Chang-Claude,Stephen J. Chanock,Iona Cheng,Ya Wen Cheng,Lee Soo Chin,James M. Church,Timothy R. Church,Gerhard A. Coetzee,Michelle Cotterchio,Marcia Cruz Correa,Keith R. Curtis,David Duggan,Douglas F. Easton,Dallas R. English,Edith J. M. Feskens,Rocky Fischer,Liesel M. FitzGerald,Liesel M. FitzGerald,Barbara K. Fortini,Lars G. Fritsche,Lars G. Fritsche,Charles S. Fuchs,Charles S. Fuchs,Manuela Gago-Dominguez,Manish Gala,Steven Gallinger,W. James Gauderman,Graham G. Giles,Graham G. Giles,Edward Giovannucci,Edward Giovannucci,Stephanie M. Gogarten,Clicerio Gonzalez-Villalpando,Elena M. Gonzalez-Villalpando,William M. Grady,Joel K. Greenson,Andrea Gsur,Marc J. Gunter,Christopher A. Haiman,Jochen Hampe,Sophia Harlid,John F. Harju,Richard B. Hayes,Philipp Hofer,Michael Hoffmeister,John L. Hopper,Shu Chen Huang,José María Huerta,Thomas J. Hudson,David J. Hunter,Gregory Idos,Motoki Iwasaki,Rebecca D. Jackson,Eric J. Jacobs,Sun Ha Jee,Mark A. Jenkins,Weihua Jia,Shuo Jiao,Amit Joshi,Laurence N. Kolonel,Suminori Kono,Charles Kooperberg,Vittorio Krogh,Tilman Kuehn,Sébastien Küry,Andrea Z. LaCroix,Cecelia A. Laurie,Flavio Lejbkowicz,Flavio Lejbkowicz,Mathieu Lemire,Heinz-Josef Lenz,David N. Levine,Christopher I. Li,Li Li,Wolfgang Lieb,Yi Lin,Noralane M. Lindor,Yun Ru Liu,Fotios Loupakis,Yingchang Lu,Frank Luh,Jing Ma,Christoph Mancao,Frank J. Manion,Sanford D. Markowitz,Vicente Martín,Koichi Matsuda,Koichi Matsuda,Keitaro Matsuo,Kevin McDonnell,Caroline McNeil,Roger L. Milne,Roger L. Milne,Antonio J. Molina,Bhramar Mukherjee,Neil Murphy,Polly A. Newcomb,Kenneth Offit,Hanane Omichessan,Hanane Omichessan,Domenico Palli,Jesus P. Paredes Cotoré,Julyann Pérez-Mayoral,Paul D.P. Pharoah,John D. Potter,Conghui Qu,Leon Raskin,Gad Rennert,Gad Rennert,Hedy S. Rennert,Bridget M. Riggs,Clemens Schafmayer,Robert E. Schoen,Thomas A. Sellers,Daniela Seminara,Gianluca Severi,Wei Shi,David Shibata,Xiao-Ou Shu,Erin M. Siegel,Martha L. Slattery,Melissa C. Southey,Zsofia K. Stadler,Zsofia K. Stadler,Mariana C. Stern,Sebastian Stintzing,Darin Taverna,Stephen N. Thibodeau,Duncan C. Thomas,Antonia Trichopoulou,Shoichiro Tsugane,Cornelia M. Ulrich,Fränzel J.B. van Duijnhoven,Bethany van Guelpan,Joseph Vijai,Jarmo Virtamo,Stephanie J. Weinstein,Emily White,Aung Ko Win,Alicja Wolk,Michael O. Woods,Anna H. Wu,Kana Wu,Yong-Bing Xiang,Yun Yen,Brent W. Zanke,Brent W. Zanke,Yi Xin Zeng,Ben Zhang,Niha Zubair,Sun-Seog Kweon,Jane C. Figueiredo,Jane C. Figueiredo,Wei Zheng,Loic Le Marchand,Annika Lindblom,Victor Moreno,Ulrike Peters,Graham Casey,Li Hsu,David V. Conti,Stephen B. Gruber +198 more
TL;DR: This article identified 42 loci (P < 5x10−8) associated with risk of colorectal cancer (CRC) and expanded consortium efforts facilitating the discovery of these loci.
Journal ArticleDOI
Risk of colorectal cancer in self-reported inflammatory bowel disease and modification of risk by statin and NSAID use
N. Jewel Samadder,Bhramar Mukherjee,Shu Chen Huang,Jaeil Ahn,Hedy S. Rennert,Joel K. Greenson,Gad Rennert,Stephen B. Gruber +7 more
TL;DR: The objective of this study was to quantify the relative risk of inflammatory bowel disease (IBD) as a risk factor for CRC and to estimate whether this risk may be modified by long‐term use of NSAIDs or statins.
Journal ArticleDOI
A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study.
Stephanie L. Schmit,Fredrick R. Schumacher,Christopher K. Edlund,David V. Conti,Leon Raskin,Flavio Lejbkowicz,Mila Pinchev,Hedy S. Rennert,Mark A. Jenkins,John L. Hopper,Daniel D. Buchanan,Noralane M. Lindor,Loic Le Marchand,Steven Gallinger,Robert W. Haile,Polly A. Newcomb,Shu Chen Huang,Gad Rennert,Gad Rennert,Graham Casey,Stephen B. Gruber +20 more
TL;DR: A genome-wide association study (GWAS) meta-analysis of colorectal cancer in participants from a population-based case-control study in Israel and a consortium study from the Colon Cancer Family Registry confirmed that 14 of 29 previously identified susceptibility variants were significantly associated with risk of colors in this study.