Thomas A. Jones

TL;DR: The results of an international collaboration to produce and make freely available a draft sequence of the human genome are reported and an initial analysis is presented, describing some of the insights that can be gleaned from the sequence.

TL;DR: The results of an international collaboration to produce a high-quality draft sequence of the mouse genome are reported and an initial comparative analysis of the Mouse and human genomes is presented, describing some of the insights that can be gleaned from the two sequences.

TL;DR: The upgrade of the authors' search pipeline to use Infernal 1.1 is described and improved homology detection ability is demonstrated by comparison with the previous version, and the new pipeline is easier for users to apply to their own data sets, and its ability to annotate RNAs in genomic and metagenomic data sets of various sizes is illustrated.

TL;DR: Recent advances in Dfam are described, most notably expansion to 4150 total families including a comprehensive set of known repeat families from four new organisms (mouse, zebrafish, fly and nematode).

TL;DR: A computational comparative genomic screen for ncRNA genes is described, to distinguish conserved RNA secondary structures from a background of other conserved sequences using probabilistic models of expected mutational patterns in pairwise sequence alignments.