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Yoshitaka Fujii
Researcher at Nagoya City University
Publications - 306
Citations - 22300
Yoshitaka Fujii is an academic researcher from Nagoya City University. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 59, co-authored 304 publications receiving 21040 citations.
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Journal ArticleDOI
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.
J. Guillermo Paez,Pasi A. Jänne,Pasi A. Jänne,Jeffrey C. Lee,Sean Tracy,Heidi Greulich,Heidi Greulich,Stacey Gabriel,Paula Herman,Frederic J. Kaye,Neal I. Lindeman,Titus J. Boggon,Katsuhiko Naoki,Hidefumini Sasaki,Yoshitaka Fujii,Michael J. Eck,William R. Sellers,William R. Sellers,William R. Sellers,Bruce E. Johnson,Bruce E. Johnson,Matthew Meyerson,Matthew Meyerson +22 more
TL;DR: Results suggest that EGFR mutations may predict sensitivity to gefitinib, and treatment with the EGFR kinase inhibitor gefitsinib causes tumor regression in some patients with NSCLC, more frequently in Japan.
Journal ArticleDOI
Characterizing the cancer genome in lung adenocarcinoma
Barbara A. Weir,Barbara A. Weir,Michele S. Woo,Gad Getz,Sven Perner,Sven Perner,Li Ding,Rameen Beroukhim,Rameen Beroukhim,William M. Lin,William M. Lin,Michael A. Province,Aldi T. Kraja,Laura A. Johnson,Kinjal Shah,Kinjal Shah,Mitsuo Sato,Roman K. Thomas,Justine A. Barletta,Ingrid B. Borecki,Stephen R. Broderick,Andrew C. Chang,Derek Y. Chiang,Derek Y. Chiang,Lucian R. Chirieac,Jeonghee Cho,Yoshitaka Fujii,Adi F. Gazdar,Thomas J. Giordano,Heidi Greulich,Heidi Greulich,Megan Hanna,Megan Hanna,Bruce E. Johnson,Mark G. Kris,Alex E. Lash,Ling Lin,Neal I. Lindeman,Elaine R. Mardis,John Douglas Mcpherson,John D. Minna,Margaret Morgan,Mark Nadel,Mark Nadel,Mark B. Orringer,John R. Osborne,Brad Ozenberger,Alex H. Ramos,Alex H. Ramos,James T. Robinson,Jack A. Roth,Valerie W. Rusch,Hidefumi Sasaki,Frances A. Shepherd,Carrie Sougnez,Margaret R. Spitz,Ming-Sound Tsao,David Twomey,Roel G.W. Verhaak,George M. Weinstock,David A. Wheeler,Wendy Winckler,Wendy Winckler,Akihiko Yoshizawa,Soyoung Yu,Maureen F. Zakowski,Qunyuan Zhang,David G. Beer,Ignacio I. Wistuba,Mark A. Watson,Levi A. Garraway,Levi A. Garraway,Marc Ladanyi,William D. Travis,William Pao,Mark A. Rubin,Mark A. Rubin,Stacey Gabriel,Richard A. Gibbs,Harold E. Varmus,Richard K. Wilson,Eric S. Lander,Eric S. Lander,Eric S. Lander,Matthew Meyerson,Matthew Meyerson +85 more
TL;DR: A large-scale project to characterize copy-number alterations in primary lung adenocarcinomas using dense single nucleotide polymorphism arrays identifies NKX2-1 (NK2 homeobox 1, also called TITF1), which lies in the minimal 14q13.3 amplification interval and encodes a lineage-specific transcription factor, as a novel candidate proto-oncogene involved in a significant fraction of lung carcinomas.
Journal ArticleDOI
Expression of survivin in esophageal cancer: correlation with the prognosis and response to chemotherapy.
Joji Kato,Yoshiyuki Kuwabara,Masami Mitani,Noriyuki Shinoda,Atsushi Sato,Tatsuya Toyama,Akira Mitsui,Tadashi Nishiwaki,Satoru Moriyama,Junzo Kudo,Yoshitaka Fujii +10 more
TL;DR: The results suggest that survivin expression may provide prognostic information in patients with esophageal cancer.
Journal ArticleDOI
Extended thymectomy for myasthenia gravis patients: a 20-year review.
Akira Masaoka,Yosuke Yamakawa,Hiroshi Niwa,Ichiro Fukai,Satoshi Kondo,Masayoshi Kobayashi,Yoshitaka Fujii,Yasumasa Monden +7 more
TL;DR: Extended thymectomy is an excellent operative procedure for myasthenia gravis in both nonthymomatous and thymomatomatous patients and was effective also in patients with ocular myasthecia gravis.
Journal ArticleDOI
Involvement of Histone H1.2 in Apoptosis Induced by DNA Double-Strand Breaks
Akimitsu Konishi,Akimitsu Konishi,Shigeomi Shimizu,Junko Hirota,Toshifumi Takao,Yuhong Fan,Yosuke Matsuoka,Lilin Zhang,Yoshihiro Yoneda,Yoshitaka Fujii,Arthur I. Skoultchi,Yoshihide Tsujimoto +11 more
TL;DR: The results indicate that histone H1.2 plays an important role in transmitting apoptotic signals from the nucleus to the mitochondria following DNA double-strand breaks, as well as that induced by TNF-alpha and UV irradiation.