Institution
Gdańsk Medical University
Education•Gdańsk, Poland•
About: Gdańsk Medical University is a education organization based out in Gdańsk, Poland. It is known for research contribution in the topics: Population & Cancer. The organization has 4893 authors who have published 11216 publications receiving 260523 citations.
Topics: Population, Cancer, Medicine, Blood pressure, Transplantation
Papers published on a yearly basis
Papers
More filters
••
University of Florence1, University of Ferrara2, University of Barcelona3, Gdańsk Medical University4, University College Dublin5, Royal Hampshire County Hospital6, Medical University of Graz7, St Bartholomew's Hospital8, Radboud University Nijmegen9, University of Stirling10, Nottingham City Hospital11, University of Milan12, University of Copenhagen13, Katholieke Universiteit Leuven14, University of Turin15, European Institute of Oncology16, Institute of Oncology Ljubljana17, National Health Service18, University of Crete19, Guy's and St Thomas' NHS Foundation Trust20
TL;DR: The standards of training in breast cancer are identified to harmonise and foster breast care training in Europe and contribute to the increase in the level of care in a breast unit as the input of qualified health professionals increases the quality of breast cancer patient care.
98 citations
••
TL;DR: ADT is presented here as a new, reliable and quantitative method of assessing burn wound depth on the basis of discrimination of the thermal properties of burnt tissue, and the best results coming from ADT.
98 citations
••
TL;DR: Human adipose-derived stem cells (ADSCs) are evaluated as a source of cells for heart valve tissue engineering investigating their ability to synthesize and process collagen and elastin and have important implications for the use of these cells in tissue engineering.
98 citations
••
TL;DR: Glycosaminoglycan-rich biological fluids inhibit the antibacterial effects of human cathelicidin LL-37 and polycations that bind to glycosaminglycans increase the antib bacterial activities of endogenous antimicrobial peptides in glycosamine-containing biological fluids.
Abstract: Objectives: The antibacterial activity of antimicrobial peptides is influenced by various factors such as salt content, pH and the presence of proteins. In this study, we explored the antibacterial action of the human cathelicidin LL-37 in physiologically relevant conditions, i.e. various human wound fluids, human plasma fractions and serum. Methods: Radial diffusion assays using Staphylococcus aureus and Escherichia coli were employed for the study of antibacterial effects of LL-37 in the presence of 12 different wound fluids, citrate-, heparin- or EDTA-plasma, or human serum. Glycosaminoglycan content of wound fluids was determined by an Alcian Blue-binding assay. Protein content of wound fluids was measured by the Bradford method. A slot-binding assay was used to study the effects of inhibitors on the interaction between LL-37 and glycosaminoglycans. Results: Five of twelve wound fluids derived from acute wounds showed marked inhibitory effects on the antibacterial action of LL-37. The inhibition was significantly correlated with high glycosaminoglycan content in wound fluid. Analogous to these findings, heparin-plasma strongly inhibited the antibacterial effect of LL-37. The interaction between LL-37 and glycosaminoglycans was abrogated by the cationic polymers DEAE-dextran and chitosan, yielding increased activity of LL-37. Conclusions: Glycosaminoglycan-rich biological fluids inhibit the antibacterial effects of LL-37. Furthermore, polycations that bind to glycosaminoglycans increase the antibacterial activities of endogenous antimicrobial peptides in glycosaminoglycan-containing biological fluids.
98 citations
••
TL;DR: The results showed that the production of IL2 is not disregulated in the 'healthy' people until the age of 60-70, and people not fulfilling all SP criteria are characterised by a lower level ofIL2 in the sera.
97 citations
Authors
Showing all 4927 results
Name | H-index | Papers | Citations |
---|---|---|---|
Magdi H. Yacoub | 109 | 1267 | 52431 |
Virend K. Somers | 106 | 615 | 54203 |
Felix Mitelman | 95 | 578 | 35416 |
Andrzej Slominski | 91 | 469 | 27900 |
Nils Mandahl | 86 | 427 | 25006 |
Fredrik Mertens | 84 | 406 | 28705 |
Enriqueta Felip | 83 | 622 | 53364 |
Pieter E. Postmus | 81 | 384 | 24039 |
Wilhelm Kriz | 73 | 222 | 19335 |
Godefridus J. Peters | 73 | 523 | 28315 |
Jacek Jassem | 73 | 602 | 35976 |
Piotr Rutkowski | 72 | 563 | 42218 |
Thomas Frodl | 70 | 258 | 16469 |
Eric J. Velazquez | 70 | 396 | 27539 |
Argye E. Hillis | 68 | 398 | 22230 |