Imperial Chemical Industries

About: Imperial Chemical Industries is a based out in . It is known for research contribution in the topics: Alkyl & Catalysis. The organization has 8189 authors who have published 7809 publications receiving 190252 citations. The organization is also known as: Imperial Chemical Industries Ltd.

Perspectives in adrenergic beta‐receptor blockade

Abstract: The adrenergic ß‐receptor blocking drugs currently undergoing clinical evaluation are classified in relation to their pharmacological properties. Particular consideration is given to those pharmacological properties that may be of importance in the clinical application of these drugs. The present evidence on the role in the ß‐blocking action of propranolol in angina pectoris and arrhythmias is reviewed, and it is concluded that this property is of major significance in these indications. Finally, recent advances in this field are summarized and possible future areas for research described.

A Bayesian Approach to Short-term Forecasting

Abstract: A new approach to short-term forecasting is described, based on Bayesian principles. The performance of conventional systems is often upset by the occurrence of changes in trend and slope, or transients. In this approach events of this nature are modelled explicitly, and successive data points are used to calculate the posterior probabilities of such events at each instant of time. The system produces not only single-figure forecasts but distributions of trend and slope values which are relevant to subsequent decisions based on forecasts.

Macro-lattice from segregated amorphous phases of a three block copolymer.

Abstract: THERMOPLASTIC elastomers represent a new and important family of polymeric materials. One of the most representative examples contains three blocks, styrene/butadiene/styrene (SBS), within a chain. At ambient temperatures the two chemical species separate. The B phase is rubbery, and provides the matrix for the highly dispersed S phase which is glassy. Owing to the molecular connexion between the two, the S phase acts like a cross-link and thus creates a network. At high enough temperatures this cross-linking effect due to the S phase is removed and the object becomes mouldable.

Factorial Designs, the |X′X| Criterion, and Some Related Matters

Abstract: Two of the basic approaches to choosing an n-point experimental design in many industrial situations are (i) to set down a simple factorial or fractional factorial design in the factors being studied, or (ii) to choose a design based on the well-known |X′X| criterion. Experimenters often prefer (i) due to its simplicity; our viewpoint here is that (ii) is much better. We first indicate some situations for which (when all the factors are restricted to a cuboidal region) the factorial approach is optimal, as judged by the |X′X| criterion, but the assumed models are often not sensible ones in practical work. We then examine what (similarly restricted) designs are optimal under the |X′X| criterion for the standard linear models of first and second order; because of the very rapid increase in computational difficulties, we consider only “cube plus star” type designs for k ≥ 3 (except for k = 3, n = 10). In spite of computational requirements, we recommend use of the |X′X| criterion in general rather than the i...