Institution
National University of La Plata
Education•La Plata, Argentina•
About: National University of La Plata is a education organization based out in La Plata, Argentina. It is known for research contribution in the topics: Population & Stars. The organization has 12993 authors who have published 30013 publications receiving 495118 citations. The organization is also known as: UNLP & Universidad Nacional de La Plata.
Papers published on a yearly basis
Papers
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TL;DR: The signal peptide of the arenavirus GP-C may serve additional functions in envelope glycoprotein structure and trafficking and is demonstrated to be myristoylated at its N-terminal glycine.
Abstract: Arenaviruses comprise a diverse family of rodent-borne viruses that are responsible for recurring and emerging outbreaks of viral hemorrhagic fevers worldwide. The Junin virus, a member of the New World arenaviruses, is endemic to the pampas grasslands of Argentina and is the etiologic agent of Argentine hemorrhagic fever. In this study, we have analyzed the assembly and function of the Junin virus envelope glycoproteins. The mature envelope glycoprotein complex is proteolytically processed from the GP-C precursor polypeptide and consists of three noncovalently associated subunits, G1, G2, and a stable 58-amino-acid signal peptide. This tripartite organization is found both on virions of the attenuated Candid 1 strain and in cells expressing the pathogenic MC2 strain GP-C gene. Replacement of the Junin virus GP-C signal peptide with that of human CD4 has little effect on glycoprotein assembly while abolishing the ability of the G1-G2 complex to mediate pH-dependent cell-cell fusion. In addition, we demonstrate that the Junin virus GP-C signal peptide subunit is myristoylated at its N-terminal glycine. Alanine substitution for the modified glycine residue in the GP-C signal peptide does not affect formation of the tripartite envelope glycoprotein complex but markedly reduces its membrane fusion activity. In contrast to the classical view that signal peptides act primarily in targeting nascent polypeptides to the endoplasmic reticulum, we suggest that the signal peptide of the arenavirus GP-C may serve additional functions in envelope glycoprotein structure and trafficking.
150 citations
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TL;DR: The aim of the present work is to review the state of the art of responsible mechanisms for organic solvent tolerance in Gram-positive bacteria, and their industrial and environmental biotechnology potential.
150 citations
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TL;DR: An overview will be presented on the negative-strand RNA plant viruses classified within the families Bunyaviridae, Rhabdoviraceae, Ophioviridae and floating genera Tenuivirus and Varicosavirus and genetic differences with the animal/human infecting counterparts and their evolutionary descendants will be described.
149 citations
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TL;DR: In this paper, the structural, electronic, and magnetic properties of doped rutile were studied for two different impurity concentrations (25% and 6.25%) considering different distributions of the impurities in the host lattice.
Abstract: In recent years there has been an intense search for room temperature ferromagnetism in semiconductors doped with dilute magnetic impurities, in particular, oxides. In this work we study the structural, electronic, and magnetic properties of doped rutile $\mathrm{Ti}{\mathrm{O}}_{2}$ for two different impurity concentrations (25% and 6.25%), considering different distributions of the impurities in the host lattice. Calculations were performed with ab initio methods, assuming that the magnetic impurities substitutionally replace the Ti ions. Our results show that a local magnetic moment appears in the cases of Mn, Fe, and Co impurities, but not in the cases of Ni and Cu impurities. They also show that in the system ${\mathrm{Ti}}_{1\ensuremath{-}x}{\mathrm{Co}}_{x}{\mathrm{O}}_{2}$ the magnetic ions align ferromagnetically, while in ${\mathrm{Ti}}_{1\ensuremath{-}x}{\mathrm{Mn}}_{x}{\mathrm{O}}_{2}$ and ${\mathrm{Ti}}_{1\ensuremath{-}x}{\mathrm{Fe}}_{x}{\mathrm{O}}_{2}$ the antiferromagnetic alignment is energetically favorable. We have also studied the effect of oxygen vacancies, which turned out to be very important. Their presence decreases the energy required to introduce the impurities in the host lattice and reciprocally, the presence of impurities is related to a higher vacancy concentration. The pairs impurity-nearest-neighbor oxygen vacancy seem to be the energetically preferred structures and to produce the highest local magnetic moments. Ni and even Cu impurities acquire magnetic moments in this environment.
149 citations
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TL;DR: In this article, a series of nanosized N-containing TiO2-based materials with Anatase-type structure and synthesized by a microemulsion method were tested in the photocatalytic degradation of methylcyclohexene, a representative example of volatile organic compound (VOC) present in urban atmospheres.
Abstract: A series of nanosized N-containing TiO2-based materials with Anatase-type structure and synthesized by a microemulsion method were tested in the photocatalytic degradation of methylcyclohexene, a representative example of volatile organic compound (VOC) present in urban atmospheres. A combined diffuse reflectance infrared (DRIFTS) and X-ray absorption (XAS) spectroscopic study allows to analyze the nature and number of N-containing species and other defects (particularly oxygen vacancies) present in the solid catalysts. The structural characterization was used to interpret the UV–vis spectra of the solids and the resulting joint information allows to rationalize the photocatalytic activity differences observed through the samples under sunlight-type excitation. We founded that our samples contain substitutional and interstitial N-containing impurities and a significant number of oxygen vacancies. Photocatalytic activity is correlated with an optimum of oxygen vacancies, above and below which a decrease of the steady state reaction rate is observed. The physico-chemical bases of this behavior are discussed on the light of the above mentioned experimental results.
149 citations
Authors
Showing all 13198 results
Name | H-index | Papers | Citations |
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David Cameron | 154 | 1586 | 126067 |
Subir Sarkar | 149 | 1542 | 144614 |
Mayda Velasco | 137 | 1309 | 87579 |
Diego F. Torres | 137 | 948 | 72180 |
Heidi Sandaker | 128 | 999 | 76517 |
Vincent Garonne | 128 | 921 | 76980 |
Farid Ould-Saada | 128 | 931 | 76394 |
Ole Røhne | 128 | 1038 | 75752 |
Peter Hansen | 128 | 1271 | 86210 |
Maria-Teresa Dova | 127 | 778 | 73558 |
Vladimir Sulin | 127 | 884 | 75329 |
Andrei Snesarev | 127 | 875 | 74907 |
James Catmore | 127 | 892 | 75086 |
Ruslan Mashinistov | 126 | 860 | 73897 |
Fernando Monticelli | 126 | 843 | 73385 |