Institution
National University of La Plata
Education•La Plata, Argentina•
About: National University of La Plata is a education organization based out in La Plata, Argentina. It is known for research contribution in the topics: Population & Stars. The organization has 12993 authors who have published 30013 publications receiving 495118 citations. The organization is also known as: UNLP & Universidad Nacional de La Plata.
Papers published on a yearly basis
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TL;DR: In this article, the jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector using proton-proton collision data with a centre-of-mass energy of [Formula: see text]TeV corresponding to an integrated luminosity of [formula] see text][formula:see text].
Abstract: The jet energy scale (JES) and its systematic uncertainty are determined for jets measured with the ATLAS detector using proton-proton collision data with a centre-of-mass energy of [Formula: see text] TeV corresponding to an integrated luminosity of [Formula: see text][Formula: see text]. Jets are reconstructed from energy deposits forming topological clusters of calorimeter cells using the anti-[Formula: see text] algorithm with distance parameters [Formula: see text] or [Formula: see text], and are calibrated using MC simulations. A residual JES correction is applied to account for differences between data and MC simulations. This correction and its systematic uncertainty are estimated using a combination of in situ techniques exploiting the transverse momentum balance between a jet and a reference object such as a photon or a [Formula: see text] boson, for [Formula: see text] and pseudorapidities [Formula: see text]. The effect of multiple proton-proton interactions is corrected for, and an uncertainty is evaluated using in situ techniques. The smallest JES uncertainty of less than 1 % is found in the central calorimeter region ([Formula: see text]) for jets with [Formula: see text]. For central jets at lower [Formula: see text], the uncertainty is about 3 %. A consistent JES estimate is found using measurements of the calorimeter response of single hadrons in proton-proton collisions and test-beam data, which also provide the estimate for [Formula: see text] TeV. The calibration of forward jets is derived from dijet [Formula: see text] balance measurements. The resulting uncertainty reaches its largest value of 6 % for low-[Formula: see text] jets at [Formula: see text]. Additional JES uncertainties due to specific event topologies, such as close-by jets or selections of event samples with an enhanced content of jets originating from light quarks or gluons, are also discussed. The magnitude of these uncertainties depends on the event sample used in a given physics analysis, but typically amounts to 0.5-3 %.
294 citations
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TL;DR: It is suggested that bindarit or Clod-Lip abrogates protumoral-associated macrophages in human melanoma xenografts and could be considered as complementary approaches to antiangiogenic therapy.
294 citations
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Federal University of Rio de Janeiro1, Simon Fraser University2, National University of La Plata3, Oswaldo Cruz Foundation4, Washington University in St. Louis5, University of the Republic6, European Bioinformatics Institute7, National Institutes of Health8, Federal University of Uberlandia9, Universidade Federal de Minas Gerais10, Sao Paulo State University11, State University of Norte Fluminense12, Johns Hopkins University13, University of Notre Dame14, Universidade Federal Rural do Rio de Janeiro15, Pompeu Fabra University16, Centre national de la recherche scientifique17, University of Toronto18, Centers for Disease Control and Prevention19, Instituto Politécnico Nacional20, Florida International University21, Universidade Federal do Espírito Santo22, University of Illinois at Urbana–Champaign23, University of Santiago de Compostela24, Virginia Tech25, University of Cambridge26, University of Manitoba27
TL;DR: The first genome sequence of a nondipteran insect vector of an important human parasitic disease is described, which provides critical information on the physiology and evolution of this important vector species and should be instrumental for the development of innovative disease control methods.
Abstract: Rhodnius prolixus not only has served as a model organism for the study of insect physiology, but also is a major vector of Chagas disease, an illness that affects approximately seven million people worldwide. We sequenced the genome of R. prolixus, generated assembled sequences covering 95% of the genome (∼ 702 Mb), including 15,456 putative protein-coding genes, and completed comprehensive genomic analyses of this obligate blood-feeding insect. Although immune-deficiency (IMD)-mediated immune responses were observed, R. prolixus putatively lacks key components of the IMD pathway, suggesting a reorganization of the canonical immune signaling network. Although both Toll and IMD effectors controlled intestinal microbiota, neither affected Trypanosoma cruzi, the causal agent of Chagas disease, implying the existence of evasion or tolerance mechanisms. R. prolixus has experienced an extensive loss of selenoprotein genes, with its repertoire reduced to only two proteins, one of which is a selenocysteine-based glutathione peroxidase, the first found in insects. The genome contained actively transcribed, horizontally transferred genes from Wolbachia sp., which showed evidence of codon use evolution toward the insect use pattern. Comparative protein analyses revealed many lineage-specific expansions and putative gene absences in R. prolixus, including tandem expansions of genes related to chemoreception, feeding, and digestion that possibly contributed to the evolution of a blood-feeding lifestyle. The genome assembly and these associated analyses provide critical information on the physiology and evolution of this important vector species and should be instrumental for the development of innovative disease control methods.
293 citations
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TL;DR: The first randomised trial of community-led total sanitation (CLTS) to assess its effect on child health in Koulikoro, Mali was conducted in 2011 as discussed by the authors.
291 citations
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TL;DR: The change in the properties of the styrene-butadiene block copolymers (SBS) modified asphalt under different ageing conditions has been studied in this paper, where normalized test and rotational viscosities show the effect of the degradation and the modification of the polymer-asphalt interactions with the severity of the ageing.
289 citations
Authors
Showing all 13198 results
Name | H-index | Papers | Citations |
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David Cameron | 154 | 1586 | 126067 |
Subir Sarkar | 149 | 1542 | 144614 |
Mayda Velasco | 137 | 1309 | 87579 |
Diego F. Torres | 137 | 948 | 72180 |
Heidi Sandaker | 128 | 999 | 76517 |
Vincent Garonne | 128 | 921 | 76980 |
Farid Ould-Saada | 128 | 931 | 76394 |
Ole Røhne | 128 | 1038 | 75752 |
Peter Hansen | 128 | 1271 | 86210 |
Maria-Teresa Dova | 127 | 778 | 73558 |
Vladimir Sulin | 127 | 884 | 75329 |
Andrei Snesarev | 127 | 875 | 74907 |
James Catmore | 127 | 892 | 75086 |
Ruslan Mashinistov | 126 | 860 | 73897 |
Fernando Monticelli | 126 | 843 | 73385 |