Institution
Northwest Community College
Education•Terrace, British Columbia, Canada•
About: Northwest Community College is a education organization based out in Terrace, British Columbia, Canada. It is known for research contribution in the topics: Government & Gene. The organization has 18 authors who have published 23 publications receiving 735 citations.
Topics: Government, Gene, Bessel function, Enhancer, Wave function
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University of Copenhagen1, University of California, Berkeley2, University of Massachusetts Amherst3, Wellcome Trust Sanger Institute4, Technical University of Denmark5, Pennsylvania State University6, La Trobe University7, Stanford University8, University of Cambridge9, King Abdullah University of Science and Technology10, University of Tartu11, Estonian Biocentre12, University of California, San Francisco13, Washington State University14, University of Porto15, University of Illinois at Urbana–Champaign16, Carlos III Health Institute17, University of Utah18, Science for Life Laboratory19, Aarhus University20, University College London21, University of Reading22, University of Bristol23, University of Guadalajara24, University of Bologna25, Oregon State University26, University of Paris27, University of Zurich28, Max Planck Society29, St. John's University30, University of California, Irvine31, University of Tarapacá32, University of Toulouse33, Novosibirsk State University34, Russian Academy of Sciences35, Kemerovo State University36, Bashkir State University37, North-Eastern Federal University38, Western Washington University39, Northwest Community College40, University of Western Ontario41, Simon Fraser University42, Laboratory of Molecular Biology43, University of Kansas44, University of California, Davis45, Texas A&M University46, Santa Barbara Museum of Natural History47, Southern Methodist University48
TL;DR: The results suggest that there has been gene flow between some Native Americans from both North and South America and groups related to East Asians and Australo-Melanesians, the latter possibly through an East Asian route that might have included ancestors of modern Aleutian Islanders.
Abstract: How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericues and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model.
459 citations
TL;DR: In this paper, the authors analyzed 408,493 SARS-CoV-2 genomes submitted to GISAID database with respect to genomic clades and their geographic, age, and gender distributions.
Abstract: Expansion of COVID-19 worldwide increases interest in unraveling genomic variations of novel SARS-CoV-2 virus. Metadata of 408,493 SARS-CoV-2 genomes submitted to GISAID database were analyzed with respect to genomic clades and their geographic, age, and gender distributions. Of the currently known SARS-CoV-2 clades, clade GR was the most prevalent worldwide followed by GV then GH. Chronological analysis revealed expansion in SARS-CoV-2 clades carrying D614G mutations with the predominance of the newest clade, GV, in the last three months. D614G clades prevail in countries with more COVID-19 cases. Of them, the clades GH and GR were more frequently recovered from severe or deceased COVID-19 cases. In contrast, G and GV clades showed a significantly higher prevalence among asymptomatic patients or those with mild disease. Metadata analysis showed higher (p < 0.05) prevalence of severe/deceased cases among males than females and predominance of GR clade in female patients. Furthermore, severe disease/death was more prevalent (p < 0.05) in elderly than in adults/children. Higher prevalence of the GV clade in children compared to other age groups was also evident. These findings uniquely provide a statistical evidence on the adaptation-driven evolution of SARS-CoV-2 leading to altered infectivity, virulence, and mortality.
73 citations
TL;DR: Four ancient and three living individuals of the northern Northwest Coast of North America, specifically the north coast of British Columbia, Canada, current home to the indigenous Tsimshian, Haida, and Nisga’a, generated complete mitochondrial genomes (mitogenomes) to gain a better understanding of North American population history.
Abstract: To gain a better understanding of North American population history, complete mitochondrial genomes (mitogenomes) were generated from four ancient and three living individuals of the northern Northwest Coast of North America, specifically the north coast of British Columbia, Canada, current home to the indigenous Tsimshian, Haida, and Nisga’a. The mitogenomes of all individuals were previously unknown and assigned to new sub-haplogroup designations D4h3a7, A2ag and A2ah. The analysis of mitogenomes allows for more detailed analyses of presumed ancestor–descendant relationships than sequencing only the HVSI region of the mitochondrial genome, a more traditional approach in local population studies. The results of this study provide contrasting examples of the evolution of Native American mitogenomes. Those belonging to sub-haplogroups A2ag and A2ah exhibit temporal continuity in this region for 5000 years up until the present day. Of possible associative significance is that archaeologically identified house structures in this region maintain similar characteristics for this same period of time, demonstrating cultural continuity in residence patterns. The individual dated to 6000 years before present (BP) exhibited a mitogenome belonging to sub-haplogroup D4h3a. This sub-haplogroup was earlier identified in the same general area at 10300 years BP on Prince of Wales Island, Alaska, and may have gone extinct, as it has not been observed in any living individuals of the Northwest Coast. The presented case studies demonstrate the different evolutionary paths of mitogenomes over time on the Northwest Coast.
60 citations
TL;DR: In this article, a study was designed to answer two questions: (1) Can cognitive strategies to increase testwiseness be taught? (2) Can the test-wise strategies be generalized by students so they can improve test-score.
Abstract: The study was designed to answer two questions: (1) Can cognitive strategies to increase testwiseness be taught? (2) Can the testwiseness strategies be generalized by students so they can improve t...
43 citations
TL;DR: In this article, the authors employ percussion coring to identify early Holocene shell midden components at two types of sites on the Northwest Coast of North America, and suggest that pre-5000 BP forms of these sites may be more common than previously thought.
42 citations
Authors
Showing all 18 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| John Krisinger | 13 | 13 | 512 |
| Ahmed S. Khairalla | 12 | 20 | 289 |
| Chelsey Geralda Armstrong | 10 | 21 | 460 |
| David Archer | 8 | 8 | 588 |
| Ralph Eric Turner | 6 | 9 | 92 |
| Courtney M. Bell | 5 | 6 | 180 |
| Aaron D. Peters | 5 | 5 | 231 |
| R. R. Hitchcock | 2 | 2 | 49 |
| Pouyan Mahboubi | 2 | 2 | 47 |
| Jacob Muller | 1 | 3 | 7 |
| Kuntebomanahalli Thimmaiah | 1 | 2 | 14 |
| David Heinimann | 1 | 2 | 2 |
| Becky Faure Dooley | 1 | 1 | 4 |
| Kathy S. Williams | 1 | 1 | 43 |
| Winifred S. Wasden | 1 | 1 | 1 |