Shandong Normal University

About: Shandong Normal University is a education organization based out in Jinan, Shandong, China. It is known for research contribution in the topics: Laser & Catalysis. The organization has 12378 authors who have published 12576 publications receiving 174572 citations.

Metformin activates AMPK/SIRT1/NF-κB pathway and induces mitochondrial dysfunction to drive caspase3/GSDME-mediated cancer cell pyroptosis.

Abstract: Pyroptosis is a form of programmed cell death initiated by inflammasomes and is critical for immunity. SIRT1, a NAD+-dependent deacetylase, plays multiple roles in inflammatory response and immunit...

A hybrid multi-objective artificial bee colony algorithm for flexible task scheduling problems in cloud computing system

Abstract: In this study, the flexible task scheduling problem in a cloud computing system is studied and solved by a hybrid discrete artificial bee colony (ABC) algorithm, where the considered problem is firstly modeled as a hybrid flowshop scheduling (HFS) problem. Both a single objective and multiple objectives are considered. In multiple objective HFS problems, three objectives, i.e., minimization of the maximum completion time, maximum device workload, and total workloads of all devices, are considered simultaneously. Two different kinds of HFS are considered, i.e., HFS with identical parallel machines and HFS with unrelated machines. In the proposed algorithm, three types of artificial bees are included as in the classical ABC algorithm, i.e., the employed bee, the onlooker bee, and the scout bee. Each solution is represented as an integer string. To consider the problem features, several different types of perturbation structures are investigated to enhance the searching abilities. An improved version of the adaptive perturbation structure is embedded in the proposed algorithm to balance the exploitation and exploration ability. A simple but efficient selection and updated approach are applied to enhance the exploitation process. To further improve the exploitation abilities, a deep-exploitation operator is designed. An improved scout bee employed with different local search methods for the best food source or the abandoned solution is designed and can increase the convergence ability of the proposed algorithm. The proposed algorithm is tested on sets of the well-known benchmark instances, and the performance of the proposed algorithm is verified.

Higher-order topological semimetal in acoustic crystals

Abstract: The notion of higher-order topological insulators has endowed materials with topological states beyond the first order. Particularly, a three-dimensional (3D) higher-order topological insulator can host topologically protected 1D hinge states, referred to as the second-order topological insulator, or 0D corner states, referred to as the third-order topological insulator. Similarly, a 3D higher-order topological semimetal can be envisaged if it hosts states on the 1D hinges. Here we report the realization of a second-order topological Weyl semimetal in a 3D-printed acoustic crystal, which possesses Weyl points in 3D momentum space, 2D Fermi arc states on surfaces and 1D gapless states on hinges. Like the arc surface states, the hinge states also connect the projections of the Weyl points. Our experimental results evidence the existence of the higher-order topological semimetal, which may pave the way towards innovative acoustic devices. A second-order topological Weyl semimetal based on a 3D-printed acoustic crystal, exhibiting Weyl points, Fermi arc surface states, and hinge states, has been experimentally demonstrated.