South China University of Technology

About: South China University of Technology is a education organization based out in Guangzhou, China. It is known for research contribution in the topics: Catalysis & Adsorption. The organization has 62343 authors who have published 69468 publications receiving 1251592 citations. The organization is also known as: SCUT & Huánán Lǐgōng Dàxué.

Solution-processed bulk heterojunction solar cells based on a porphyrin small molecule with 7% power conversion efficiency

Abstract: A porphyrin small molecule with less bulky substituents at the porphyrin periphery has been synthesized as a donor material, which exhibits a power conversion efficiency of up to 723% under AM 15 G irradiation (100 mW cm−2) for the solution-processed bulk heterojunction solar cells with PC61BM as the acceptor material

Synthesis of g-C3N4 by different precursors under burning explosion effect and its photocatalytic degradation for tylosin

Abstract: The use of abundant sunlight for semiconductor photo-degradation of antibiotics is an ideal way to solve global water pollution. Here, the sodium nitrate modified photocatalysts exhibits enhanced photocatalytic efficiency for degradation of tylosin under simulated sunlight irradiation over g-C3N4 alone. In addition, the pure g-C3N4 and sodium nitrate modified g-C3N4 photocatalysts were investigated in terms of their crystal structures, morphologies, optical properties by using XRD, SEM, TEM, Raman, FTIR, UV–vis and XPS. On the basis of these results, the morphology dependence of the visible light absorption and the photocatalytic efficiency under simulated sunlight irradiation has been systematically investigated. It was found that the type of precursors and the molar ratio of sodium nitrate have an evident impact on the crystal structure of g-C3N4, and photocatalytic performance due to varied reaction pathways and degree of condensation. The photocatalytic activity evaluated under simulated sunlight indicates that the as-synthesized photocatalysts is effective in obtaining the energy of solar spectrum and transforming it into the chemical energy for tylosin degradation.

Flexible and Ultrathin Waterproof Cellular Membranes Based on High-Conjunction Metal-Wrapped Polymer Nanofibers for Electromagnetic Interference Shielding.

Abstract: Ultrathin, lightweight, and flexible electromagnetic interference (EMI) shielding materials are urgently demanded to address EM radiation pollution. Efficient design to utilize the shields' microstructures is crucial yet remains highly challenging for maximum EMI shielding effectiveness (SE) while minimizing material consumption. Herein, novel cellular membranes are designed based on a facile polydopamine-assisted metal (copper or silver) deposition on electrospun polymer nanofibers. The membranes can efficiently exploit the high-conjunction cellular structures of metal and polymer nanofibers, and their interactions for excellent electrical conductivity, mechanical flexibility, and ultrahigh EMI shielding performance. EMI SE reaches more than 53 dB in an ultra-broadband frequency range at a membrane thickness of merely 2.5 µm and a density of 1.6 g cm-3 , and an SE of 44.7 dB is accomplished at the lowest thickness of 1.2 µm. The normalized specific SE is up to 232 860 dB cm2 g-1 , significantly surpassing that of other shielding materials ever reported. More, integrated functionalities are discovered in the membrane, such as antibacterial, waterproof properties, excellent air permeability, high resistance to mechanical deformations and low-voltage uniform heating performance, offering strong potential for applications in aerospace and portable and wearable smart electronics.

YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation.

Abstract: N6-methyladenosine (m6A) RNA methylation contributes to the cancer stem cell (CSC) phenotype through regulating gene expression. YTHDF2, an m6A reader, was shown to be associated with hepatocellular carcinoma (HCC) patient prognosis. However, the effect of YTHDF2 on liver CSC and cancer metastasis and the molecular mechanism of this effect have not been documented. Here, we show that YTHDF2 expression is negatively correlated with HCC patient survival in both data from the Cancer Genome Atlas (TCGA) database and clinical data from our center. By detecting CD133+ cells and carrying out sphere culture assays, we found that knockdown of YTHDF2 led to impaired stemness in Hep3B and Huh7 cells. In contrast, overexpression of YTHDF2 increased the CSC phenotype. Mechanistically, the knockdown and overexpression of YTHDF2 in liver cancer cells resulted in decreased and increased m6A levels in the 5'-untranslated region (UTR) of OCT4 mRNA, respectively, leading to decreased and increased OCT4 protein expression, respectively. A luciferase activity assay showed that mutation of the corresponding m6A methylation sequence in the 5'-UTR of OCT4 mRNA caused significantly decreased gene expression, suggesting a role for YTHDF2-dependent m6A methylation in protein translation. Polysome profiling results also indicated the knockdown and overexpression of YTHDF2 could decrease and increase OCT4 translation, respectively. In particular, overexpression of OCT4 rescued the impaired stemness caused by YTHDF2 depletion, which confirmed the effect of YTHDF2 on CSC phenotype is dependent on OCT4. In vivo, the loss of YTHDF2 reduced tumor burden and inhibited lung metastasis following orthotopic transplantation in nude mice. Last, we demonstrated that YTHDF2 expression is positively correlated with OCT4 expression and m6A levels in the 5'-UTR of OCT4 mRNA in clinical HCC specimens. In conclusion, YTHDF2 promotes the CSC liver phenotype and cancer metastasis by modulating the m6A methylation of OCT4 mRNA.