Tunis University

About: Tunis University is a education organization based out in Tunis, Tunisia. It is known for research contribution in the topics: Population & Thin film. The organization has 11745 authors who have published 15400 publications receiving 154900 citations. The organization is also known as: University of Tunis & UT.

The Tunisian Revolution: The Revolution of Dignity

Abstract: This article not only recounts the events that led to the revolution in Tunisia, but also provides an analysis of its causes, describes its significant actors, and attempts to put the Tunisian uprising in comparative perspective with the other revolutions in North Africa that followed it. To explain the revolt, the article focuses on the disparities in wealth distribution between interior and coastal Tunisia; the bleak employment prospects of Tunisian youth; fatigue with President Zine El Abidine Ben Ali's system of authoritarianism; the use of e-mail, text messaging, and Facebook to broadcast the revolution; and the special roles played by lawyers, judges, and labor union activists in organizing the later stages of the revolution. Additional analyses are provided concerning the disparate roles played by the army and the police in supporting and opposing the revolution.

Paleogeographic and geodynamic Miocene evolution of the Tunisian Tell (Numidian and Post-Numidian Successions): bearing with the Maghrebian Chain

Abstract: The Numidian and Post-Numidian stratigraphy of the Tunisian Tell has been updated based on 16 stratigraphic sections belonging to the Massylian sub-domain of the Maghrebian Flysch Basin and to the External Domain. The new data concern detailed litho- and biostratigraphy, gaps, synchronous marker levels, lateral correlations, tectonic contacts, etc. The successions studied show many diachronous and unconformity boundaries delimiting sedimentary depositional sequences related to some tectonic/sedimentary processes. Two main Miocene sedimentary successions (Numidian and Post-Numidian) are recognized overlying the Sub-Numidian Succession (pre-Early Aquitanian) by new integrated (planktonic foraminifera and calcareous nannoplankton) chronostratigraphic analyses, allowing an update of the formations studied. The Miocene tectonic/sedimentary relationships and the timing of the deformation are summarized as follows: (1) the activation of a foredeep stage and a tectogenesis phase gives rise to an accretionary orogenic wedge during mainly the Early Miocene; (2) a late-orogenic phase is checked in the Late Burdigalian-Early Langhian characterized by a marine glauconitic terrigenous sedimentation; (3) a post-orogenic generalized phase is confirmed from the Middle Miocene on in shallow marine or continental sedimentation. These results show good correlation along the Maghrebian Chain and Betic Cordillera. Finally, a paleogeographic and geodynamic evolutionary model concerning the Miocene African Tunisian Margin is postulated.

The effect of tobacco, XPC, ERCC2 and ERCC5 genetic variants in bladder cancer development

Abstract: In this work, we have conducted a case-control study in order to assess the effect of tobacco and three genetic polymorphisms in XPC, ERCC2 and ERCC5 genes (rs2228001, rs13181 and rs17655) in bladder cancer development in Tunisia. We have also tried to evaluate whether these variants affect the bladder tumor stage and grade. The patients group was constituted of 193 newly diagnosed cases of bladder tumors. The controls group was constituted of non-related healthy subjects. The rs2228001, rs13181 and rs17655 polymorphisms were genotyped using a polymerase chain reaction-restriction fragment length polymorphism technique. Our data have reported that non smoker and light smoker patients (1-19PY) are protected against bladder cancer development. Moreover, light smokers have less risk for developing advanced tumors stage. When we investigated the effect of genetic polymorphisms in bladder cancer development we have found that ERCC2 and ERCC5 variants were not implicated in the bladder cancer occurrence. However, the mutated homozygous genotype for XPC gene was associated with 2.09-fold increased risk of developing bladder cancer compared to the control carrying the wild genotype (p = 0.03, OR = 2.09, CI 95% 1.09-3.99). Finally, we have found that the XPC, ERCC2 and ERCC5 variants don't affect the tumors stage and grade. These results suggest that the mutated homozygous genotype for XPC gene was associated with increased risk of developing bladder. However we have found no association between rs2228001, rs13181 and rs17655 polymorphisms and tumors stage and grade.