Tunis University

About: Tunis University is a education organization based out in Tunis, Tunisia. It is known for research contribution in the topics: Population & Thin film. The organization has 11745 authors who have published 15400 publications receiving 154900 citations. The organization is also known as: University of Tunis & UT.

Inhibition of protein misfolding and aggregation by natural phenolic compounds

Abstract: Protein misfolding and aggregation into fibrillar deposits is a common feature of a large group of degenerative diseases affecting the central nervous system or peripheral organs, termed protein misfolding disorders (PMDs). Despite their established toxic nature, clinical trials aiming to reduce misfolded aggregates have been unsuccessful in treating or curing PMDs. An interesting possibility for disease intervention is the regular intake of natural food or herbal extracts, which contain active molecules that inhibit aggregation or induce the disassembly of misfolded aggregates. Among natural compounds, phenolic molecules are of particular interest, since most have dual activity as amyloid aggregation inhibitors and antioxidants. In this article, we review many phenolic natural compounds which have been reported in diverse model systems to have the potential to delay or prevent the development of various PMDs, including Alzheimer's and Parkinson's diseases, prion diseases, amyotrophic lateral sclerosis, systemic amyloidosis, and type 2 diabetes. The lower toxicity of natural compounds compared to synthetic chemical molecules suggest that they could serve as a good starting point to discover protein misfolding inhibitors that might be useful for the treatment of various incurable diseases.

Kinetic and thermodynamic studies of hydrogen storage alloys as negative electrode materials for Ni/MH batteries: a review

Abstract: This paper reviews the present performances of intermetallic compound families as materials for negative electrodes of rechargeable Ni/MH batteries The performance of the metal-hydride electrode is determined by both the kinetics of the processes occurring at the metal/solution interface and the rate of hydrogen diffusion within the bulk of the alloy Thermodynamic and electrochemical properties for each hydride compound family will be reported The steps of hydrogen absorption/desorption such as charge-transfer and hydrogen diffusion for evaluating the electrochemical properties of hydrogen storage alloys are discussed Exchange current density (I 0) and hydrogen diffusion coefficient (D H) are the two most important parameters for evaluating the electrochemical properties of metal hydride electrode The values of the two parameters for a number of hydrogen storage alloys are compared The relationship between alloy composition and electrochemical properties is noted and evaluated

Nonlinear coupled fixed point theorems in ordered generalized metric spaces with integral type

Abstract: In this article, we study coupled coincidence and coupled common fixed point theorems in ordered generalized metric spaces for nonlinear contraction condition related to a pair of altering distance functions. Our results generalize and modify several comparable results in the literature. 2000 MSC: 54H25; 47H10; 54E50.

Prevention and treatment of bile duct injuries during laparoscopic cholecystectomy: the clinical practice guidelines of the European Association for Endoscopic Surgery (EAES).

Abstract: Background Laparoscopic cholecystectomy is one of the most common surgical procedures in Europe (and the world) and has become the standard procedure for the management of symptomatic cholelithiasis or acute cholecystitis in patients without specific contraindications. Bile duct injuries (BDI) are rare but serious complications that can occur during a laparoscopic cholecystectomy. Prevention and management of BDI has given rise to a host of publications but very few recommendations, especially in Europe.

Oil prices and MENA stock markets: new evidence from nonlinear and asymmetric causalities during and after the crisis period

Abstract: This article investigates the potential of nonlinear causal relationships between world oil prices and stock markets in Middle East and North Africa (MENA) countries during a black swan period that is characterized by rarity and devastating impacts. Our study is carried out using the daily data for 11 MENA countries over the period from 2 July 2007 to 27 August 2012. By using the nonlinear and asymmetric causality test of Kyrtsou and Labys (2006), we mainly find that: (i) the oil prices and MENA stock markets interact in a nonlinear manner; (ii) the signs of changes in the causing variables are important for detecting the true causality links between the variables and (iii) the nonlinear causality is more pronounced in the case of the Brent than West Texas Intermediate oil prices.