Institution
University of Basel
Education•Basel, Basel-Stadt, Switzerland•
About: University of Basel is a education organization based out in Basel, Basel-Stadt, Switzerland. It is known for research contribution in the topics: Population & Gene. The organization has 25084 authors who have published 52975 publications receiving 2388002 citations. The organization is also known as: Universität Basel & Basel University.
Topics: Population, Gene, Medicine, Context (language use), Transplantation
Papers published on a yearly basis
Papers
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TL;DR: Calculation of stability constants from spectroscopic data is then as straightforward as from potentiometric titration curves and gives results of analogous reproducibility.
451 citations
TL;DR: A mechanism of action is proposed that delineates the dynamic role of the protein moiety of this enzyme based on crystallographically determined spatial structures of the mitochondrial isoenzyme in its unliganded forms and in complexes with substrate analogues, as well as on model building studies.
451 citations
TL;DR: In this article, the authors followed the trafficking route of newly made YFP-tagged Pex3 and Pex19 proteins by real-time fluorescence microscopy in Saccharomyces cerevisiae.
450 citations
TL;DR: Comparisons of the Antennapedia homeodomain with prokaryotic repressors showed that there are also significant differences in the molecular architectures, which support the view that the third helix of the homeodOMain may function as the DNA recognition site.
450 citations
TL;DR: The interplay of nucleosome packaging and chromatin access contributes to the regulation of transcription, replication and repair in eukaryotes is discussed by reviewing the current understanding.
Abstract: In eukaryotes, all DNA-templated reactions occur in the context of chromatin. Nucleosome packaging inherently restricts DNA accessibility for regulatory proteins but also provides an opportunity to regulate DNA-based processes through modulating nucleosome positions and local chromatin structure. Recent advances in genome-scale methods are yielding increasingly detailed profiles of the genomic distribution of nucleosomes, their modifications and their modifiers. The picture now emerging is one in which the dynamic control of genome accessibility is governed by contributions from DNA sequence, ATP-dependent chromatin remodelling and nucleosome modifications. Here we discuss the interplay of these processes by reviewing our current understanding of how chromatin access contributes to the regulation of transcription, replication and repair.
450 citations
Authors
Showing all 25374 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Yang Yang | 171 | 2644 | 153049 |
| Martin Karplus | 163 | 831 | 138492 |
| Frank J. Gonzalez | 160 | 1144 | 96971 |
| Paul Emery | 158 | 1314 | 121293 |
| Matthias Egger | 152 | 901 | 184176 |
| Don W. Cleveland | 152 | 444 | 84737 |
| Ashok Kumar | 151 | 5654 | 164086 |
| Kurt Wüthrich | 143 | 739 | 103253 |
| Thomas J. Smith | 140 | 1775 | 113919 |
| Robert Huber | 139 | 671 | 73557 |
| Peter Robmann | 135 | 1438 | 97569 |
| Ernst Detlef Schulze | 133 | 670 | 69504 |
| Michael Levine | 129 | 586 | 55963 |
| Claudio Santoni | 129 | 1027 | 80598 |
| Pablo Garcia-Abia | 126 | 989 | 78690 |