scispace - formally typeset
Search or ask a question
Institution

University of Manitoba

EducationWinnipeg, Manitoba, Canada
About: University of Manitoba is a education organization based out in Winnipeg, Manitoba, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 31888 authors who have published 66592 publications receiving 2095493 citations.


Papers
More filters
Journal Article
TL;DR: The Control Preferences Scale was developed to measure a construct that emerged from a grounded theory of how treatment decisions are made among people with life-threatening illnesses to be a clinically relevant, easily administered, valid, and reliable measure of preferred roles in health-care decision-making.
Abstract: The Control Preferences Scale (CPS) was developed to measure a construct that emerged from a grounded theory of how treatment decisions are made among people with life-threatening illnesses. The control preferences construct is defined as "the degree of control an individual wants to assume when decisions are being made about medical treatment." The CPS consists of five cards that each portrays a different role in treatment decision-making using a statement and a cartoon. These roles range from the individual making the treatment decisions, through the individual making the decisions jointly with the physician, to the physician making the decisions. The CPS involves subjects in making a series of paired comparisons to provide their total preference order over the five cards. These preference orders are analyzed using unfolding theory to determine the distribution of preferences in different populations and the effect of covariates on consumer preferences. The scale has been tested in a variety of populations, ranging from the general public to highly stressed groups. The CPS has proven to be a clinically relevant, easily administered, valid, and reliable measure of preferred roles in health-care decision-making.

796 citations

Journal ArticleDOI
TL;DR: In this article, the authors summarize more than 180 site years of eddy covariance measurements of carbon dioxide flux made at forest chronosequences in North America and show that carbon loss from all ecosystems following a stand-replacing disturbance, becoming a carbon sink by 20 years for all ecosystems and by 10 years for most.
Abstract: Disturbances are important for renewal of North American forests. Here we summarize more than 180 site years of eddy covariance measurements of carbon dioxide flux made at forest chronosequences in North America. The disturbances included stand-replacing fire (Alaska, Arizona, Manitoba, and Saskatchewan) and harvest (British Columbia, Florida, New Brunswick, Oregon, Quebec, Saskatchewan, and Wisconsin) events, insect infestations (gypsy moth, forest tent caterpillar, and mountain pine beetle), Hurricane Wilma, and silvicultural thinning (Arizona, California, and New Brunswick). Net ecosystem production (NEP) showed a carbon loss from all ecosystems following a stand-replacing disturbance, becoming a carbon sink by 20 years for all ecosystems and by 10 years for most. Maximum carbon losses following disturbance (g C m−2y−1) ranged from 1270 in Florida to 200 in boreal ecosystems. Similarly, for forests less than 100 years old, maximum uptake (g C m−2y−1) was 1180 in Florida mangroves and 210 in boreal ecosystems. More temperate forests had intermediate fluxes. Boreal ecosystems were relatively time invariant after 20 years, whereas western ecosystems tended to increase in carbon gain over time. This was driven mostly by gross photosynthetic production (GPP) because total ecosystem respiration (ER) and heterotrophic respiration were relatively invariant with age. GPP/ER was as low as 0.2 immediately following stand-replacing disturbance reaching a constant value of 1.2 after 20 years. NEP following insect defoliations and silvicultural thinning showed lesser changes than stand-replacing events, with decreases in the year of disturbance followed by rapid recovery. NEP decreased in a mangrove ecosystem following Hurricane Wilma because of a decrease in GPP and an increase in ER.

794 citations

Book
01 Jan 1985
TL;DR: Gelfand-Kirillov dimension of algebras Gelfand and Kirillov dimensions of related algesbras Localization Modules Graded and filtered algebraes and modules Almost commutative algebaes Weyl algebras Enveloping algebroes of solvable Lie algebeas Polynomial identitiy algeblas Growth of groups New developments Bibliography Index as discussed by the authors.
Abstract: Introduction Growth of algebras Gelfand-Kirillov dimension of algebras Gelfand-Kirillov dimension of related algebras Localization Modules Graded and filtered algebras and modules Almost commutative algebras Weyl algebras Enveloping algebras of solvable Lie algebras Polynomial identitiy algebras Growth of groups New developments Bibliography Index.

793 citations

Journal ArticleDOI
TL;DR: Regression analyses indicated that greater overall activity level was related to greater happiness, better function, and reduced mortality, and the results suggest that different types of activities may have different benefits.
Abstract: Objectives. Activity has long been thought to be related to successul aging. This study was designed to examine longitudinally the relation between everyday activities and indicators of successful aging, namely well-being, function, and mortality. Methods. The study was based on the Aging in Manitoba Study, with activity being measured in 1990 and function, well-being, and mortality assessed in 1996. Well-being was measured in terms of life satisfaction and happiness; function was defined in terms of a composite measure combining physical and cognitive function. Results. Regression analyses indicated that greater overall activity level was related to greater happiness, better function, and reduced mortality. Different activities were related to different outcome measures; but generally, social and productive activities were positively related to happiness, function, and mortality, whereas more solitary activities (e.g., handwork hobbies) were related only to happiness. Discussion. These findings highlight the importance of activity in successful aging. The results also suggest that different types of activities may have different benefits. Whereas social and productive activities may afford physical benefits, as reflected in better function and greater longevity, more solitary activities, such as reading, may have more psychological benefits by providing a sense of engagement with life.

792 citations

Journal ArticleDOI
TL;DR: The striking synteny of the Chlamydia genomes and prevalence of tandemly duplicated genes are evidence of minimal chromosome rearrangement and foreign gene uptake, presumably owing to the ecological isolation of the obligate intracellular parasites.
Abstract: The genome sequences of Chlamydia trachomatis mouse pneumonitis (MoPn) strain Nigg (1 069 412 nt) and Chlamydia pneumoniae strain AR39 (1 229 853 nt) were determined using a random shotgun strategy. The MoPn genome exhibited a general conservation of gene order and content with the previously sequenced C.trachomatis serovar D. Differences between C.trachomatis strains were focused on an ~50 kb ‘plasticity zone’ near the termination origins. In this region MoPn contained three copies of a novel gene encoding a >3000 amino acid toxin homologous to a predicted toxin from Escherichia coli 0157:H7 but had apparently lost the tryptophan biosyntheis genes found in serovar D in this region. The C.pneumoniae AR39 chromosome was >99.9% identical to the previously sequenced C.pneumoniae CWL029 genome, however, comparative analysis identified an invertible DNA segment upstream of the uridine kinase gene which was in different orientations in the two genomes. AR39 also contained a novel 4524 nt circular single-stranded (ss)DNA bacteriophage, the first time a virus has been reported infecting C.pneumoniae. Although the chlamydial genomes were highly conserved, there were intriguing differences in key nucleotide salvage pathways: C.pneumoniae has a uridine kinase gene for dUTP production, MoPn has a uracil phosphororibosyl transferase, while C.trachomatis serovar D contains neither gene. Chromosomal comparison revealed that there had been multiple large inversion events since the species divergence of C.trachomatis and C.pneumoniae, apparently oriented around the axis of the origin of replication and the termination region. The striking synteny of the Chlamydia genomes and prevalence of tandemly duplicated genes are evidence of minimal chromosome rearrangement and foreign gene uptake, presumably owing to the ecological isolation of the obligate intracellular parasites. In the absence of genetic analysis, comparative genomics will continue to provide insight into the virulence mechanisms of these important human pathogens.

786 citations


Authors

Showing all 32123 results

NameH-indexPapersCitations
George Davey Smith2242540248373
Peer Bork206697245427
David A. Weitz1781038114182
Yang Yang1712644153049
Robert E. W. Hancock15277588481
Peter B. Jones145185794641
Peter Lang140113698592
James J. Gross139529100206
Steven J.M. Jones137594146609
Rajkumar Buyya133106695164
Jeff A. Sloan12965665308
Dafna D. Gladman129103675273
Murray B. Stein12874589513
Robert W. Heath128104973171
Jürgen Rehm1261132116037
Network Information
Related Institutions (5)
University of British Columbia
209.6K papers, 9.2M citations

97% related

University of Toronto
294.9K papers, 13.5M citations

96% related

University of Minnesota
257.9K papers, 11.9M citations

94% related

University of Wisconsin-Madison
237.5K papers, 11.8M citations

92% related

University of Pittsburgh
201K papers, 9.6M citations

92% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202392
2022370
20213,949
20203,547
20193,282
20183,024