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Institution

University of Manitoba

EducationWinnipeg, Manitoba, Canada
About: University of Manitoba is a education organization based out in Winnipeg, Manitoba, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 31888 authors who have published 66592 publications receiving 2095493 citations.


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Journal ArticleDOI
TL;DR: The authors investigated the role of talk and writing on learning science and found that combining talk with writing appears to enhance the retention of science learning over time, and that gender and ability may be important mediating variables that determine the effectiveness of talking and writing for enhancing learning.
Abstract: This study investigated the role of talk and writing on learning science. The purpose was to explore the effect of talk, writing, and talk and writing on the learning and retention of simple and integrated knowledge, and to describe the mechanisms by which talk and writing mediate these processes. Forty-three students were randomly assigned to four groups, all stratified for gender and ability. At intervals during an instructional unit, three treatment groups received problem tasks that involved constructing scientific explanations for real-world applications of ecological concepts. A control group received simpler descriptive tasks based on similar content. Students in the talk-only treatment group (T) discussed the problem tasks in small peer groups. Students in the writing-only treatment group (W) individually wrote responses for each of the tasks, but without first talking to other students. Students in the combined talk and writing treatment group (TW) discussed the problems in groups prior to individually writing their explanations. Dependent variables included simple, integrated, and total knowledge scores based on multiple-choice tests, essay questions, and concept maps obtained at three timepoints during the study: a pretest; an immediate posttest; and a delayed posttest. Records of student talk and writing were also analyzed to describe the mechanisms involved. The findings suggest that talk is important for sharing, clarifying, and distributing knowledge among peers, while asking questions, hypothesizing, explaining, and formulating ideas together are all important mechanisms during peer discussions. Analytical writing is an important tool for transforming rudimentary ideas into knowledge that is more coherent and structured. Furthermore, talk combined with writing appears to enhance the retention of science learning over time. Moreover, gender and ability may be important mediating variables that determine the effectiveness of talk and writing for enhancing learning. © 2000 John Wiley & Sons, Inc. Sci Ed84:566–593, 2000.

416 citations

Journal ArticleDOI
TL;DR: Effects on energy generation clearly play a major role in the activity of eugenol and cinnamaldehyde at bactericidal concentrations, and the possible mechanisms of inhibition of energy generation are inhibition of glucose uptake or utilization of glucose and effects on membrane permeability.
Abstract: The spice oil components eugenol and cinnamaldehyde possess activity against both gram-positive and gram-negative bacteria, but the mechanisms of action remain obscure In broth media at 20°C, 5 mM eugenol or 30 mM cinnamaldehyde was bactericidal (>1-log reduction in the number of CFU per milliliter in 1 h) to Listeria monocytogenes At a concentration of 6 mM eugenol was bactericidal to Lactobacillus sakei, but treatment with 05 M cinnamaldehyde had no significant effect To investigate the role of interference with energy generation in the mechanism of action, the cellular and extracellular ATP levels of cells in HEPES buffer at 20°C were measured Treatment of nonenergized L monocytogenes with 5 mM eugenol, 40 mM cinnamaldehyde, or 10 μM carbonyl cyanide m-chlorophenylhydrazone (CCCP) for 5 min prevented an increase in the cellular ATP concentration upon addition of glucose Treatment of energized L monocytogenes with 40 mM cinnamaldehyde or 10 μM CCCP caused a rapid decline in cellular ATP levels, but 5 mM eugenol had no effect on cellular ATP Treatment of L sakei with 10 mM eugenol prevented ATP generation by nonenergized cells and had no effect on the cellular ATP of energized cells CCCP at a concentration of 100 μM had no significant effect on the cellular ATP of L sakei No significant changes in extracellular ATP were observed Due to their rapidity, effects on energy generation clearly play a major role in the activity of eugenol and cinnamaldehyde at bactericidal concentrations The possible mechanisms of inhibition of energy generation are inhibition of glucose uptake or utilization of glucose and effects on membrane permeability

416 citations

Journal ArticleDOI
TL;DR: In this article, a simple equivalent circuit to represent the thermal heat flow equations for power transformers is presented, which uses a current source analogy to represent heat input due to losses, and a nonlinear resistor analogy to simulate the effect of air or oil cooling convection currents.
Abstract: A simple equivalent circuit to represent the thermal heat flow equations for power transformers is presented. Key features are the use of a current source analogy to represent heat input due to losses, and a nonlinear resistor analogy to represent the effect of air or oil cooling convection currents. The effect was first quantified in 1817. It is shown that the idea of "exponential response" is not the best way to think of the dynamics of the situation. It is also shown that one can consider ambient temperature to be a variable input to the system, and that it is properly represented as an ideal voltage source.

416 citations

Journal ArticleDOI
Sean Walkowiak1, Sean Walkowiak2, Liangliang Gao3, Cécile Monat4, Georg Haberer, Mulualem T. Kassa5, Jemima Brinton6, Ricardo H. Ramirez-Gonzalez6, Markus C. Kolodziej7, Emily Delorean3, Dinushika Thambugala8, Valentyna Klymiuk1, Brook Byrns1, Heidrun Gundlach, Venkat Bandi1, Jorge Nunez Siri1, Kirby T. Nilsen1, Catharine Aquino, Axel Himmelbach4, Dario Copetti9, Dario Copetti7, Tomohiro Ban10, Luca Venturini11, Michael W. Bevan6, Bernardo J. Clavijo6, Dal-Hoe Koo3, Jennifer Ens1, Krystalee Wiebe1, Amidou N’Diaye1, Allen K. Fritz3, Carl Gutwin1, Anne Fiebig4, Christine Fosker6, Bin Xiao Fu2, Gonzalo Garcia Accinelli6, Keith A. Gardner, Nick Fradgley, Juan J. Gutierrez-Gonzalez12, Gwyneth Halstead-Nussloch7, Masaomi Hatakeyama7, Chu Shin Koh1, Jasline Deek13, Alejandro C. Costamagna14, Pierre R. Fobert5, Darren Heavens6, Hiroyuki Kanamori, Kanako Kawaura10, Fuminori Kobayashi, Ksenia V. Krasileva6, Tony Kuo15, Tony Kuo16, Neil McKenzie6, Kazuki Murata17, Yusuke Nabeka17, Timothy Paape7, Sudharsan Padmarasu4, Lawrence Percival-Alwyn, Sateesh Kagale5, Uwe Scholz4, Jun Sese16, Philomin Juliana18, Ravi P. Singh18, Rie Shimizu-Inatsugi7, David Swarbreck6, James Cockram, Hikmet Budak, Toshiaki Tameshige10, Tsuyoshi Tanaka, Hiroyuki Tsuji10, Jonathan M. Wright6, Jianzhong Wu, Burkhard Steuernagel6, Ian Small19, Sylvie Cloutier8, Gabriel Keeble-Gagnère, Gary J. Muehlbauer12, Josquin Tibbets, Shuhei Nasuda17, Joanna Melonek19, Pierre Hucl1, Andrew G. Sharpe1, Matthew D. Clark11, Erik Legg20, Arvind K. Bharti20, Peter Langridge21, Anthony Hall6, Cristobal Uauy6, Martin Mascher4, Simon G. Krattinger7, Simon G. Krattinger22, Hirokazu Handa23, Kentaro Shimizu7, Kentaro Shimizu10, Assaf Distelfeld24, Kenneth J. Chalmers21, Beat Keller7, Klaus F. X. Mayer25, Jesse Poland3, Nils Stein4, Nils Stein26, Curt A. McCartney8, Manuel Spannagl, Thomas Wicker7, Curtis J. Pozniak1 
25 Nov 2020-Nature
TL;DR: Comparative analysis of multiple genome assemblies from wheat reveals extensive diversity that results from the complex breeding history of wheat and provides a basis for further potential improvements to this important food crop.
Abstract: Advances in genomics have expedited the improvement of several agriculturally important crops but similar efforts in wheat (Triticum spp.) have been more challenging. This is largely owing to the size and complexity of the wheat genome1, and the lack of genome-assembly data for multiple wheat lines2,3. Here we generated ten chromosome pseudomolecule and five scaffold assemblies of hexaploid wheat to explore the genomic diversity among wheat lines from global breeding programs. Comparative analysis revealed extensive structural rearrangements, introgressions from wild relatives and differences in gene content resulting from complex breeding histories aimed at improving adaptation to diverse environments, grain yield and quality, and resistance to stresses4,5. We provide examples outlining the utility of these genomes, including a detailed multi-genome-derived nucleotide-binding leucine-rich repeat protein repertoire involved in disease resistance and the characterization of Sm16, a gene associated with insect resistance. These genome assemblies will provide a basis for functional gene discovery and breeding to deliver the next generation of modern wheat cultivars.

416 citations

Journal ArticleDOI
TL;DR: The current guideline updates the recommendations of the 2005 guideline, includes new recommendations for populations not previously addressed, and, where relevant, addresses the interpretation of nonlocalizing clinical symptoms in populations with a high prevalence of ASB.
Abstract: Asymptomatic bacteriuria (ASB) is a common finding in many populations, including healthy women and persons with underlying urologic abnormalities. The 2005 guideline from the Infectious Diseases Society of America recommended that ASB should be screened for and treated only in pregnant women or in an individual prior to undergoing invasive urologic procedures. Treatment was not recommended for healthy women; older women or men; or persons with diabetes, indwelling catheters, or spinal cord injury. The guideline did not address children and some adult populations, including patients with neutropenia, solid organ transplants, and nonurologic surgery. In the years since the publication of the guideline, further information relevant to ASB has become available. In addition, antimicrobial treatment of ASB has been recognized as an important contributor to inappropriate antimicrobial use, which promotes emergence of antimicrobial resistance. The current guideline updates the recommendations of the 2005 guideline, includes new recommendations for populations not previously addressed, and, where relevant, addresses the interpretation of nonlocalizing clinical symptoms in populations with a high prevalence of ASB.

416 citations


Authors

Showing all 32123 results

NameH-indexPapersCitations
George Davey Smith2242540248373
Peer Bork206697245427
David A. Weitz1781038114182
Yang Yang1712644153049
Robert E. W. Hancock15277588481
Peter B. Jones145185794641
Peter Lang140113698592
James J. Gross139529100206
Steven J.M. Jones137594146609
Rajkumar Buyya133106695164
Jeff A. Sloan12965665308
Dafna D. Gladman129103675273
Murray B. Stein12874589513
Robert W. Heath128104973171
Jürgen Rehm1261132116037
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202392
2022370
20213,949
20203,547
20193,282
20183,024