University of Perugia

About: University of Perugia is a education organization based out in Perugia, Umbria, Italy. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 13365 authors who have published 39516 publications receiving 1265601 citations. The organization is also known as: Universitá degli Studi di Perugia & Universita degli Studi di Perugia.

Cell encapsulation: promise and progress.

Abstract: 1proposed the idea of using ultrathin polymer membrane microcapsules for the immunoprotection of transplanted cells and introduced the term ‘artificial cells’ to define the concept of bioencapsulation, which was successfully implemented 20 years later to immobilize xenograft islet cells. When implanted into rats, the microencapsulated islets corrected the diabetic state for several weeks 2 . Since then, there has been considerable progress toward understanding the biological and technological requirements for successful transplantation of encapsulated cells in experimental animal models, including rodents and non-human primates. Bioencapsulation has provided a range of promising therapeutic treatments for diabetes 3 , hemophilia 4 , cancer 5 and renal failure 6 . Additionally, the functional applicability of cell encapsulation in humans has also been reported in several clinical trials 7,8

Giant Intermolecular Decay and Fragmentation of Clusters

Abstract: In sharp contrast to molecules, electronic states of clusters with an excited intermediate-shell electron can efficiently decay via an intermolecular Coulombic mechanism. Explicit examples are presented using large scale {ital ab initio} propagator calculations. The mechanism is illustrated and its generality is stressed. {copyright} {ital 1997} {ital The American Physical Society}