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Showing papers in "Clinical Neurophysiology in 2021"


Journal ArticleDOI
TL;DR: New operational guidelines are provided for safety in planning future trials based on traditional and patterned TMS protocols, as well as a summary of the minimal training requirements for operators, and a note on ethics of neuroenhancement.

387 citations


Journal ArticleDOI
TL;DR: In this paper, the electrophysiological features and plasma biomarkers of critical illness polyneuropathy (CIN) and myopathy (CIM) in COVID-19 patients with intensive care unit acquired weakness (ICUAW).

73 citations




Journal ArticleDOI
TL;DR: Myopathy may be an important cause of physical fatigue in long-term COVID-19 even in non-hospitalized patients, and changes in one or more muscles in 11 patients showed myopathic changes.

52 citations


Journal ArticleDOI
TL;DR: In this paper, the authors applied transcranial magnetic stimulation (TMS) to explore the activity of the main inhibitory intracortical circuits within the primary motor cortex (M1) in a sample of patients complaining of fatigue and presenting executive dysfunction after resolution of COVID-19 with neurological manifestations.

41 citations


Journal ArticleDOI
TL;DR: Recommendations on the structure and content of NIBS training are provided, basic or core competencies and more advanced knowledge and skills are discussed, and recommendations offered regarding didactic and practical curricular components.

36 citations


Journal ArticleDOI
TL;DR: A review of different approaches to IED detection can be found in this article, where the authors discuss their performance and limitations, as well as the standardization of datasets and outcome measures.

35 citations


Journal ArticleDOI
TL;DR: The clinical practice guideline (CPG) as discussed by the authors provides recommendations for healthcare personnel working with patients with epilepsy, on the use of wearable devices for automated seizure detection in patients in outpatient, ambulatory settings.

33 citations


Journal ArticleDOI
TL;DR: In this article, the prevalence of subclinical epileptiform activity (SEA) in Alzheimer's patients compared to healthy elderly controls was determined, with the hypothesis that SEA is more frequent in Alzheimer patients than in cognitively normal individuals.

32 citations


Journal ArticleDOI
TL;DR: AED therapy induces EEG modifications in TLE patients, and such modifications are predictive of clinical outcome, and Quantitative EEG may help understanding the effect of AEDs in the central nervous system and offer new prognostic biomarkers for patients with epilepsy.


Journal ArticleDOI
TL;DR: The two architectures of ANNs using stacked (autoencoding) hidden layers consistently reached moderate to high accuracy in the discrimination between ADD and healthy control participants as a function of the rsEEG and sMRI features employed.

Journal ArticleDOI
TL;DR: The background of EIM is presented, including the relation between EIM, volume conduction properties, tissue structure, electrode configuration and conductor volume, and its limitations and strengths.

Journal ArticleDOI
TL;DR: In this paper, a large-scale analysis has identified a number of factors influencing participants' responses to single and paired-pulse TMS, including target muscle, pulse waveform, neuronavigation use, and TMS machine.

Journal ArticleDOI
TL;DR: In this paper, the effects of repetitive transcranial magnetic stimulation (rTMS) on TMS-EEG measures in TRD were investigated using a double blind 2:1 randomized active and sham rTMS TRD trial.

Journal ArticleDOI
TL;DR: In this article, a machine learning-based approach was applied to diagnose Parkinson's disease (PD) using EEG time-series as input and predicted class-labels as output, i.e. best vs. worst cognitive performance.

Journal ArticleDOI
TL;DR: TDCS showed adjuvant effects to detoxification in the management of patients with CM and MOH and showed a significant potentiation of alpha rhythm, which may represent a correlate of the underlying changes in cortico-thalamic connections.

Journal ArticleDOI
TL;DR: Empirical support is provided for the theory that delirium is a disorder of reduced functional brain integration, and EEG appears to have utility in differentiating those with and withoutDelirium vulnerability and the long-term effects on brain function require further investigation.

Journal ArticleDOI
TL;DR: In this paper, a multi-layer neural network was applied, combining with a three-layer convolutional neural network, a layer of long and short-term memory network (LSTM), and a layer with LSTM with Attention mechanism.

Journal ArticleDOI
TL;DR: In this article, a meta-analysis and nine subgroup-analyses were performed to identify which tDCS parameters yielded the greatest impact on upper limb function recovery in stroke patients.

Journal ArticleDOI
TL;DR: Systematic early EEG detection of encephalopathy related to severe COVID-19 is important for the acute care and the management of long-term neurological and cognitive sequelae, and may help the better understanding of its pathophysiology.


Journal ArticleDOI
TL;DR: In this article, the authors used a randomized double-blind active-controlled crossover study of 19 unmedicated children with ADHD, who received either anodal transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (dlPFC) or random noise stimulation over the bilateral dlPFC, while completing executive functions training.

Journal ArticleDOI
TL;DR: In this paper, the authors used histopathology and neurophysiology signals to leverage current and novel biomarkers for the localization of epileptic activity in the human brain, including seizure onset, spikes, and oscillatory activity in delta, theta, gamma and ripple frequency bands.

Journal ArticleDOI
TL;DR: The proposed algorithm achieved a significantly higher specificity than state-of-the-art algorithm, with only minor decrease in sensitivity for patients with sleep disorders.

Journal ArticleDOI
TL;DR: In this article, the authors used high-density EEG (HD-EEG) recordings of focal drug-resistant epilepsy patients with seizure-free postsurgical outcome to detect and localize the epileptogenic zone (EZ).

Journal ArticleDOI
TL;DR: In this paper, the brain changes after spaceflight and simulated spaceflight involve several mechanisms. But only a few studies have investigated in detail the complexity of neurophysiological systems and their integration to maintain homeostasis.

Journal ArticleDOI
TL;DR: In this paper, the authors describe and evaluate the concepts of near fiber electromyography (NFEMG), the features used, including near fiber motor unit potential (NFMUP) duration and dispersion, which relate to motor unit distal axonal branch and muscle fiber conduction time dispersion.

Journal ArticleDOI
TL;DR: In this paper, the authors evaluated diagnostic accuracy of the proposed 'Gold Coast' (GC) diagnostic criteria for amyotrophic lateral sclerosis (ALS) in five European centres retrospectively sampled consecutive patients referred for electromyography on suspicion of ALS.