Journal ArticleDOI
Attenuation of Oxidative Stress After Varicocelectomy in Subfertile Patients With Varicocele
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TLDR
Subfertile patients with varicocele had a significant decrease in oxidative damage in sperm DNA and an increase in antioxidant capacity in seminal plasma after varicocelectomy, indicating that surgery is effective treatment in such patients.About:
This article is published in The Journal of Urology.The article was published on 2008-02-01. It has received 111 citations till now. The article focuses on the topics: Varicocele & Semen analysis.read more
Citations
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Journal ArticleDOI
Oxidative stress and male infertility—a clinical perspective
TL;DR: This review will provide an overview of oxidative biochemistry related to sperm health and identify which men are most at risk of oxidative infertility, and outline methods available for diagnosing oxidative stress and the various treatments available.
Journal ArticleDOI
Varicocele and male factor infertility treatment: a new meta-analysis and review of the role of varicocele repair.
Abdulaziz Baazeem,Eric Belzile,Antonio Ciampi,Gert R. Dohle,Keith Jarvi,Andrea Salonia,Wolfgang Weidner,Armand Zini +7 more
TL;DR: Although there is no conclusive evidence that a varicocele repair improves spontaneous pregnancy rates, varicocelectomy improves sperm parameters (count and total and progressive motility), reduces sperm DNA damage and seminal oxidative stress, and improves sperm ultramorphology.
Journal ArticleDOI
Sperm DNA damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility.
TL;DR: DNA fragmentation is an important factor in the aetiology of male infertility, however it is still underevaluated and its inclusion in routine semen analysis is debated, and sources of oxidative stress should be thoroughly examined in men with high levels of DNA fragmentation and modified where possible.
Journal ArticleDOI
Oxidative stress and sperm function: A systematic review on evaluation and management
TL;DR: OS is an important cause of male factor infertility and its assessment provides essential information that can guide treatment strategies aimed at improving the male’s reproductive potential.
Journal ArticleDOI
Male Oxidative Stress Infertility (MOSI): Proposed Terminology and Clinical Practice Guidelines for Management of Idiopathic Male Infertility
Ashok Agarwal,Neel Parekh,Manesh Kumar Panner Selvam,Ralf Henkel,Ralf Henkel,Rupin Shah,Sheryl T. Homa,Ranjith Ramasamy,Edmund Y. Ko,Kelton Tremellen,Sandro C. Esteves,Sandro C. Esteves,Ahmad Majzoub,Ahmad Majzoub,Juan G. Alvarez,David K. Gardner,Channa N. Jayasena,Channa N. Jayasena,Jonathan Ramsay,Chak-Lam Cho,Ramadan A Saleh,Denny Sakkas,James M. Hotaling,Scott Lundy,Sarah C. Vij,Joel L. Marmar,Jaime Gosálvez,Edmund Sabanegh,Hyun Jun Park,Armand Zini,Parviz Kavoussi,Sava Micic,Ryan P. Smith,Gian Maria Busetto,Mustafa Emre Bakircioglu,Gerhard Haidl,Giancarlo Balercia,Nicolás Garrido Puchalt,Moncef Ben-Khalifa,Nicholas N. Tadros,Jackson Kirkman-Browne,Sergey I. Moskovtsev,Xuefeng Huang,Edson Borges,Daniel R. Franken,Natan Bar-Chama,Yoshiharu Morimoto,Kazuhisa Tomita,Vasan Satya Srini,Willem Ombelet,Elisabetta Baldi,Monica Muratori,Yasushi Yumura,Sandro La Vignera,Raghavender Kosgi,Marlon Martinez,Donald P. Evenson,Daniel Suslik Zylbersztejn,Matheus Roque,Marcello Cocuzza,Marcelo Vieira,Assaf Ben-Meir,Raoul Orvieto,Raoul Orvieto,Eliahu Levitas,Amir Wiser,Amir Wiser,Mohamed Arafa,Vineet Malhotra,Sijo Parekattil,Haitham Elbardisi,Luiz Carvalho,Rima Dada,Christophe Sifer,Pankaj Talwar,Ahmet Gudeloglu,Ahmed M A Mahmoud,Khaled Terras,Chadi Yazbeck,Bojanic Nebojsa,Damayanthi Durairajanayagam,Ajina Mounir,Linda G. Kahn,Saradha Baskaran,Rishma Pai,Donatella Paoli,Kristian Leisegang,Mohamed Reza Moein,Sonia Malik,Önder Yaman,Luna Samanta,Fouad Bayane,Sunil Jindal,Muammer Kendirci,Barış Altay,Dragoljub Perovic,Avi Harlev +96 more
TL;DR: Oxidation-reduction potential (ORP) can be a useful clinical biomarker for the classification of MOSI, as it takes into account the levels of both oxidants and reductants (antioxidants) and may provide a more targeted, reliable approach for administering antioxidant therapy while minimizing the risk of antioxidant overdose.
References
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Laboratory manual for the examination of human semen and semen-cervical mucus interaction.
TL;DR: This laboratory manual consists of 2 sections which describe methods of examination of human semen and semen-cervical mucus interaction in order to standardize procedures and facilitate evaluation and comparison of research reports.
Journal ArticleDOI
A methodology for analysis of tissue sulfhydryl components.
Alan F. Boyne,George L. Ellman +1 more
TL;DR: A methodology is described for the analysis of tissue SH components of a single tissue sample in terms of soluble and insoluble, reactive and unreactive, SH, using the SH reagent DTNB.
Journal ArticleDOI
Relationship between oxidative stress, semen characteristics, and clinical diagnosis in men undergoing infertility investigation
TL;DR: Irrespective of the clinical diagnosis and semen characteristics, the presence of seminal oxidative stress in infertile men suggests its role in the pathophysiology of infertility.
Book ChapterDOI
Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection.
TL;DR: The quantitative approach may allow one to estimate oxidative DNA damage in an animal or individual exposed to prooxidant conditions associated with lifestyle, genetic predisposition, degenerative diseases, or environmental toxins by estimating the rate of oxidative DNA damaged within the body or in a population of cells.
Journal ArticleDOI
Assessment of efficacy of varicocele repair for male subfertility: a systematic review
TL;DR: Varicocele repair does not seem to be an effective treatment for male or unexplained subfertility and may have had insufficient power to detect small effects because of the small number of patients in some subgroups.