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Biopolymer-based functional composites for medical applications

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TLDR
This article provides comprehensive knowledge and highlights recent research on functional biopolymer composites used in various medical applications, such as tissue engineering comprising skin, bone, cartilage, vascular graft, and other organs, implantable medical devices including stent and barrier membrane, and some delivery systems of bioactive agents.
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This article is published in Progress in Polymer Science.The article was published on 2017-05-01. It has received 247 citations till now.

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Nanowired three-dimensional cardiac patches

TL;DR: Incorporating gold nanowires into scaffolds used to create heart patches can improve electrical communication between cells and enhance the growth of tissues as discussed by the authors, which can improve the electrical communication among cells.
Journal ArticleDOI

Advanced Materials by Atom Transfer Radical Polymerization

TL;DR: Atom transfer radical polymerization (ATRP) has been successfully employed for the preparation of various advanced materials with controlled architecture as discussed by the authors, such as thermoplastic elastomers, nanostructured carbons, surfactants, dispersants, functionalized surfaces, and biorelated materials.
Journal ArticleDOI

A comprehensive review on chemical properties and applications of biopolymers and their composites.

TL;DR: The motive of this paper is to shimmer light on some aspects of biopolymers that include its classes, properties, composites and applications.
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Current advances and future perspectives of 3D printing natural-derived biopolymers.

TL;DR: This paper reviews the state-of-the-art in terms of 3D printing technology using natural-derived feedstocks, including lignocellulose, starch, algae, and chitosan-based biopolymers, and proposes a strategical development roadmap with identified material property requirements, key challenges, as well as possible solutions.
Journal ArticleDOI

Bacterial cellulose-based scaffold materials for bone tissue engineering

TL;DR: Detailed requirements of scaffold materials for bone tissue engineering are reviewed, and comprehensive knowledge and highlights of current research on bacterial cellulose composites used for tissue engineering and the potentials ofacterial cellulose for bone regeneration including other nanoparticles incorporated are provided.
References
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Journal ArticleDOI

Nanotopography Promotes Pancreatic Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells

TL;DR: It is reported that polystyrene nanopore-patterned surfaces significantly promote the pancreatic differentiation of human embryonic and induced pluripotent stem cells and that appropriate cytokine treatments combined with nanotopographical stimulation could be a powerful tool for deriving a high purity of desired cells from human pluripoline stem cells.
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Enzymatic breakdown of poly-gamma-D-glutamic acid in Bacillus licheniformis: identification of a polyglutamyl gamma-hydrolase enzyme.

TL;DR: Examination of 14C-labeled reaction products indicated that the enzyme is an endo-type hydrolase, which catalyses the hydrolytic breakdown of poly-gamma-D-glutamic acid from Bacillus licheniformis 9945a.
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Biodegradable Nanotopography Combined with Neurotrophic Signals Enhances Contact Guidance and Neuronal Differentiation of Human Neural Stem Cells

TL;DR: Biodegradable polymer substrates with nanoscale topography for enhancing human NSC (hNSC) differentiation and guided neurite outgrowth and the addition of nerve growth factor enhanced neuronal differentiation of hNSCs, indicating a synergistic effect of biophysical and biochemical cues on NSC differentiation.
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Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing

TL;DR: A microphysiological three-dimensional engineered human skeletal muscle system connected to a circulatory system that consists of a tissue-engineered blood vessel as part of a high-pressure arterial system that reproduces key mechanical behaviors of skeletal muscle in vivo is developed.
Journal ArticleDOI

Biodegradable poly(l-lactide) composites by oligolactide-grafted magnesium hydroxide for mechanical reinforcement and reduced inflammation

TL;DR: A novel composite system composed of PLLA and oligolactide-grafted magnesium hydroxide (Mg-OLA) that can overcome drawbacks caused by poor mechanical properties and inflammatory response of PllA for biomedical applications is suggested.
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