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Open AccessJournal ArticleDOI

BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting.

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TLDR
This study in a nationwide mass vaccination setting suggests that the BNT162b2 mRNA vaccine is effective for a wide range of Covid-19–related outcomes, a finding consistent with that of the randomized trial.
Abstract
Background As mass vaccination campaigns against coronavirus disease 2019 (Covid-19) commence worldwide, vaccine effectiveness needs to be assessed for a range of outcomes across diverse p...

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Eight Good Reasons for Careful Monitoring and Evaluation of the Vaccine Campaign against COVID-19: Lessons Learned through the Lombardy Experience for Dealing with Next Challenges

TL;DR: The reduced effectiveness of the vaccine over time was studied and identified risk factors of post-vaccine infection and severe illness and the correct use of rapidly available observational data of good quality and completeness generates reliable evidence to inform patients and policymakers.
Journal ArticleDOI

IgG anti-spike antibody levels in healthcare workers with and without prior COVID-19 up to 3 months after BNT162b2 vaccination

TL;DR: In this article , the authors report that the antibody response was significantly stronger in previously infected vaccinated HCW compared to uninfected HCW, and stronger after vaccination compared to mild natural infection.
Journal ArticleDOI

Efficacy of COVID-19 vaccines

TL;DR: In this paper , the relative effectiveness of three approved vaccines against COVID-19 in a sample of the Jordanian population was evaluated in an observational study conducted between July 2021 and 2022.
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Is COVID vaccine effective in patients with myeloid malignancy?

TL;DR: In this paper , the authors present a list of immune neoplasms of COVID patients, which includes the following neoplasm types: (1) Crohn's disease.
References
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Book ChapterDOI

Nonparametric Estimation from Incomplete Observations

TL;DR: In this article, the product-limit (PL) estimator was proposed to estimate the proportion of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t).
Journal ArticleDOI

Validation of a combined comorbidity index.

TL;DR: The estimated relative risk of death from an increase of one in the comorbidity score proved approximately equal to that from an additional decade of age.
Journal ArticleDOI

Using Big Data to Emulate a Target Trial When a Randomized Trial Is Not Available

TL;DR: This work outlines a framework for comparative effectiveness research using big data that makes the target trial explicit and channels counterfactual theory for comparing the effects of sustained treatment strategies, organizes analytic approaches, provides a structured process for the criticism of observational studies, and helps avoid common methodologic pitfalls.
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Trending Questions (1)
How much RNA is in Covid vaccine?

This study in a nationwide mass vaccination setting suggests that the BNT162b2 mRNA vaccine is effective for a wide range of Covid-19–related outcomes, a finding consistent with that of the randomized trial.