BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting.
Noa Dagan,Noam Barda,Noam Barda,Noam Barda,Eldad Kepten,Oren Miron,Oren Miron,Shay Perchik,Mark A. Katz,Mark A. Katz,Mark A. Katz,Miguel A. Hernán,Marc Lipsitch,Ben Y. Reis,Ran D. Balicer,Ran D. Balicer +15 more
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TLDR
This study in a nationwide mass vaccination setting suggests that the BNT162b2 mRNA vaccine is effective for a wide range of Covid-19–related outcomes, a finding consistent with that of the randomized trial.Abstract:
Background As mass vaccination campaigns against coronavirus disease 2019 (Covid-19) commence worldwide, vaccine effectiveness needs to be assessed for a range of outcomes across diverse p...read more
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Neutralizing Activity and SARS-CoV-2 Vaccine mRNA Persistence in Serum and Breastmilk After BNT162b2 Vaccination in Lactating Women
Kee Thai Yeo,Wan Ni Chia,Chee Wah Tan,Chengsi Ong,Joo Guan Yeo,Jinyan Zhang,Su Li Poh,Amanda Lim,Kirsten Hui Zhi Sim,N. Sutamam,Camillus Chua,Salvatore Albani,Lin-Fa Wang,Mei Chien Chua +13 more
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COVID-19 vaccinations are associated with reduced fatality rates: Evidence from cross-county quasi-experiments.
TL;DR: In this article, the authors evaluated the association of COVID-19 vaccine coverage with case fatality ratio (CFR) on a global scale and found that a 10% increase in vaccine coverage was associated with a 7.6% reduction in the CFR (95% confidence interval (CI = -12.6 to -2.7%, P = 0.002).
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BNT162b2 Messenger RNA COVID-19 Vaccine Effectiveness in Patients With Inflammatory Bowel Disease: Preliminary Real-World Data During Mass Vaccination Campaign.
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Reactogenicity of homologous and heterologous prime-boost immunization with BNT162b2 and ChAdOx1-nCoV19: a prospective cohort study
David Hillus,Tatjana Schwarz,Pinkus Tober-Lau,Hana Hastor,Charlotte Thibeault,Stefanie Kasper,Elisa T Helbig,Lena J Lippert,Patricia Tscheak,Marie Luisa Schmidt,Johanna Riege,Andr Solarek,Christof von Kalle,Chantip Dang-Heine,Piotr Kopankiewicz,Norbert Suttorp,Christian Drosten,Harald Bias,Joachim Seybold,Covim,Florian Kurth,Florian Kurth,Victor M. Corman,Leif E. Sander +23 more
TL;DR: In this paper, a prospective observational cohort study was conducted to assess reactogenicity and immunogenicity of heterologous prime-boost immunisations of ChAdox1-nCoV19 (Vaxzevria, ChAdOx) followed by BNT162b2 (Comirnaty, BNT) compared to homologous BNT/BNT immunisation.
Journal ArticleDOI
The way of SARS-CoV-2 vaccine development: success and challenges.
Yetian Dong,Yetian Dong,Yetian Dong,Tong Dai,Bin Wang,Lei Zhang,Linghui Zeng,Jun Huang,Haiyan Yan,Long Zhang,Fangfang Zhou +10 more
TL;DR: In this paper, the influence of mutational hotspots on the vaccine efficacy and characteristics of variants of interest and concern was discussed. And the authors provided an overview of the duration of immune responses after natural infection or vaccination and shed light on the factors that may affect the immunity induced by the vaccines, such as special disease conditions, sex, and pre-existing immunity, with the aim of aiding in combating COVID-19 and distributing SARS-CoV-2 vaccines under the prevalence of diverse SARS CoV2 variants.
References
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Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine.
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