Journal ArticleDOI
Chronic toxicity of diethyl phthalate in male Wistar rats--a dose-response study.
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It is evident from this study that treatment with higher concentrations of DEP results in mitochondrial proliferation as well as accumulation of glycogen, cholesterol and triglycerides within the liver, but exposure to lower concentrations for longer periods results in increase in peroxisome numbers leading to severe hepatocellular changes.About:
This article is published in Regulatory Toxicology and Pharmacology.The article was published on 2006-07-01. It has received 56 citations till now. The article focuses on the topics: Normal diet & Toxicity.read more
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Correlation of phthalate exposures with semen quality
N. Pant,Manju Shukla,Devendra Kumar Patel,Y. R. Shukla,Neeraj Mathur,Yogendra Kumar Gupta,Daya K. Saxena +6 more
TL;DR: It is suggestive that phthalates might be one among the contributing factors associated with the deterioration in semen quality and these adverse effects might be ROS, LPO and mitochondrial dysfunction mediated.
Journal ArticleDOI
Plasticizer endocrine disruption: Highlighting developmental and reproductive effects in mammals and non-mammalian aquatic species
TL;DR: The aim of this review is to compare the effects of plasticizers in animals, with a focus on aquatic species, and identified three main chains of events that occur in animals exposed to BPA and phthalates.
Journal ArticleDOI
Concentrations of phthalate metabolites in milk, urine, saliva, and Serum of lactating North Carolina women.
TL;DR: The data suggest that phthalate metabolites are most frequently detected in urine of lactating women and are less often detected in serum, milk, or saliva.
Journal ArticleDOI
Oxidative stress and male infertility: current knowledge of pathophysiology and role of antioxidant therapy in disease management
TL;DR: Physiological ROS production, roles of genetic and epigenetic factors on the OS and male infertility with various mechanisms such as lipid peroxidation, DNA damage, and disorder of male hormone profile, inflammation, and varicocele are described.
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Diethylhexyl Phthalates Is Associated with Insulin Resistance via Oxidative Stress in the Elderly: A Panel Study
TL;DR: The study results suggest that exposure to DEHP in the elderly population increases IR, which is related with oxidative stress, and that participants with a history of DM and females are more susceptible toDEHP exposure.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Book
Methods of Enzymatic Analysis
TL;DR: Methods of enzymatic analysis, Methods of enzymes analysis, the authors, Methods of enzyme analysis, enzymatics, methods of enzymes, and methods of analysis, method of enzymes.
Journal ArticleDOI
A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.
Stanley Reitman,Sam Frankel +1 more
Journal ArticleDOI
A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic.
TL;DR: The current finding that some phthalate compounds and some food additives are weakly estrogenic in vitro, needs to be supported by further studies on their effects in vivo before any conclusions can be made regarding their possible role in the development of these conditions.