Journal ArticleDOI
Coronaviruses, a new group of animal RNA viruses.
TLDR
The adequate serological studies can disclose how closely related the viruses are and whether there is a speculative possibility that the IBV strains which are ubiquitous in almost all poultry populations can serve as reservoirs for human common cold infections, e.g. through mutation of IBV or hybridization of animal and human coronaviruses.Citations
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Journal ArticleDOI
Coronavirus RNA Proofreading: Molecular Basis and Therapeutic Targeting.
Fran Robson,Khadija Shahed Khan,Thi Khanh Le,Clément Paris,Sinem Demirbag,Peter Barfuss,Palma Rocchi,Wai-Lung Ng +7 more
TL;DR: The molecular basis of the CoV proofreading complex is reviewed and its potential as a drug target is evaluated and existing nucleoside analogues and novel genomic techniques are considered as potential anti-CoV therapeutics that could be used individually or in combination to target the proofreading mechanism.
Journal ArticleDOI
Clinical Manifestation and Disease Progression in COVID-19 Infection.
Ping Hsing Tsai,Wei Yi Lai,Yi Ying Lin,Yung Hung Luo,Yi Tsung Lin,Hsiao Kang Chen,Yuh Min Chen,Yi Chun Lai,Li Chiao Kuo,Shew Dan Chen,Kao Jung Chang,Cheng Hsuan Liu,Shih-Chieh Chang,Fu Der Wang,Yi Ping Yang +14 more
TL;DR: This review article summarized the general clinical signs and symptoms, radiologic features, and disease manifestation with progression in patients with COVID-19.
Journal ArticleDOI
CRISPR Systems for COVID-19 Diagnosis.
Hossein Rahimi,Marziyeh Salehiabar,Murat Barsbay,Mohammadreza Ghaffarlou,Taras Kavetskyy,Taras Kavetskyy,Ali Sharafi,Soodabeh Davaran,Subhash C. Chauhan,Hossein Danafar,Saeed Kaboli,Hamed Nosrati,Murali M. Yallapu,João Conde +13 more
TL;DR: In this paper, the authors reviewed contemporary studies on the detection of COVID-19 based on the clustered regularly interspaced short palindromic repeats (CRISPR)-based diagnostic system.
Journal ArticleDOI
Protein composition of coronavirus OC 43
TL;DR: A human coronavirus, strain OC 43, was propagated in suckling mouse brain and purified 5000-fold with, a 90% yield, and the association of a host cell antigen with the virion was confirmed by standard HI and CF tests.
Journal ArticleDOI
Antiviral and Immunomodulatory Effects of Phytochemicals from Honey against COVID-19: Potential Mechanisms of Action and Future Directions.
Mohammad A. I. Al-Hatamleh,Ma'mon M. Hatmal,Kamran Sattar,Suhana Ahmad,Mohd Zulkifli Mustafa,Marcelo De Carvalho Bittencourt,Rohimah Mohamud +6 more
TL;DR: Evidence for its role as a potentially effective natural product against COVID-19 is reviewed, exclusively summarizing all bioactive compounds in honey with their probable mechanisms of action as antiviral agents, specifically against SARS-CoV-2.
References
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Journal ArticleDOI
A New Virus Isolated from the Human Respiratory Tract.
Dorothy Hamre,John J. Procknow +1 more
TL;DR: A new ether sensitive RNA virus was isolated during surveillance of URI among medical students in the winter of 1962 and is antigenically unrelated to all known human myxoviruses.
Journal ArticleDOI
Cultivation of a novel type of common-cold virus in organ cultures.
D. A. J. Tyrrell,M. L. Bynoe +1 more
TL;DR: In the past four years efforts have been made to discover something of the nature of such viruses and to devise methods of cultivating them in the laboratory and some success has been achieved and is reported in this paper.
Journal ArticleDOI
Recovery in tracheal organ cultures of novel viruses from patients with respiratory disease.
TL;DR: A sharp decrease in the rate of virus isolation during the winter of 1965-66 was noted, similar to that reported by others, and the recovery and properties of these 6 viruses form the basis of this report.
Journal ArticleDOI
A murine virus (JHM) causing disseminated encephalomyelitis with extensive destruction of myelin.
TL;DR: A description has been given of the pathologic changes produced experimentally in animals by the inoculation of a virus material obtained from a mouse with spontaneous encephalomyelitis, which includes the widespread destruction of myelin.
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